In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.
The present disclosure provides a tissue debridement device and describes an example treatment for ANP using the tissue debridement device. The tissue debridement device has a sheath, a distal tip, and a plurality of rotating tines coupled to the distal tip and the sheath. The distal tip can be adjusted to be closer or further from the sheath to change a diameter of the rotating tines, thereby changing a cutting diameter of the tissue debridement device.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
3.
ELECTRICAL STIMULATION DEVICES FOR CANCER TREATMENT
Embodiments herein relate to a medical device for treating a cancerous tumor, the medical device having a first lead including a first wire and second wire; a second lead can include a third wire and fourth wire; and a first electrode in electrical communication with the first wire, a second electrode in electrical communication with the second wire, a third electrode in electrical communication with the third wire, and a fourth electrode in electrical communication with the fourth wire. The first and third electrodes form a supply electrode pair configured to deliver one or more electric fields to the cancerous tumor. The second and fourth electrodes form a sensing electrode pair configured to measure an impedance of the cancerous tumor independent of an impedance of the first electrode, the first wire, the third electrode, the third wire, and components in electrical communication therewith. Other embodiments are also included herein.
An apposition device having a first elongate element movably coupled with a second elongate element. The second elongate element is deployable distal to the structures to be apposed, in a position transverse to the first elongate element. The first elongate element may be pulled to pull the second elongate element to move the structures into apposition. A third element may be positioned proximal to the structures to hold the structures in apposition. The third element may be a ratcheting element fixable in place with respect to the first elongate element. The apposition device may be deployed with a fine gauge needle. The second elongate element may be deployed from a side port in the needle facilitating deployment, and/or movement of the second elongate element with respect to the first elongate element and into a deployment configuration. Such arrangement may allow control of the first elongate element independent of the needle.
A61B 17/11 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for performing anastomosis; Buttons for anastomosis
An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of articulating members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
6.
DEVICES, SYSTEMS, AND METHODS FOR MOVING AND/OR HOLDING ANATOMICAL STRUCTURES IN APPOSITION
An apposition device having a first elongate element movably coupled with a second elongate element. The second elongate element is deployable distal to the structures to be apposed, in a position transverse to the first elongate element. The first elongate element may be pulled to pull the second elongate element to move the structures into apposition. A third element may be positioned proximal to the structures to hold the structures in apposition. The third element may be a ratcheting element fixable in place with respect to the first elongate element. The apposition device may be deployed with a fine gauge needle. The second elongate element may be deployed from a side port in the needle facilitating deployment, and/or movement of the second elongate element with respect to the first elongate element and into a deployment configuration. Such arrangement may allow control of the first elongate element independent of the needle.
A61B 17/04 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for suturing wounds; Holders or packages for needles or suture materials
7.
THROMBECTOMY SYSTEM INCLUDING A ROLLER PUMP ACTUATED VALVE
Thrombectomy catheter and pump assemblies for controlling a flow of effluent from a thrombectomy catheter. An illustrative assembly may a thrombectomy catheter (58), a pump (240), a connection manifold assembly (62) positioned between the thrombectomy catheter and the pump, an effluent return tube (66) fluidly coupled to the thrombectomy catheter and the connection manifold assembly, an effluent collection bag (28), an effluent waste tube (68) fluidly coupled to the connection manifold assembly and the effluent waste bag, and a spool valve (400) positioned in line with the effluent waste tube.
The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to a tissue traction device for endoscopic procedures such as tissue dissection. For example, a tissue traction device may include first and second attachment members pivotably attached by first and second swivels to opposite ends of a stretchable traction band comprising a compliant or semi-compliant material.
A61B 17/02 - Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A device for permanent placement across an atrial appendage ostium in a patient includes a support structure having a contracted delivery configuration and an expanded deployed configuration defining a radially enlarged portion to permanently engage an interior wall of the atrial appendage, a membrane attached to the support structure and configured to extend across the ostium of the atrial appendage when the support structure is in the expanded deployed configuration, and a polymer coating disposed on at least one of the support structure and the membrane, the polymer coating including a direct oral anticoagulant (DOAC) dispersed in a polymer.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61K 31/444 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
An applicator of a clip system includes an elongated member and a bushing coupled to a distal end of the elongated member and a coupling movably attached to the bushing. A capsule is coupled to the coupling via a coupling member hooked over a hook of the coupling. Proximal ends of clip arms are received within the capsule and a core member received between and connected to the proximal ends of the arms includes a projection and a failure point distal of the projection. The core member is coupled to a control member so that movement of the control member relative to the elongated member opens and closes the arms. The projection is configured so that, when the clip is clipped over tissue, the coupling is drawn into the body and the projection drives the coupling member radially outward off the hook to free the capsule.
