A method for determining a next hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) dosage for a first patient using a patient HIF-PHI model is provided. The method includes obtaining population patient data indicating HIF-PHI dosages and hemoglobin measurements for the patients. Then, virtual patient avatars are generated based on the population patient data. Each of the virtual patient avatars indicates a set of personalized model parameters for a HIF-PHI model. A plurality of HIF-PHI models are determined for the virtual patient avatars. Using the HIF-PHI models, one or more HIF-PHI treatment schemes for administering the HIF-PHI dosages is determined. Subsequently, the HIF-PHI treatment schemes along with a hematocrit and/or hemoglobin concentration for a patient are used to determine a next HIF-PHI dosage for the patient, and the next HIF-PHI dosage is administered for the patient.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
2.
SYSTEM AND METHOD FOR ATTAINING DESIRED OXYGEN DOSING BASED ON ERYTHROPOIESIS MODELING
A computing system for determining a systematic training strategy for the user is provided. The computing system includes a user device that uses one or more sensors to obtain partial pressure of oxygen (PO2) levels of a user over a period of time. The user device provides previous PO2 levels to a personalized erythropoiesis model generation computing platform. The computing platform obtains individualized user data for the user indicating or more previous hematocrit and/or hemoglobin measurements for the user. The computing platform determines an individualized erythropoiesis model for the user based on the one or more previous hematocrit and/or hemoglobin measurements and the previous PO2 information, and employs the individualized erythropoiesis model to determine predicted hematocrit and/or hemoglobin measurements. The computing platform performs one or more actions based on the one or more predicted hematocrit and/or hemoglobin measurements.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
3.
REMOTE MONITORING AND CONTROL OF TREATMENT PARAMETERS ON A MEDICAL DEVICE
A method comprising: establishing a wireless connection between a first medical device and a second medical device, comprising: receiving, by the first medical device, via a short-range wireless technology protocol, connection information related to the second medical device; and establishing, by the first medical device, a wireless connection with the second medical device based on the connection information.
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
4.
SYSTEMS AND METHODS FOR IDENTIFYING DEPRESSION IN A DIALYSIS PATIENT
Detailed herein are systems, methods, and devices configured for detecting symptoms of depression in a home dialysis patient. These systems, methods, and device may be embodied in a home dialysis system. The home dialysis system may be configured to carry out a home dialysis treatment on a patient. During the home dialysis treatment, the home dialysis system may be configured to detect one or more symptoms of depression and to generate a medical alert based on the detected one or more symptoms.
G16H 20/70 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
The present teachings include techniques for securing a connection to a dialyzer or the like—e.g., securing the junction between a dialyzer port and a connector (e.g., a DIN connector) that couples the port to tubing of an extracorporeal circuit of a hemodialysis system. To this end, a locking device may engage both a DIN connector and a portion of the dialyzer, such as the cap or an adapter engaged therewith. The locking device may include an interior void sized and shaped to accommodate winged portions (or other portions) of the DIN connector to mitigate rotation thereof relative to the port to which it is engaged. Further, the locking device may be used to ensure that coupling between the DIN connector and the port is proper and secure. In this manner, a locking device can mitigate leaks, which can be catastrophic during a hemodialysis treatment or the like.
A dialysis machine includes a user interface for providing visual information and/or spoken information to a user. For example, in some implementations, the user interface may be configured to provide visual information related to an action, such as showing the action being partially or fully completed, and a speaker can provide spoken instructions to assist the user in machine set-up, calibration and/or operation. Such instructions can be particularly useful in a home dialysis setting. In some implementations, the speaker can provide spoken alarms that are related to alarm conditions. The spoken alarms may include patient and/or dialysis machine identifying information. The verbosity of the spoken instructions and/or the spoken alarms may be adjustable, and both may be accompanied by visual information displayed by the dialysis machine (e.g. visual alarms, images and/or video).
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
7.
DETECTING AND MONITORING OXYGEN-RELATED EVENTS IN HEMODIALYSIS PATIENTS
The present teachings include analyzing oxygen saturation levels sensed during a hemodialysis treatment for a patient to determine whether the patient has a medical condition based on hypoxemia, apnea, or the like experienced during the treatment. To this end, the present teachings may include the use of a machine-learning algorithm trained to identify a presence of a high-frequency intermittent pattern that would be formed in a plot of the oxygen saturation levels, e.g., to determine a severity of respiratory instability experienced. The present teaching may also or instead include a time-series analysis including at least one of: (i) calculating recurrence-based quantification, such as, but not limited to, recurrence rate, determinism, and laminarity; (ii) calculating the optimal recurrence threshold based on maximum variations of the system's determinism and degree of predictability; and (iii) calculating complexity-based measures such as permutation entropy. Such analyses may be used to detect, inter-alia, sleep apnea syndrome.
A device for measuring conductivity of a fluid. The device including a chamber and at least two electrodes. The chamber includes an inlet, an outlet, an upper surface, and a lower surface that runs separate from the upper surface. The fluid enters the chamber through the inlet and flows out of the chamber through the outlet. Moving along a length of the chamber from the inlet to the outlet or from the outlet to the inlet, a distance between the upper surface and the lower surface changes in at least one dimension of the chamber. The two electrodes are configured to measure electrical voltage in the fluid that enters the chamber through the inlet and flows out of the chamber through the outlet.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
9.
System and a Computer-Implemented Method for Detecting Medical-Device Errors by Analyzing Acoustic Signals Generated by the Medical Device's Components
A system includes a sensor element arranged to detect a spectrum of noise or vibrations of a medical device to be supervisedthe, a supervising element, whereby the sensor element and the supervising element may communicate with each other and thereby allow for provisioning of data corresponding to the acoustic signals, whereby the system further comprises a localized or distributed detection engine, the detection engine analyzing the data corresponding to the acoustic signals such that typical failures of each of a plurality of individual components of the medical device are distinguished, whereby the system further comprises a notification engine, the notification engine providing indications on the maintenance state of the medical device and/or one or more of the plurality of individual components of the medical device. The disclosure also pertains to a computer-implemented method for determining a maintenance state of a medical device.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
A method of monitoring a medical treatment device includes detecting a sound of the medical treatment device with a detection device, determining whether the sound is an irregular sound, and deploying an intervention upon determining that the sound is the irregular sound.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
Computer code embedded in an electronic component (e.g., a processor, a sensor, etc.) of a medical device, such as a dialysis machine, can be authenticated by comparing a metadata signature derived from the computer code of the electronic component to a key derived from a pre-authenticated code associated with the electronic component. The metadata signature can be derived by running an error-check/error-correct algorithm (e.g., SHA256) on the computer code of the electronic component. A use of the metadata signature enables detection of any unauthorized changes to the computer code as compared to the pre-authenticated code.
H04L 9/32 - Arrangements for secret or secure communications; Network security protocols including means for verifying the identity or authority of a user of the system
H04L 9/30 - Public key, i.e. encryption algorithm being computationally infeasible to invert and users' encryption keys not requiring secrecy
H04L 9/14 - Arrangements for secret or secure communications; Network security protocols using a plurality of keys or algorithms
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
12.
Managing Communications With A Connected Health System
A medical system, comprising: a medical machine; and a gateway device configured to communicate with the medical machine to allow access to a network, the gateway device comprising a data allowance and limitation unit that is configured to limit communication between the medical machine and the network when the data allowance and limitation unit is in an open state, wherein the data allowance and limitation unit is placed in the open state when a plannable system event occurs, and wherein, while in the open state, the data allowance and limitation unit is placed in a closed state when an unplanned event occurs, thereby providing less limited communication between the medical machine and the network compared to the open state.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
H04L 12/66 - Arrangements for connecting between networks having differing types of switching systems, e.g. gateways
H04L 67/10 - Protocols in which an application is distributed across nodes in the network
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
The present teachings generally include parabiotic dialysis systems and techniques. For example, the present disclosure includes parabiotic liver dialysis, e.g., for use in settings with limited resources. To this end, a parabiotic liver dialysis system may include a device having a semipermeable membrane with an average pore size that allows for the passage of albumin therethrough. In such a system, a first extracorporeal circuit may connect the device to the vascular system of a first animal (e.g., a liver patient), and a second extracorporeal circuit may connect the device to the vascular system of a second animal (e.g., a human with normal liver function), where the exchange of albumin therebetween is facilitated through the device. The present disclosure also includes various safety measures for parabiotic dialysis systems and techniques, such as biometric verification systems and techniques.
The present teachings include techniques for securing a connection to a dialyzer or the like—e.g., securing the junction between a dialyzer port and a connector (e.g., a DIN connector) that couples the port to tubing of an extracorporeal circuit of a hemodialysis system. To this end, a locking device may engage both a DIN connector and a portion of the dialyzer, such as the cap or an adapter engaged therewith. The locking device may include an interior void sized and shaped to accommodate winged portions (or other portions) of the DIN connector to mitigate rotation thereof relative to the port to which it is engaged. Further, the locking device may be used to ensure that coupling between the DIN connector and the port is proper and secure. In this manner, a locking device can mitigate leaks, which can be catastrophic during a hemodialysis treatment or the like.
Augmented reality-based training and troubleshooting is described for medical devices. An electronic mobile device can be equipped with an AR application that, when executed, causes the electronic mobile device to provide augmented reality-based training on how to set up, or perform maintenance on, one or more components of a medical device. The AR application, when executed, can also cause the electronic mobile device to provide augmented reality-based troubleshooting for one or more components of a medical device.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G06V 20/20 - Scenes; Scene-specific elements in augmented reality scenes
The described technology may include treatment processes to increase the red blood cell (RBC) population of individuals, particularly chronic kidney disease (CKD) patients with renal anemia, by reducing an amount of Piezo1 chemical agonists in the blood of patients. In one embodiment, a method of treating a patient with renal anemia may include increasing RBC lifespan of an RBC population of the patient via reduction of a Piezo1 channel activation duration of at least a portion of the RBC population by reducing an amount of a target uremic compound in the blood of the patient, the target uremic compound having a form that prolongs the Piezo1 channel activation duration, wherein the amount of the target uremic compound may be reduced via selectively removing at least a portion of the target uremic compound from the blood of the patient. Other embodiments are described.
A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that enables the dialysis machine to automatically identify the connections made by a user in preparation for treatment. A smart connector is disclosed that uses a split RFID device that is operational when a first portion of the connector is mated to a second portion of the connector, and is not operational when the first portion is disconnected from the second portion. In an embodiment, the split RFID device incorporates an RFID chip in the first portion of the connector and an antenna in the second portion of the connector. In an embodiment, the RFID chip can store a tag that encodes information that indicates a formulation or a volume of a dialysis bag connected to the ports of a disposable cassette such that the dialysis machine can automatically discover the configuration of the dialysis setup.
A dialysis machine comprising: a power supply for providing power to the dialysis machine, the power supply including a power supply cable that includes a first ground wire electrically connected to a first ground prong; and a hydraulics system for making dialysate, supplying the dialysate to a dialysate circuit, and draining spent dialysate from the dialysate circuit, the hydraulics system including a hydraulics grounding cable that includes a second ground wire electrically connected to a second ground prong.
H01R 13/633 - Additional means for facilitating engagement or disengagement of coupling parts, e.g. aligning or guiding means, levers, gas pressure for disengagement only
H01R 24/76 - Two-part coupling devices, or either of their cooperating parts, characterised by their overall structure with sockets, clips or analogous contacts and secured to apparatus or structure, e.g. to a wall
H01R 24/78 - Two-part coupling devices, or either of their cooperating parts, characterised by their overall structure with sockets, clips or analogous contacts and secured to apparatus or structure, e.g. to a wall with additional earth or shield contacts
19.
System for tailoring dialysis treatment based on sensed potassium concentration, patient data, and population data
A dialysis system is provided that includes a dialysis machine and a potassium sensing device that is configured to measure the concentration of potassium in the patient's blood, in spent dialysate resulting from treating the patient, or in both. The potassium sensing device can be configured to generate a sensed value of the concentration of potassium. A control and computing unit, including a processor and a memory, is configured to receive the sensed value, compare the value with one or more values stored in the memory, and generate a control signal based on the comparison. A potassium infusion circuit uses the control signal to infuse supplemental potassium solution into the treatment dialysate, a replacement fluid, or both. The memory can include stored patient-historical and population data.
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
G01J 1/00 - Photometry, e.g. photographic exposure meter
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/63 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 27/333 - Ion-selective electrodes or membranes
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G01N 21/33 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
G01N 21/62 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
Medical devices and peripheral devices can be configured to wirelessly communicate with each other and other devices through a connection between the devices. Peripheral devices may include weight scales, blood pressure monitors and/or other medical components that may be used in connection with measuring patient information related to a medical treatment by a medical device, such as a dialysis treatment performed by a dialysis machine. A medical function/data transfer device according to the system described herein may include multi-function capabilities to provide for a medical monitoring or treatment function as well as a data transfer function for transferring data between interconnected medical devices.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
Systems and methods for the image-based determination of the fluid status of a patient are described. In one example, an apparatus may include at least one processor and a memory coupled to the at least one processor. The memory may include instructions that, when executed by the at least one processor, may cause the at least one processor to receive an image that may include at least one image of a portion of a patient, determine fluid status information for the patient by processing the image via a trained computational model, the trained computational model trained based on at least one training image of the patient and a corresponding physical measurement of fluid status, the fluid status information indicating a current fluid status of the patient, and determine a treatment recommendation for the patient based on the fluid status information. Other embodiments are described.
Fresenius Medical Care Deutschland, GMBH (Germany)
Inventor
Cherif, Alhaji
Galuzio, Paulo Paneque
Kotanko, Peter
Klewinghaus, Juergen
Thompson, David
Abstract
The described technology may include processes to model acid-base homeostasis in normal patients and under acid-base disorder conditions. In one embodiment, a method may include an acid-base homeostasis analysis process. The method may include, via a processor of a computing device, providing an acid-base model configured to model acid-base homeostasis of a patient, the acid-base model comprising a patient model, a dialyzer model, and an extracorporeal CO2 removal device (ECCO2RD), and determining predicted patient information using the acid-base model. Other embodiments are described.