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
An applicator of a clip system includes an elongated member and a bushing coupled to a distal end of the elongated member and a coupling movably attached to the bushing. A capsule is coupled to the coupling via a coupling member hooked over a hook of the coupling. Proximal ends of clip arms are received within the capsule and a core member received between and connected to the proximal ends of the arms includes a projection and a failure point distal of the projection. The core member is coupled to a control member so that movement of the control member relative to the elongated member opens and closes the arms. The projection is configured so that, when the clip is clipped over tissue, the coupling is drawn into the body and the projection drives the coupling member radially outward off the hook to free the capsule.
An example medical device includes a container and tube set arranged and configured to couple to an endoscope, a first gas supply, and a second gas supply for use in an endoscopic procedure. The container and tube set includes a container having an interior volume configured to contain a fluid, a gas supply tube having a first end and a second end in fluid communication with the interior volume of the container, and a coupling mechanism having a first end and a second end, wherein the first end of the coupling mechanism is configured to engage with the second end of the gas supply tube and the second end of the coupling mechanism is configured to engage with both the first gas supply and the second gas supply interchangeably.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/12 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
A61M 39/12 - Tube connectors or tube couplings for joining a flexible tube to a rigid attachment
In some aspects, the present disclosure pertains to a system for forming a radiopaque product that comprises an iodinated compound comprising one or more diene containing moieties and a multi-arm polymer comprising a plurality of dienophile containing moieties, wherein the diene containing moieties of the iodinated compound couple with the dienophile containing moieties of the multi-arm polymer through a Diels-Alder reaction. Other aspects of the disclosure pertain to crosslinked networks that are formed by combining such an iodinated compound with such a multi-arm polymer, whereupon the diene containing moieties couple with the dienophile containing moieties through a Diels-Alder reaction. Still other aspects of the disclosure pertain to methods of treatment comprising administering to a subject a mixture that comprises such an iodinated compound and such a multi-arm polymer, whereupon the diene containing moieties couple with the dienophile containing moieties by undergoing a Diels-Alder reaction after administration.
Devices, systems, and methods for coupling tubing to a fluid reservoir to provide liquid to an endoscope system. A manifold for coupling to a fluid reservoir and a tubing assembly may include first portion interfacing with an interior of the fluid reservoir and a second portion configured to interface with tubing to be fluidly coupled to the interior of the reservoir. The first portion may include one or more openings to allow gas to pass into the fluid reservoir and liquid to pass out of the fluid reservoir. The second portion may include one or more ports for connecting to tubing that brings gas to the fluid reservoir and receives liquid from the fluid reservoir. The manifold may include a valve that selectively allows gas to pass into the fluid reservoir.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/012 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor
A61B 1/12 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
15.
SYRINGE DESIGN FOR CYCLING PARTICULATE SUSPENSIONS
The present disclosure pertains to a syringe comprising: a syringe barrel having an open proximal end that opens into an interior having a cylindrical wall and an angled distal surface terminating at an outlet; a plunger rod; and a plunger seal, a proximal end of the plunger seal configured to be attached to a distal end of the plunger rod, and a distal end of the plunger seal configured to be inserted into the interior of the syringe barrel through the open proximal end, the plunger seal forming a seal with the cylindrical wall of the interior of the syringe barrel, and the distal end of the plunger seal terminating at an angled distal surface, wherein the angled distal surface of the syringe barrel is more acute than the angled distal surface of the plunger seal. The present disclosure also pertains to kits containing such a syringe.
A valve assembly for a medical device including a container including a first region and a second region, a first fluid inlet fluidly coupled to the first region, a second fluid inlet fluidly coupled to the second region, and a piston assembly disposed within the container. The container is configured to house an agent within the second region, the first fluid inlet is configured to deliver a first portion of pressurized fluid to the first region at a first pressure level, and the second fluid inlet is configured to deliver a second portion of pressurized fluid to the second region at a second pressure level that is less than the first pressure level. The piston assembly includes a valve configured to move from a first position to a second position in response to the piston assembly moving relative to the container.