A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that is used to isolate individual fluid lines attached to a disposable cassette. The PD machine can include an interface for a disposable cassette, a plurality of safety mechanisms, and a processor. A plurality of fluid lines are connected to the disposable cassette, and each safety mechanism corresponds to a particular fluid line in the plurality of fluid lines. The processor is configured to detect a hazard condition, such as a loss of power to the PD machine or leak in the disposable cassette, and activate one or more safety mechanisms to isolate corresponding fluid lines connected to the disposable cassette. In one embodiment, the safety mechanisms are spring-loaded clamping mechanisms configured to compress a distensible tube connected to the fluid line. In another embodiment, the safety mechanisms include relay solenoids and/or check valves.
A secure artificial intelligence (AI) enabled wearable medical sensor platform is used for adaptive operation according to features and techniques described herein. Operational parameters are modified based on data inputs thereto that provide feedback to the AI systems of the wearable sensor platform. The described technology can facilitate adaptive optimizations provided by AI machine learning algorithms in a manner that can beneficially assist in the monitoring and treatment of a patient. For example, the system described herein may be used for the continuous monitoring of the physiological parameters and health of a patient's vascular access point (for example, the fistula) and may provide, among other things, early warnings of possible infection at the vascular access location.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
G16H 70/60 - ICT specially adapted for the handling or processing of medical references relating to pathologies
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
H04W 12/033 - Protecting confidentiality, e.g. by encryption of the user plane, e.g. user’s traffic
G08B 5/22 - Visible signalling systems, e.g. personal calling systems, remote indication of seats occupied using electromagnetic transmission
A method includes, after an extracorporeal blood treatment, connecting a fluid source to an access line that is connected to a patient, and delivering a fluid from the fluid source to the access line to infuse blood from the access line to the patient, wherein the fluid delivered to the access line has a temperature from about 30 degrees Celsius to about 38 degrees Celsius.
Described herein are computer systems and methods for generating, in silico, one or more virtual patients. The one or more virtual patients can be used, for example, to conduct a virtual clinical trial, such as to determine an efficacy of a therapy or medical device. The one or more virtual patients mathematically represent a physiological system in an actual patient for a health condition. Also, the one or more virtual patients can be used, for example, to determine an adverse effect from a therapy or any other deviation from a therapy, or compliance of a patient suffering from a health condition on a therapeutic protocol.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
27.
MEDICAL DEVICE INCLUDING AN ULTRASONIC EMITTER FOR INFESTATION AVOIDANCE
A medical device configured to prevent bug infestation is disclosed. The medical device may be a dialysis machine (e.g., a peritoneal dialysis machine) for conducting dialysis treatments. The medical device (e.g., dialysis machine) including an ultrasonic generator and emitter arranged and configured to emit an ultrasonic high frequency sound to prevent bug infestation.
A computer-implemented medical system is provided. The system includes a docking station and a mobile machine. The system is configured to perform operations comprising: receiving, by the mobile machine and from a user, a request to transport the mobile machine to a target location to perform a medical treatment; automatically navigating the mobile machine to the target location; performing, by the mobile machine, the medical treatment on a patient; determining, by the mobile machine, that the medical treatment is completed and the mobile machine is disconnected from the patient; automatically navigating the mobile machine to a stationary docking station of the medical system; and determining that the mobile machine is connected to the docking station through one or more connectors, and in response, receiving, by the mobile machine, at least one of an electrical charge, a refill of one or more supplies, a cleaning, or a drain of waste.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A system and method is provided for generating simulated dialysis treatment files. For instance, a computing device may obtain information such as general patient information, dialysis prescription information, and dialysis treatment information. The computing device may generate a dialysis treatment file based on the obtained information, and use the dialysis treatment file to verify and test an enterprise system. For instance, the generated dialysis treatment file may be used to ensure the enterprise system is functioning properly.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A dialysis system (e.g., a hemodialysis (HD) system) can be designed to operate in alternative environments, such as disaster relief settings or underdeveloped regions. The dialysis system can include a solar panel for generating electricity to power the dialysis machine and an atmospheric water generator for extracting water from ambient air. The extracted water can be used to generate dialysate and saline on-site. One or more of the components of the dialysis machine can be discrete components that are configured to facilitate fast shipping and simple on-site assembly (e.g., at a remote location). In some implementations, the discrete components may be configured to be attached to an existing dialysis system (e.g., a dialysis system designed for operation in a traditional environment) to permit the dialysis system to operate in an alternative environment.
H02S 10/10 - PV power plants; Combinations of PV energy systems with other systems for the generation of electric power including a supplementary source of electric power, e.g. hybrid diesel-PV energy systems
H02S 40/38 - Energy storage means, e.g. batteries, structurally associated with PV modules
B01D 5/00 - Condensation of vapours; Recovering volatile solvents by condensation
H02J 7/35 - Parallel operation in networks using both storage and other dc sources, e.g. providing buffering with light sensitive cells
A dialysis system includes a sorbent device positioned along a fluid circuit for regenerating dialysate during a dialysis treatment carried out at the dialysis system, a filter coupled to an outlet of the sorbent device such the any fluid flowing through the sorbent device must first flow through the filter before reentering the fluid circuit, and a pump positioned downstream of the filter along the fluid circuit. The pump is operable between first and second dialysis treatments carried out at the dialysis system to circulate a fluid through the sorbent device to prevent matter within the sorbent device from solidifying and circulate the fluid through the filter to remove contaminants from the fluid.
A prosthetic abdomen for peritoneal dialysis training is provided. The prosthetic abdomen has an inner layer of material, an outer layer of material, and a pouch formed between the inner layer of material and the outer layer of material. The outer layer of material has an inner surface partially defining the pouch, and an outer surface having a skin tone color. The positioning of the belt and skin tone color can be selected to mimic the actual peritoneum of a patient. The pouch is expandable. A method of training a patient to carry out a peritoneal dialysis self-treatment, using the prosthetic abdomen, is also provided.
This disclosure relates to remote control of dialysis machines. In certain aspects, a method includes receiving a request for a network connection from a dialysis machine and establishing the network connection with the dialysis machine. The method also includes receiving, from a client device, a request to access the dialysis machine, authorizing the client device to access the dialysis machine, receiving, from the dialysis machine, information pertaining to an operation of the dialysis machine, and providing, to the client device, the received information.
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
H04L 67/125 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks involving control of end-device applications over a network
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a pressure sensor mounted at a proximal end of a patient line made of a distensible material that provides PD solution to a patient through a catheter. During treatment, an occlusion can occur at different locations in the patient line and/or the catheter. When an incremental volume of additional solution is provided to the patient line while the occlusion is present, a change in pressure results. The change in pressure depends on the dimensions and the distensibility of the non-occluded portion of the patient line. If the change in pressure, the incremental volume, the properties related to the distensibility of the patient line, and some of the dimensions of the patient line are known, the location of the occlusion can be inferred. The occlusion type can be inferred based on the determined location.
In one aspect, a valve includes an interior channel for permitting a fluid to flow through the valve and an opening to the interior channel, the opening including a circular portion and a tapered portion adjacent the circular portion, the tapered portion having a maximum width that is less than a diameter of the circular portion, wherein the valve is rotatable about a central axis of the valve to adjust a position of a cross-sectional area of the opening with respect to a cross-sectional area of an inlet fluid line positioned to deliver the fluid to the rotary valve.
A61M 1/26 - Dialysis systems; Artificial kidneys; Blood oxygenators with membranes which are moving
F16K 1/14 - Lift valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with ball-shaped valve members
F16K 5/04 - Taps or cocks comprising only cut-off apparatus having at least one of the sealing faces shaped as a more or less complete surface of a solid of revolution, the opening and closing movement being predominantly rotary with plugs having cylindrical surfaces; Packings therefor
Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. In one embodiment, a method for determining a displacer compound may include constructing a plurality of target protein quantitative structure-activity relationship (QSAR) models, one for each of the plurality of binding sites, analyzing a set of candidate compounds using the plurality of QSAR models to determine a set of at least one potential compound with an affinity for binding to each of the plurality of binding sites, and selecting at least one displacer compound from the set of at least one potential compound. Other embodiments are described.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A system and method is provided for training operators (e.g., users), including new nurses or nephrologists as well as patients or their family members, to learn the intricacies of dialysis (e.g., hemodialysis) treatment through a simulation. The simulation may afford users the ability to fail catastrophically in simulated dialysis treatment, see the consequences, learn and internalize complex algorithms, and develop the ability to think in a time pressured situation. The simulation may thereby provide a safe learning environment for experiencing decisions and consequences of these decisions when performing a dialysis treatment. In some instances, the simulation may be in a mobile application form factor to encourage more ubiquitous use on personal devices, which may provide ease of access for the dialysis training. The simulation may further include time-based simulated scenarios that increase in difficulty and complexity between levels.
A dialyzer housing manufacturing system includes a molding device configured to mold a dialyzer housing, and a tool coupled to a robotic arm and configured to retrieve the dialyzer housing from the molding device after the dialyzer housing is molded. The tool includes a frame, a first suction cup connected to a first portion of the frame, and a second suction cup connected to a second portion of the frame, the second suction cup being oriented about 70 degrees to about 110 degrees relative to the first suction cup.
The present invention relates to a hemostasis band, comprising a band, preferably made from an elastic material, a pressure focusing element for focusing pressure generated by the band to hold a cannula in place at a cannulation point, wherein the band can be arranged in a loop and the size of the loop formed by the band is adjustable to at least one defined size by means of an external tool, such as a torque driver. Another aspect of the invention relates to a system of a hemostasis band and an external tool.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
41.
PERSONALIZED PERITONEAL DIALYSIS TREATMENT USING DESIGN OF EXPERIMENT TECHNIQUES
Fresenius Medical Care Deutschland, GMBH (Germany)
Inventor
Maheshwari, Vaibhav
Chamney, Paul
Eberle, Bernd
Abstract
The described technology generally includes systems and processes for a PD optimization process may operate to estimate, predict, or otherwise determine the value of PD dose variables values based on patient characteristics and/or PD prescription information. In one embodiment, a PD optimization process may be or may include a UFV determination process, operative to determine a predicted UFV for a patient. In some embodiments, the UFV determination process may include training a computational model to generate a predicted UFV output based on input of patient characteristics, PD prescription information, PD outcomes (for instance, UFV), and/or historical information associated with patient characteristics, PD prescription information, and/or PD outcomes. In some embodiments, a feedback control process with continuous Intraperitoneal Pressure (IPP) and hydration status measurements may be used to keep the hydration status of the patient within a target level ran. Other embodiments are described.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
42.
Determining a Volume of a Container for Dialysis Treatment
A method includes receiving, by a processor of a dialysis machine, a dialysate flow rate, a bicarbonate setting value, a signal from a pressure sensor configured to measure a pressure within a container, and a signal indicating a state of a fill valve; determining, based on the signal received from the pressure sensor and the state of the fill valve, fill parameters; determining a volume of the container based on at least two of the fill parameters; determining a depletion time in which the concentrate will be depleted from the container based on the volume of the container, the dialysate flow rate, and the bicarbonate setting value; determining, based on the depletion time, an amount of time remaining before the concentrate will be depleted from the container; and causing the dialysis machine to indicate the amount of time remaining before the concentrate will be depleted from the container.
G01F 22/02 - Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for involving measurement of pressure
G01F 9/00 - Measuring volume flow relative to another variable, e.g. of liquid fuel for an engine
In one aspect, a peritoneal dialysis (PD) system includes a housing that receives a disposable cassette, a plurality of pinch valves that receive respective sections of fluid tubing of the disposable cassette, an air port that forms an airtight seal with an air line of the disposable cassette, an air pump that alternatingly pushes air out of the air port and pulls air in from the air port, and a computer processor that controls the plurality of pinch valves and the air pump such that the cassette performs a dwell phase in which the diaphragm pump pumps fresh dialysate from a dialysate bag to a heater bag, a fill phase in which the diaphragm pump pumps the fresh dialysate from the heater bag to a patient line, and a drain phase in which the diaphragm pump pumps spent dialysate form the patient to a drain.
Compounds, systems, kits, methods, and/or apparatuses may be operative to reduce amyloid beta (Aβ) peptide in a patient, including a central nervous system (CNS) of the patient and/or a periphery (non-CNS portion) of the patient. In some embodiments, a displacer fluid comprising a Aβ displacer may be introduced to the patient to bind to a blood protein, such as albumin, that binds Aβ (for instance, Aβ peptide or non-plaque Aβ) in the patient periphery. Binding of the displacer to the blood protein may facilitate more free Aβ peptide (for instance, Aβ monomers) in the periphery for clearance via natural processes, such as through the liver or kidneys, and/or artificial processes, such as dialysis. Increased removal of the free Aβ peptide in the periphery may ultimately lead to less Aβ peptide in the CNS, which may decrease Aβ plaque formation in Alzheimer's Disease (AD) patients. Other embodiments are described.
A hemodialysis system including one or more ultraviolet chambers is disclosed. The hemodialysis system including a dialyzer arranged and configured to filter a patient's blood, a hemodialysis machine arranged and configured to pump, move, or the like dialysate through the dialyzer, the hemodialysis machine including an outlet valve and an outlet fluid flow path to pump or move dialysate from the hemodialysis machine to the dialyzer, and an inlet valve and an inlet fluid flow path to pump or receive dialysate from the dialyzer, and one or more ultraviolet chambers arranged and configured to kill bacteria, viruses, or a combination thereof. Thus arranged, by incorporating one or more ultraviolet chambers in strategic areas of the system, the ultraviolet chambers may eliminate, or at least greatly reduce, the possibility of cross-contamination in, for example, the dialysate, and thus eliminate the need for disinfecting the system between treatments.