A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip jaws, proximal ends of which are slidably received within the channel of the capsule so that the clip jaws are movable between an open configuration and a closed configuration. Clip jaws are configured so that a distance between the distal ends of the clip jaws in an open configuration is between 15 and 18 millimeters. Clip jaws further include barbs extending from a distal portion thereof.
A61B 17/10 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for applying or removing wound clamps; Wound clamp magazines
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
Irrigation devices, methods, and systems are disclosed. The system comprises a catheter with one or more lumens and an expandable portion. One or more pumps are used to supply a mixture of contrasting and dilating agents in an interior kidney volume and flush a portion of the mixture out of the interior kidney volume. The method comprises placing a catheter into the interior kidney volume through a ureter, occluding a portion of the ureter with a distal end of the catheter, forming an exit port through an exterior kidney surface, flowing the contrasting and dilating agents through the one or more lumens to supply the mixture in the interior kidney volume, and flushing a portion of the mixture out of the exit port.
A medical device includes an electrode shaft and an insulation tip. The electrode shaft is configured to deliver energy to a target site and includes an electrode shaft lumen configured to deliver fluid to the target site. The insulation tip is coupled to a distal tip of the electrode shaft. The insulation tip includes an insulation tip lumen fluidly connected to the electrode shaft lumen and configured to deliver fluid to the target site. The insulation tip covers an entirety of the distal tip of the electrode shaft.
The present disclosure relates generally to systems, medical devices, and methods for closing an opening in a target tissue using hydraulics and/or pneumatics. In some embodiments, a medical device may include an endoscopic device operable to close an opening in a target tissue, and an actuator operable with the endoscopic device, wherein the actuator includes a piston within a chamber. The piston may include a piston head engaged with an interior surface of the chamber, and a piston rod coupled to a tissue engagement component of the endoscopic device, wherein pressure from a fluid within the chamber actuates the tissue engagement component.
A61B 17/04 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for suturing wounds; Holders or packages for needles or suture materials
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
Thrombectomy catheter and pump assemblies for controlling a flow of effluent from a thrombectomy catheter. An illustrative assembly may a thrombectomy catheter, a pump, a connection manifold assembly positioned between the thrombectomy catheter and the pump, an effluent return tube fluidly coupled to the thrombectomy catheter and the connection manifold assembly, an effluent collection bag, an effluent waste tube fluidly coupled to the connection manifold assembly and the effluent waste bag, and a spool valve positioned in line with the effluent waste tube.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A medical device system may include an occlusive implant including a central hub and a plurality of elongate members configured to shift between extended and radially expanded configurations. The central hub includes a plurality of conduits extending from a proximal end to a radially outward facing surface. The plurality of elongate members is configured to extend through the conduits in the radially expanded configuration. An implant remodeling tool may include an elongate sheath having at least one lumen, a plunger guide, and a plurality of plunger shafts extending from the at least one lumen through the plunger guide. The plunger guide is configured to direct the plunger shafts radially outward as the plunger shafts are advanced distally. The plunger shafts are configured to engage a medical implant and urge at least a portion of the implant radially outward.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
23.
CUTTING BALLOON CATHETER WITH FLEXIBLE CUTTING BLADES
A cutting balloon catheter including a balloon mounted on a distal portion of a catheter shaft. The balloon includes a cutting member mounted on an exterior surface of the balloon which includes one or more features for providing the cutting member with enhanced flexibility for navigating tortuous anatomy and more closely conforms to the expansion characteristics of the balloon to which the cutting member is mounted.
In accordance with some aspects, the present disclosure is directed to medical compositions that comprises (a) a first hydrophilic polymer functionalized with a plurality of first functional groups and (b) a second hydrophilic polymer functionalized with a plurality of second functional groups, wherein the first and second functional groups are selected to react and form covalent bonds upon a change in conditions such that the first and second hydrophilic polymers crosslink with one another. In other aspects the present disclosure is directed to kits that comprise such medical compositions and to medical procedures that utilize such medical compositions.
A medical device system (100) may include a control unit (175) comprising one or more processors that implement an algorithm to enhance images obtained by a medical device (101). The one or more processing boards perform the steps of: receiving a first image from the first viewing element; determining a current illumination value of the first image; determining a first difference between the current illumination value and a target high illumination value if the current illumination value is greater than the target high illumination value; determining a second difference between the current illumination value and a target low illumination value if the current illumination value is less than the target low illumination value; generating a new illumination value, using at least one of the first difference and the second difference; and converting the new illumination value to a first voltage value for application to one or more illuminators of the medical device.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
26.
BEACON DEVICES, SYSTEMS, AND METHODS FOR MEDICAL PROCEDURES
A locator system having a flexible elongate delivery device, such as a flexible guidewire, advanced to a target site separately from the beacon element of the system. The beacon element may be configured to not extend beyond the perimeter of a housing on which the beacon element is mounted, thereby reducing the overall cross-sectional profile of the beacon portion of the system. The beacon element may be mounted with respect to the housing to be imaged in a direction transverse to the longitudinal axis of the system. The beacon element may include one or more LED's or other element imageable from a location separate from the target site.
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/273 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
A61B 1/313 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
27.
BEACON DEVICES, SYSTEMS, AND METHODS FOR MEDICAL PROCEDURES
A locator system having a flexible elongate delivery device, such as a flexible guidewire, advanced to a target site separately from the beacon element of the system. The beacon element may be configured to not extend beyond the perimeter of a housing on which the beacon element is mounted, thereby reducing the overall cross-sectional profile of the beacon portion of the system. The beacon element may be mounted with respect to the housing to be imaged in a direction transverse to the longitudinal axis of the system. The beacon element may include one or more LED's or other element imageable from a location separate from the target site.
The present disclosure pertains to a syringe comprising: a syringe barrel having an open proximal end that opens into an interior having a cylindrical wall and an angled distal surface terminating at an outlet; a plunger rod; and a plunger seal, a proximal end of the plunger seal configured to be attached to a distal end of the plunger rod, and a distal end of the plunger seal configured to be inserted into the interior of the syringe barrel through the open proximal end, the plunger seal forming a seal with the cylindrical wall of the interior of the syringe barrel, and the distal end of the plunger seal terminating at an angled distal surface, wherein the angled distal surface of the syringe barrel is more acute than the angled distal surface of the plunger seal. The present disclosure also pertains to kits containing such a syringe.
An elevator of a medical device may comprise: a plurality of segments joined together by at least one hinge, and a control element coupled to at least one segment of the plurality of segments. A first segment of the plurality of segments may be a discrete structure. Proximal or distal movement of the control element may be configured to move the at least one segment of the plurality of segments relative to another of the plurality of segments.
A medical device system may include a control unit comprising one or more processors that implement an algorithm to enhance images obtained by a medical device. The one or more processing boards perform the steps of: receiving a first image from the first viewing element; determining a current illumination value of the first image; determining a first difference between the current illumination value and a target high illumination value if the current illumination value is greater than the target high illumination value; determining a second difference between the current illumination value and a target low illumination value if the current illumination value is less than the target low illumination value; generating a new illumination value, using at least one of the first difference and the second difference; and converting the new illumination value to a first voltage value for application to one or more illuminators of the medical device.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
H04N 23/71 - Circuitry for evaluating the brightness variation
H04N 23/73 - Circuitry for compensating brightness variation in the scene by influencing the exposure time
H04N 23/74 - Circuitry for compensating brightness variation in the scene by influencing the scene brightness using illuminating means
H04N 23/76 - Circuitry for compensating brightness variation in the scene by influencing the image signals
31.
DEVICES, ASSEMBLIES, AND METHODS FOR DELIVERING AGENTS
A valve assembly for a medical device including a container including a first region and a second region, a first fluid inlet fluidly coupled to the first region, a second fluid inlet fluidly coupled to the second region, and a piston assembly disposed within the container. The container is configured to house an agent within the second region, the first fluid inlet is configured to deliver a first portion of pressurized fluid to the first region at a first pressure level, and the second fluid inlet is configured to deliver a second portion of pressurized fluid to the second region at a second pressure level that is less than the first pressure level. The piston assembly includes a valve configured to move from a first position to a second position in response to the piston assembly moving relative to the container.
A valve may have a fluid inlet and a fluid outlet. The valve may include a valve stem having a lumen extending from a first opening at a proximal portion of the valve stem to a second opening at a distal end of the valve stem. A plurality of seals may be positioned relative to the valve stem. The valve stem and seals may be configured so that a fluid entering the inlet is prevented from flowing to the outlet in a first position of the valve stem and relative to the inlet and the outlet. The valve stem and the seals may be configured so that a fluid entering the inlet flows to the outlet in a second position of the valve stem relative to the inlet and the outlet, the second position being more distal than the first position relative to the inlet and the outlet.