The exemplary embodiments may provide a software tool that enables a software designer to derive a color from a reference color. The software designer may specify changes in color characteristics that are to be applied to the reference color to derive the desired color. The user interface may be provided to allow the software designer to enter information regarding the reference color and the desired changes in color characteristics. The user interface may display the reference color and that resulting desired color so that the software designer may get a visual appreciation for the difference in the colors. The software tool of the exemplary embodiments may also include a color palette generator. The color palette generator may generate a palette of colors from a reference color.
G06F 8/38 - Creation or generation of source code for implementing user interfaces
G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
G06F 3/0484 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
47.
Injection site with trifurcated connector attached to a fluid bag
A medical wetness sensing device includes a base adapted to be disposed on a wearer of the medical wetness sensing device. The base includes a first electrical conductor and a second electrical conductor electrically insulated from the first electrical conductor. The first electrical conductor includes a hinge portion enabling a first portion of the first electrical conductor to deflect, at the hinge portion, relative to a second portion of the first electrical conductor. The medical wetness sensing device includes a controller electrically connected to the first electrical conductor and the second electrical conductor. The controller is configured to detect a presence or an absence of a medical fluid electrically connecting the first and second electrical conductors.
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61F 13/00 - Bandages or dressings; Absorbent pads
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
G01M 3/16 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means
49.
Remote monitoring and control of treatment parameters on a medical device
A method comprising: establishing a wireless connection between a first medical device and a second medical device, comprising: receiving, by the first medical device, via a short-range wireless technology protocol, connection information related to the second medical device; and establishing, by the first medical device, a wireless connection with the second medical device based on the connection information.
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
H04B 5/00 - Near-field transmission systems, e.g. inductive loop type
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
This disclosure relates to dialysis systems and methods. In some implementations, a dialysis system includes a dialysis machine with a fluid line and a drain line, a blood line set configured to be connected to the dialysis machine, and a drain apparatus coupled to the dialysis machine. The drain apparatus includes a chamber configured to receive an end of a patient line of the blood line set, an inlet line, an outlet line, and a valve. The inlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the fluid line of the dialysis machine. The outlet line has a first end configured to be coupled to the chamber and a second end configured to be coupled to the drain line of the dialysis machine. The valve is configured to control flow of fluid through the outlet line.
Techniques for monitoring intraperitoneal volume (IPV) during a dwell period of a peritoneal dialysis patient include monitoring intraperitoneal pressure (IPP) during the dwell period using a pressure sensor, monitoring the density of the dialysate during the dwell period, and determining a change in IPV based at least on a change in IPP and a change in the density of the dialysate during the dwell period.
Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a dialysis machine for transferring dialysate to a patient from a dialysate source. The dialysate may flow from the dialysate source through a cartridge or cassette (e.g., a disposable cartridge or cassette) positionable within the dialysis machine. The cassette includes a fluid flow channel. The dialysis machine includes a heating chamber for in-line heating of the dialysate in the fluid flow channel. The fluid flow channel is arranged and configured to provide turbulent flow of the dialysate through the fluid flow channel to provide increased heat transfer from the heating chamber to the dialysate.
A method includes flowing spent dialysate through a spent dialysate line of a dialysis system into a fluid receptacle fluidly coupled to the spent dialysate line, reacting the spent dialysate with a chemical reagent contained within the fluid receptacle to generate a reacted sample, emitting electromagnetic radiation through the reacted sample using an emitter; detecting a level of one or more waste products present in the spent dialysate using a spectroscopy sensor positioned proximate the fluid receptacle.
A leak detector is provided that is incorporated into the wheels of a moveable medical device and/or cart or cabinet therefor. By incorporating a leak detector into the wheels themselves of the movable medical device, the leak detector, despite movement of the medical device, is suitably located to locate leaks with respect to the medical device at all times and requires no additional setup. The leak detector can further be tested by and interface with the moveable medical device to ensure the leak detector is in working condition and provide a convenient interface for a user. Additionally, by using this technology on each of the multiple wheels of a moveable medical device, the detectable area may be bigger than a leak detector at only one location.
The present teachings may generally include a first fluid connector that includes a first body having a first central cavity that defines a first fluid pathway and a first seal within the first central cavity. The first seal includes a pair of first interfacing elements positioned adjacent one another at a distal end of the first seal and a first opening configured to remain sealed closed when the first interfacing elements are adjacent, and the first opening opens when the first interfacing elements are separated. The first connector is configured to fluidly connect to a second connector by engaging the first interfacing elements and with a pair of second interfacing elements of the second connector, thereby causing both pairs of first and second interfacing elements to separate causing the opening of first opening and second opening.
A detector assembly configured for use in a dialysis (e.g., a hemodialysis) system is disclosed herein. The detector assembly including a wetness detector configured to detect blood, fluid, a leak, etc. The detector assembly being operatively coupled to, and more preferably, including an inertial measurement unit (IMU). Thus arranged, the detector assembly is configured to measure, read, obtain, provide, etc. additional information or data during a dialysis treatment, which information or data can be transmitted and/or used to, for example, provide greater insight into the system and/or to make better decisions. In one embodiment, the detector assembly can be used to determine when and how a patient is moving and feed that information back to the dialysis machine. In use, the information or data can be used in combination with other information to make an improved determination as to the requirement for an alert and/or stoppage of the dialysis treatment.
In some embodiments, a medical system includes a dialysis machine having at least one outer surface to be disinfected at a given location, at least one disinfection sensor connected to the dialysis machine at the given location, the disinfection sensor including two or more electrode in fluid contact with the outside surface of the dialysis machine, and a conductivity sensor component in electrical contact with the two or more electrodes, the conductivity sensor component configured to send an electrical signal indicating a conductivity of a liquid on an outside surface of the dialysis machine and in contact with the two or more electrodes, a processor configured to receive the electrical signal and thereby determine a disinfection status of the given location, and a user interface configured to indicate the disinfection status of the given location.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
59.
TECHNIQUES FOR DETERMINING CALCIMIMETIC DRUG ACTIVITY
The described technology may include processes to model parathyroid gland (PTG) functionality and/or calcimimetic administration to healthy subjects and/or patients with a health abnormality that affects PTG function. In one embodiments, a computer-implemented method of calcimimetic analysis of PTG functionality may include accessing a calcimimetic model configured to simulate a functionality of a PTG of at least one patient, the calcimimetic model comprising at least one of a pharmacokinetic model or a pharmacodynamic model, providing a calcimimetic administration of a calcimimetic to the at least one patient via the calcimimetic model according to an administration process, and determining calcimimetic information based on the calcimimetic administration via the calcimimetic model for the at least one patient, the calcimimetic information configured to indicate an efficacy of the calcimimetic administration. Other embodiments are described.
G16C 20/30 - Prediction of properties of chemical compounds, compositions or mixtures
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
60.
DEVICES AND METHODS FOR LATERAL FLOW TESTS OF BODILY FLUIDS
The disclosed devices for lateral flow testing may include a receptacle for receiving bodily fluids from a patient that has a predetermined fluid volume for application to one or more lateral flow test strips. A test strip holder may be positioned to receive the predetermined fluid volume of the bodily fluids from the receptacle. Various other components, devices, and methods are also disclosed.