F16K 11/07 - Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves; Arrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with linearly sliding closure members with cylindrical slides
A61M 39/16 - Tube connectors or tube couplings having provision for disinfection or sterilisation
A tissue fastening device includes a body including a plurality of sidewalls defining a channel, an anvil having a proximal end and a distal end and pivotally coupled to the body and the anvil moves between an open position and a closed position, and a locking mechanism to lock the anvil in the closed position.
An implantable medical device having at least one compliant retention member configured not only to resist migration of the device with respect to its deployment site, but also to conform to anatomical forces applied thereto. The retention member may present a convex tissue-contacting surface to tissue at the deployment site and to which anatomical forces may be applied. The retention member may be compressible upon application of radially-inwardly directed anatomical forces thereto, but is sized, shaped, configured, and/or dimensioned to withstand forces tending to cause migration of the implantable medical device even when being compressed radially-inwardly. As such, the implantable medical device withstands forces applied thereto without building up internal stresses which may result in material fatigue.
An example medical device includes a container and tube set arranged and configured to couple to an endoscope, a first gas supply, and a second gas supply for use in an endoscopic procedure. The container and tube set includes a container having an interior volume configured to contain a fluid, a gas supply tube having a first end and a second end in fluid communication with the interior volume of the container, and a coupling mechanism having a first end and a second end, wherein the first end of the coupling mechanism is configured to engage with the second end of the gas supply tube and the second end of the coupling mechanism is configured to engage with both the first gas supply and the second gas supply interchangeably.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/12 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
36.
MANIFOLD DEVICES, ASSEMBLIES, AND METHODS FOR ENDOSCOPE SYSTEMS
Devices, systems, and methods for coupling tubing to a fluid reservoir to provide liquid to an endoscope system. A manifold for coupling to a fluid reservoir and a tubing assembly may include first portion interfacing with an interior of the fluid reservoir and a second portion configured to interface with tubing to be fluidly coupled to the interior of the reservoir. The first portion may include one or more openings to allow gas to pass into the fluid reservoir and liquid to pass out of the fluid reservoir. The second portion may include one or more ports for connecting to tubing that brings gas to the fluid reservoir and receives liquid from the fluid reservoir. The manifold may include a valve that selectively allows gas to pass into the fluid reservoir.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/12 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
Medical devices and methods of using medical devices are disclosed. An example tissue retraction device includes a first engagement member having a first end and a second end, a second engagement member having a first end and a second end, a first elastic member attached to the second end of the first engagement member, and a first alignment member having a first end, a second end and a lumen extending therethrough. Further, the tissue retraction device has a first length, the first alignment member has a second length, the first elastic member extends within the lumen of the first alignment member and the second length of the first alignment member is less than or equal to the first length of the tissue retraction device.
A method for evaluating a gastrointestinal tract may include receiving an electrical signal that includes data pertaining to motility in the gastrointestinal tract of a patient and analyzing one or more characteristics of the electrical signal relative to one or more respective thresholds indicative of an occurrence or an imminence of a condition of the gastrointestinal tract.
An elevator of a medical device may comprise: a plurality of segments joined together by at least one hinge, and a control element coupled to at least one segment of the plurality of segments. A first segment of the plurality of segments may be a discrete structure. Proximal or distal movement of the control element may be configured to move the at least one segment of the plurality of segments relative to another of the plurality of segments.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
An implantable medical device is adapted to be implanted at an implantation site within the vasculature and is capable of being implanted at the implantation site within the vasculature at more than one position relative to the implantation site. This may include a relative axial position and/or a relative rotational position. The implantable medical device includes an expandable frame that is adapted to expand from a collapsed configuration for delivery to an expanded configuration for deployment, and one or more radiopaque markers disposed relative to the expandable frame such that fluoroscopic imaging of the implantable medical device during deployment provides an indication of a position of the implantable medical device relative to the implantation site. The implantable medical device may be a replacement cardiac valve such as a replacement aortic valve, for example.