A method and system for determining a patient's risk of developing an infection is disclosed. In one embodiment, the system and method includes extracting patient data from one or more databases corresponding to a pool of patients receiving treatment; using one or more predictive models with the extracted patient data to generate, for each of the patients in the pool of patients, a respective patient risk score for developing an infection within a selected time period; generating a report including at least a portion of the identified subset of the pool of patients and their respective patient risk scores; and transmitting the report to one or more health care facilities, the one or more health care facilities further identifying one or more patients from the portion of the identified subset of the pool of patients for interventional treatment, consultation, training, or combinations thereof.
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
In one aspect, a valve actuation system includes a drive unit including an actuator configured to engage and move multiple valves disposed within a fluid cassette to selectively open and close each valve of the multiple valves and a positioning frame disposed adjacent the fluid cassette and along which the drive unit can be moved in three dimensions to align the actuator with a selected valve of the multiple valves.
G05D 7/06 - Control of flow characterised by the use of electric means
A61M 1/26 - Dialysis systems; Artificial kidneys; Blood oxygenators with membranes which are moving
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
F16K 31/04 - Operating means; Releasing devices magnetic using a motor
F16K 11/20 - Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves; Arrangement of valves and flow lines specially adapted for mixing fluid with two or more closure members not moving as a unit operated by separate actuating members
A computer-implemented method, a medical device, and a system for acquiring user-specific customization data, i.e. user-specific language packages, are provided. The computer-implemented method comprises: determining a first set of user-specific customization data stored on the medical device; comparing the first set of user-specific customization data with a second set of user-specific customization data that is required by a user; and upon determining that the second set of user-specific customization data is different from the first set of user-specific customization data, acquiring, from a data storage external to the medical device, the second set of user-specific customization data or a delta between the first set and the second set of user-specific customization data.
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
H04L 29/06 - Communication control; Communication processing characterised by a protocol
65.
MEDICAL FLUID DRAIN CONTAINERS AND RELATED SYSTEMS AND METHODS
A method includes collecting used dialysis fluid in a container and combining the dialysis fluid with an acid to lower the pH value of the used dialysis fluid.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
In one aspect, a system includes a blood treatment machine; a dialyzer configured to be coupled to the blood treatment machine, the dialyzer including a dialyzer housing defining a blood inlet and a blood outlet; a bundle of hollow fibers within an interior of the dialyzer housing; a pumping device drivable to force blood received from the blood inlet through lumens of the bundle of hollow fibers and out the blood outlet; a dialysate inlet port in fluid communication with a dialysate flow path that includes space in the interior of the dialyzer housing between the bundle of hollow fibers; and a dialysate outlet port in fluid communication with the dialysate flow path. The system further includes a fluid conditioning system configured to (i) prepare and supply fresh dialysate to the dialyzer via the dialysate inlet port, and (ii) receive spent dialysate from the dialyzer via the dialysate outlet port, recycle the spent dialysate, and supply the recycled dialysate to the dialyzer via the dialysate inlet port.
A dialysis system includes include a home dialysis machine and a home gateway device in communication with a cloud-based application via a connected health system. The gateway device has voice recognition capabilities. A user can provide spoken information to the gateway device, and the gateway device can cause one or more actions to be performed. The gateway device may cause a dialysis function to be performed by the dialysis machine, or data to be input into the dialysis machine. The gateway device can also communicate with one or more other systems (e.g., remote systems) via the cloud-based application. In some examples, the cloud-based application can communicate with an order management system to allow the user to order medical supplies (e.g., for use with the dialysis machine) via the gateway device. The gateway device can provide two-way conversational capability (e.g., back and forth communication) between the user and the gateway device.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G10L 15/22 - Procedures used during a speech recognition process, e.g. man-machine dialog
This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a blood treatment system includes a user interface; a processor in communication with the user interface and configured to perform operations including: presenting instructions on the user interface, the instructions pertaining to at least one modality of a set of modalities, wherein the set of modalities include hemodialysis (HD), hemofiltration (HF), and hemodiafiltration (HDF), wherein the instructions pertain to a component of a blood treatment machine of the blood treatment system; receiving information associated with the component of the blood treatment machine; and eliminating modalities from the set of modalities to determine a modality of the blood treatment machine based on the received information.
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
69.
Techniques for removing bound target substances during dialysis
Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to access dialysis information for a dialysis process performed by a dialysis machine, the dialysis information indicating a target substance to be displaced from a binding compound by a displacer, and determine an infusion profile for infusing the displacer into a patient during a displacer infusion process of the dialysis process, the infusion profile determined based on the dialysis information and an infusion constraint. Other embodiments are described.
G06F 9/30 - Arrangements for executing machine instructions, e.g. instruction decode
G06F 15/16 - Combinations of two or more digital computers each having at least an arithmetic unit, a program unit and a register, e.g. for a simultaneous processing of several programs
The described technology may include processes to model renal pathophysiology in patients and/or patient populations. In one embodiment, a method may include a CKD/ESRD condition analysis, such as a vascular calcification analysis. The method may include, via a processor of a computing device: determining a vascular calcification model configured to model vascular calcification of a virtual patient to determine a causal relationship between at least one patient characteristic and a vascular calcification indicator, and generating a causal relationship structure configured to visualize a causal relationship between the at least one patient characteristic and the vascular calcification indicator. Other embodiments are described.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
A medical fluid line connector includes a body defining a central opening extending therethrough, a first projection extending from a first portion of the body, and a second projection extending from a second portion of the body, the second projection being circumferentially and axially offset from the first projection. The first portion of the body and second portion of the body are configured to separate from one another in response to a threshold amount of force being applied to the first projection and the second projection to rotate the first portion of the body and second portion of the body relative to one another.
A container system includes at least one flexible wall defining a compartment containing a dissolvable solid or concentrate, a support adjacent a first end of the at least one flexible wall, and a nozzle assembly coupled to a second end of the at least one flexible wall. The second end of the wall is distal from the first end. The nozzle assembly comprises a hollow body defining a longitudinal axis. The hollow body further defines a plurality of orifices through a wall thereof. Each orifice is able to form a fluid connection between an interior volume within the hollow body and the compartment. Each orifice is configured to deliver liquid from the interior volume to the compartment in a direction having an angle of between 5° and 85° from a direction of the longitudinal axis. Related nozzles and methods are also disclosed.
This disclosure relates to symmetric tubing clamps for blood treatment systems and related systems and methods. In some aspects, a tubing clamp includes a resilient body that has symmetry with respect to a first plane with a normal along a longitudinal axis of the resilient body, the resilient body comprising a sidewall defining an opening such that a tubing is arrangeable through the opening along the longitudinal axis of the resilient body; first and second snap-fit features configured to engage with each other when the resilient body is compressed along a direction transverse to the longitudinal axis; and a protrusion configured to constrict the tubing when the resilient body is compressed along the direction transverse to the longitudinal axis.