BOSTON SCIENTIFIC MEDICAL DEVICE LIMITED (Ireland)
BOSTON SCIENTIFIC SCIMED, INC. (USA)
Inventor
Sharma, Deepak Kumar
Gibson, Charles
Scutti, James
G., Sharath Kumar
Garcia, Juan Pablo Ortiz
Abstract
A guidewire assembly (100) may include a handle assembly (104) including: a handle body; a shaft (102) extending through the handle body; and an actuator (634). The guidewire assembly may further include a tube (105) extending distally from the handle assembly and including a proximal portion and a distal portion: and an interior body (401) extending from the handle assembly through the tube to the distal portion of the tube, wherein the interior body is coupled to the shaft. The shaft may be configured to move longitudinally through the handle body as the actuator is rotated to move interior body longitudinally through the tube.
An implantable medical device having at least one compliant retention member configured not only to resist migration of the device with respect to its deployment site, but also to conform to anatomical forces applied thereto. The retention member may present a convex tissue-contacting surface to tissue at the deployment site and to which anatomical forces may be applied. The retention member may be compressible upon application of radially-inwardly directed anatomical forces thereto, but is sized, shaped, configured, and/or dimensioned to withstand forces tending to cause migration of the implantable medical device even when being compressed radially-inwardly. As such, the implantable medical device withstands forces applied thereto without building up internal stresses which may result in material fatigue.
An implantable medical device is adapted to be implanted at an implantation site within the vasculature and is capable of being implanted at the implantation site within the vasculature at more than one position relative to the implantation site. This may include a relative axial position and/or a relative rotational position. The implantable medical device includes an expandable frame that is adapted to expand from a collapsed configuration for delivery to an expanded configuration for deployment, and one or more radiopaque markers disposed relative to the expandable frame such that fluoroscopic imaging of the implantable medical device during deployment provides an indication of a position of the implantable medical device relative to the implantation site. The implantable medical device may be a replacement cardiac valve such as a replacement aortic valve, for example.
Boston Scientific Medical Device Limited (Ireland)
Boston Scientific Scimed, Inc. (USA)
Inventor
Sharma, Deepak Kumar
Gibson, Charles
Scutti, James
G., Sharath Kumar
Garcia, Juan Pablo Ortiz
Abstract
A guidewire assembly may include a handle assembly including: a handle body; a shaft extending through the handle body; and an actuator. The guidewire assembly may further include a tube extending distally from the handle assembly and including a proximal portion and a distal portion; and an interior body extending from the handle assembly through the tube to the distal portion of the tube, wherein the interior body is coupled to the shaft. The shaft may be configured to move longitudinally through the handle body as the actuator is rotated to move interior body longitudinally through the tube.
A device includes an access cannula, a puncturing element, a handle. The access cannula includes a lumen extending therethrough. The access cannula is sized and shaped to extend through an endoscopic shaft to a target tissue within a living body. The puncturing element is sized and shaped to extend through the lumen of the access cannula and distally out a distal end of the access cannula. The handle includes a handle body and a mechanism for advancing the access cannula from a proximal position relative to the puncturing element, where a puncturing tip of the puncturing element is exposed distal to a distal end of the access cannula, to a distal position relative to the puncturing element, where the distal end of the access cannula covers the puncturing tip of the puncturing element.
A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/0205 - Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/349 - Detecting specific parameters of the electrocardiograph cycle
47.
SELF-EXPANDING TISSUE LUMEN STENTS WITH DRAINAGE ENHANCEMENT FEATURES
The disclosure provides a tissue lumen stent that has an elongated tubular configuration and a foreshortened configuration in which the upstream, the downstream, or both the upstream and downstream ends expand radially into flanged and/or flared structures while the region therebetween is generally cylindrical. The upstream flange structure has a larger maximum lateral dimension, axial width and/or axial radius than that of the downstream flange structure and may include an inclined portion having an axial length at least as long as a maximum diameter of the saddle region when the body is in the foreshortened configuration.
A61F 2/848 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
A61F 2/90 - Stents in a form characterised by wire-like elements; Stents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
48.
GRAPHICAL USER INTERFACE FOR INTRAVASCULAR ULTRASOUND CALCIUM DISPLAY
The present disclosure provides a graphical user interface (GUI) arranged to convey information related to the IVUS images and calcium detected in a vessel represented in the IVUS images. The GUIs can be generated to include a cross-section view and an interactive longitudinal view of the vessel include an indication of the location of the calcium relative to the longitudinal axis of the vessel.