An extracorporeal blood treatment device and a method are provided for removing a secondary membrane formed on a semipermeable membrane of a dialyzer during an extracorporeal blood treatment. The extracorporeal blood treatment device operates in a first operating mode in which a dialysate outlet valve is open such that dialysate flows through a dialyzer feed line, through a dialysate chamber, and into and through a dialyzer discharge line. The extracorporeal blood treatment device operates in a second operating mode to remove the secondary membrane from the semipermeable membrane. During the second operating mode, the dialysate outlet valve is closed for a duration of time such that dialysate is prevented from flowing through the dialyzer discharge line. A backflush procedure results wherein a volume of dialysate passes from the dialysate chamber through the semipermeable membrane and into the blood chamber.
The present invention relates to a method to make polymeric membranes that are preferably useful in dialysis, wherein the method conducts at least one membrane-forming step and/or post-forming processing step with the use of sonication. Polymeric membrane, such as polymeric hollow fiber membrane, having improved one or properties are further described.
A mechanical lift includes a housing defining a series of vertical adjustment notches, an adjustment block disposed within the housing, a hook extending from the adjustment block and configured to support a hanging load, a stopper supported by the adjustment block and movable between retracted and extended positions, and a spring disposed within the housing and exerting an upward force against the adjustment block to mechanically lift the adjustment block and the hook extending therefrom from a first vertical position at a first notch of the series of vertical adjustment notches to a second notch of the series of vertical adjustment notches when the stopper is in the retracted position. In the retracted position, the stopper is disengaged from the housing. In the extended position, the stopper is engaged with a selected notch to lock a vertical position of the adjustment block and the hook extending therefrom.
A dialysis system may include a dialysis machine (e.g., a peritoneal dialysis machine) having a fluid system for delivering fluid (e.g., dialysate) to a patient. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to determine volume information for a fluid system of a dialysis machine, wherein the volume information may comprise a patient line volume and an accuracy adjustment volume, and to determine a priming volume to prime the fluid system with a fluid based on the volume information. Other embodiments are described.
A medical treatment machine, such as a dialysis machine (e.g., a home dialysis machine, such as a home hemodialysis machine or a home peritoneal dialysis machine) can receive a digital prescription file that defines parameters of a medical treatment to be administered to a patient. The digital prescription file can be prepared and delivered in such a way that the medical treatment machine can confirm that the issuer (e.g., provider) of the digital prescription file is an authorized issuer without having any a priori knowledge of the particular issuer. The digital prescription file can be delivered irrespective of the inherent security (or lack thereof) of the transmission medium in a tamper-evident format using minimal resources necessary to verify the validity of the digital prescription file and its issuer. The digital prescription file may be delivered to the dialysis machine using a network cloud-based connected health system.
H04L 9/32 - Arrangements for secret or secure communications; Network security protocols including means for verifying the identity or authority of a user of the system
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
79.
Short-Range Wireless Communication for a Dialysis System
A dialysis system comprising: a dialysis machine; a communication module configured to communicate using a short-range wireless technology protocol; data storage configured to store data corresponding to identities of one or more short-range wireless devices; and a processor configured to: identify presence of a short-range wireless device; and cause the dialysis machine to carry out an action when one or both of i) the presence of the short-range wireless device is identified, and ii) the presence of the short-range wireless device is no longer identified.
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
80.
Prescription compatibility checking for a medical device
A medical treatment machine, such as a home dialysis machine, can receive prescription parameters that define parameters of a medical treatment to be administered to a patient. A medical prescription is entered by a clinician into a clinical information system (CIS) that calls a system to evaluate the compatibility of the entered prescription by transmitting the prescription parameters to a server that has access to a database of medical devices and their operational parameters. The server compares the treatment parameters of the medical prescription to the operational parameters of the medical device and generates a prescription compatibility response indicting if the treatment parameters of the medical prescription can be executed by the medical device. The server returns to the CIS the prescription compatibility response to allow the prescription, e.g. in a digital or program form, to be securely transmitted or delivered via a connected health system to the medical device.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G06F 3/0488 - Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
Embodiments of the disclosure provide a method for determining beginning blood volume of a patient during dialysis (e.g., hemodialysis). Ultrafiltration rates are determined at different time stamps during dialysis by obtaining a blood flowrate measurement and hematocrit measurements at input port and output port of a dialyzer connected to the patient. The flowrate and hematocrit measurements are used to determine fluid removed from the patient during dialysis. The ultrafiltration rates and fluid removed from the patient are used to determine the beginning blood volume of the patient.
In one aspect, a medical device includes: a housing; a plurality of attachment points disposed on a face of the housing and configured to hold a medical fluid tubing system; a lighting system disposed at or below the face of the housing; and a processor configured to control the lighting system to (a) visually indicate the locations of the attachment points and (b) in response to a feedback signal indicating whether or not the medical fluid tubing system is attached to at least one of the attachment points, alter the visual indication of the lighting system.
A method comprising: establishing a wireless connection between a first medical device and a second medical device, comprising: receiving, by the first medical device, via a short-range wireless technology protocol, connection information related to the second medical device; and establishing, by the first medical device, a wireless connection with the second medical device based on the connection information.
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
H04B 5/00 - Near-field transmission systems, e.g. inductive loop type
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
84.
Home dialysis supplies delivery robot, network, and method
A delivery robot is provided for the delivery of home dialysis supplies to a home dwelling of a home dialysis patient. The delivery robot can be an autonomous delivery robot. The delivery robot can have an outdoor set of wheels or other traction devices, and an indoor set of wheels or other traction devices. The delivery robot can be configured to switch between an outdoor configuration for traversing an outdoor surface, and an indoor configuration for traversing an inside surface, inside the home of the home dialysis patient. A network is also provided and can include a robot delivery vehicle, a warehouse, a remote computer within the patient's home, or a combination thereof. Methods of delivering home dialysis supplies are also provided that utilize the delivery robot and network.
G05D 1/02 - Control of position or course in two dimensions
G05D 1/00 - Control of position, course, altitude, or attitude of land, water, air, or space vehicles, e.g. automatic pilot
G07C 9/29 - Individual registration on entry or exit involving the use of a pass the pass containing active electronic elements, e.g. smartcards
B62D 61/12 - Motor vehicles or trailers, characterised by the arrangement or number of wheels, not otherwise provided for, e.g. four wheels in diamond pattern with variable number of ground-engaging wheels, e.g. with some wheels arranged higher than others, or with retractable wheels
G07C 9/10 - Movable barriers with registering means
G07C 9/22 - Individual registration on entry or exit involving the use of a pass in combination with an identity check of the pass holder
B60B 19/00 - Wheels not otherwise provided for or having characteristics specified in one of the subgroups of this group
A device for detecting potential health issues includes a retinal scanner configured to capture retinal data of the user, a blood pressure sensor configured to capture blood pressure data of the user, an alert module configured to alert the user of a potential health risk, and at least one processor communicatively coupled to the retinal scanner, the blood pressure sensor, and the alert module.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61B 5/0205 - Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
G01G 19/50 - Weighing apparatus or methods adapted for special purposes not provided for in groups for weighing persons having additional measuring devices, e.g. for height
86.
Systems for supporting medical fluid bags and related methods
This disclosure relates to systems for supporting medical fluid bags and related methods. In some implementations, a system includes a curved tray configured to support a medical fluid bag during a medical treatment, the curved tray including a plurality of openings therethrough, a medical fluid collection basin removably coupled to the curved tray and configured to collect medical fluid leaked from the medical fluid bag during the medical treatment, a leak detector coupled to a surface of the medical fluid collection basin and configured to detect fluid as leaked from the medical fluid bag into the medical fluid collection basin, and a control unit configured to receive treatment data related to the medical treatment.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
This disclosure relates to medical fluid cassette leak detection methods and devices. In some implementations, a method of detecting micro-leaks in a medical fluid cassette, the method includes decreasing a pressure between a vacuum reservoir of a medical treatment machine and a membrane of the medical fluid cassette when the medical fluid cassette is coupled to the medical treatment machine; measuring, using a flow meter, a rate of net fluid flow between the vacuum reservoir and the membrane of the medical fluid cassette; determining that the rate of net fluid flow between the vacuum reservoir and the membrane of the medical fluid cassette is above a threshold value; and in response to determining that the rate of net fluid flow is above the threshold value, causing the medical treatment machine to take a particular action.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A medical device, such as a dialysis machine, may be equipped with a focused directional speaker system and/or displays to direct audible and visual alarms towards a patient in order to minimize disruption to others caused by an alarm. The speaker system may be useful for home dialysis patients whose alarming devices at night wake up not only their partners but also neighbors, especially when the patient is hard of hearing or a heavy sleeper and needs to set the volume at the loudest setting in order to hear it. Further implementation and safety features may provide that, if the patient still does not awaken after a set amount of time to clear the alarm, then the dialysis device broadcasts the alarm to the entire room.
H04R 1/32 - Arrangements for obtaining desired frequency or directional characteristics for obtaining desired directional characteristic only
G08B 7/06 - Signalling systems according to more than one of groups ; Personal calling systems according to more than one of groups using electric transmission
A dialysis machine comprising: a power supply for providing power to the dialysis machine, the power supply including a power supply cable that includes a first ground wire electrically connected to a first ground prong; and a hydraulics system for making dialysate, supplying the dialysate to a dialysate circuit, and draining spent dialysate from the dialysate circuit, the hydraulics system including a hydraulics grounding cable that includes a second ground wire electrically connected to a second ground prong.
H01R 13/633 - Additional means for facilitating engagement or disengagement of coupling parts, e.g. aligning or guiding means, levers, gas pressure for disengagement only
H01R 13/652 - Protective earth or shield arrangements on coupling devices with earth pin, blade or socket
H01R 24/30 - Coupling parts carrying pins, blades or analogous contacts and secured only to wire or cable with additional earth or shield contacts
H01R 24/76 - Two-part coupling devices, or either of their cooperating parts, characterised by their overall structure with sockets, clips or analogous contacts and secured to apparatus or structure, e.g. to a wall
H01R 24/78 - Two-part coupling devices, or either of their cooperating parts, characterised by their overall structure with sockets, clips or analogous contacts and secured to apparatus or structure, e.g. to a wall with additional earth or shield contacts
A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.
G01M 3/32 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators
A system and method for measuring edema, at home, is provided, along with a measuring pattern for use therewith. The system includes a computing system that has an imaging device, a processor, a memory, and a wireless transmitter. The computing system is configured to capture edema data of a patient and send the data to a remote doctor. The pattern can be incorporated into a flexible sheet substrate that can be placed over a portion of a patient's skin. By pressing the flexible sheet substrate into the patient, a depression is formed and the pattern is distorted. The imaging device captures an image of the depression and the distorted pattern. The computing system processes the image and determines a depth of the depression based on the distortion of the pattern.
G06T 7/521 - Depth or shape recovery from the projection of structured light
G06T 7/70 - Determining position or orientation of objects or cameras
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
A dialysis system has a module with a dialyzer configured to remove one or more substances from a dialysis solution as it passes through a dialyzer. The module has a fluid line, a sorbent cartridge, and a sodium control system adapted to actively alter a sodium concentration of dialysis solution passing through the fluid line as the dialysis solution exits the sorbent cartridge. The sodium control system has a conductivity sensor that sends a signal indicating the conductivity of the dialysis solution as the dialysis solution exits the sorbent cartridge, the conductivity meter being in communication with the sodium control system, a processor configured to receive the signal from the conductivity sensor, compare the conductivity signal to a threshold value lower than a prescription value, and cause the sodium control system to stop actively altering the sodium concentration if the signal is greater than the threshold value.
Techniques and apparatus for generating, performing, and evaluating virtual clinical trials that include clinic modules to represent real-world operational aspects of trial entities are described. In one embodiment, for example, an apparatus may include at least one memory, and logic coupled to the at least one memory. The logic may be configured to generate a plurality of avatars configured to model a health condition associated with a population of patients, and to perform a virtual clinical trial to simulate a course of treatment for the plurality of avatars, the virtual clinical trial to include at least one clinic module associated with at least one event and a probability for the at least one event, the at least one event to model an operational aspect of an entity of the virtual clinical trial. Other embodiments are described.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A technique for determining skin sodium content using bioimpedance spectroscopy includes applying a current at a predetermined frequency to skin of a subject, measuring a voltage across the skin of the subject produced by the current, determining a resistance across the skin of the subject at the predetermined frequency using the measured voltage, and determining skin sodium content using the measured voltage.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1477 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means non-invasive
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
96.
MEDICAL DEVICE TROUBLESHOOTING USING COMPUTATIONAL MODELS
Systems and methods for device troubleshooting processes based on computational models are described. In one example, an apparatus may include at least one processor and a memory coupled to the at least one processor. The memory may include instructions that, when executed by the at least one processor, may cause the at least one processor to determine abnormal event information associated with an abnormal event active on the device, and determine, via a computational model: a diagnosis of a device problem based on the abnormal event information, and at least one resolution to resolve the device problem. Other embodiments are described.
Methods, apparatuses, and systems for determining patient dialysis profiles, for example, of peritoneal transport status or disease progression, are described. For example, in one embodiment, a method of determining a patient profile of a dialysis patient may include obtaining a volume of fluid associated with the dialysis patient, generating patient information via fluorescence analysis of the patient fluid, and determining the patient profile based on evaluating the patient information with a profile library, the patient profile comprising at least one of a peritoneal transport status classification or a disease progression. Other embodiments are described.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
98.
LIPOPOLYSACCHARIDE (LPS) APTAMERS AND ASSOCIATED METHODS
C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
99.
LIPOTEICHOIC ACID (LTA) APTAMERS AND ASSOCIATED METHODS
Described are a number of aptamers that are specific to bind with peptidoglycan (“PGN”) with specificity over counter-targets lipopolysaccharides (“LPS”) and lipoteichoic acid (“LTA”), and associated methods.
patents