A system for treating a vascular region includes an elongate catheter shaft having a distal end region, with an inner lumen formed in the elongate shaft and a fluid delivery lumen formed in the elongate shaft adjacent to the inner lumen. A treatment core is disposable within the inner lumen, and has one or more ultrasound transducers disposable adjacent to the distal end region of the elongate catheter shaft, the one or more ultrasound transducers including a proximal-most ultrasound transducer. The fluid delivery lumen is adapted such that fluid passing through the fluid delivery lumen exits the fluid delivery lumen at a position proximal to the proximal-most ultrasound transducer.
The present invention relates to a device for endoscopy or endosonography-guided transluminal interventions whereby two luminal structures in the body may be drawn toward each other and a fluid conduit formed in between. The device may have a hollow central member to which is coupled a distal retention member and in one embodiment a proximal retention member. The retention members may each be positioned inside one of the luminal structures and expanded from a first condition to an expanded second condition having an increased radius. The length of the central member may be shortened and its diameter expanded to approximate the two retention members and thereby the luminal structures.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
A61B 17/04 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for suturing wounds; Holders or packages for needles or suture materials
A61B 17/11 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for performing anastomosis; Buttons for anastomosis
According to an aspect, an inflatable penile prosthesis includes a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer the fluid between the fluid reservoir and the inflatable member. The pump assembly includes a pump bulb, a valve body, a valve disposed within the valve body, a first fluid port configured to be fluidly coupled to the fluid reservoir, and a second fluid port configured to be fluidly coupled to the inflatable member. The valve is configured to move between an inflation position and a deflation position. The valve includes a first member and second member, the first member being configured to move with respect to the second member.
A fluid management system includes a pump configured to pump fluid through the system at a fluid flow rate. The system includes a processor including a user interface, the user interface allowing a user to input a set of system operating parameters, the processor being configured to control the pump to maintain a target fluid flow rate based on the set of system operating parameters. The system further includes a scope device coupled to the pump to deliver fluid to a target surgical site, the scope device including an elongated shaft extending from a distal end thereof, the elongated shaft including at least one sensor, the sensor transmitting sensor data relating to target surgical site to the processor. The processor automatically signals to the pump to adjust the fluid flow rate based on the sensor data.
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
53.
GRAPHICAL USER INTERFACE FOR INTRAVASCULAR ULTRASOUND STENT DISPLAY
The present disclosure provides a graphical user interface (GUI) arranged to convey information related to the IVUS images and stents detected in a vessel represented in the IVUS images. The GUIs can be generated to include a cross-section view and an interactive longitudinal view of the vessel including an indication of the stent location relative to the longitudinal axis of the vessel.
The present disclosure provides to process intravascular ultrasound (IVUS) images to identify key frames such as the proximal key frame, a distal key frame, and a minimal key frame from the IVUS images based on the raw lumen area, vessel area, and plaque burden. Ones of the key frames can be re-identified based on manipulation of other ones of the key frames.
A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A61B 8/12 - Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof
55.
GRAPHICAL USER INTERFACE FOR INTRAVASCULAR ULTRASOUND AUTOMATED LESION ASSESSMENT SYSTEM
The present disclosure provides a graphical user interface (GUI) arranged to convey information related to the IVUS images and lesion assessment and provide for the user to manipulate the information. The GUIs can be generated to include a cross-section view without assessments post recording of IVUS images and to depict assessments after navigation through frames of the IVUS images.
A medical implant for occluding a left atrial appendage includes an expandable framework configured to shift between a collapsed configuration and an expanded configuration. The expandable framework includes a plurality of interconnected struts and a plurality of anchor members extending radially outward from the plurality of interconnected struts in the expanded configuration. Each anchor member of the plurality of anchor members includes a base portion fixedly attached to the plurality of interconnected struts and an anchor tip portion. The anchor tip portion includes a central penetrating element and at least one tissue support element extending outward from the central penetrating element. The at least one tissue support element is configured to be non-penetrating.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
57.
TREND LINES FOR SEQUENTIAL PHYSIOLOGICAL MEASUREMENTS OF VESSELS
The present disclosure provides to identify regions of a cardiac cycle based on pressure measured intravenously during a procedure and to derive a fractional flow reserve from the measured pressure during the identified regions. Further the disclosure provides to derive a trend line of the derived fractional flow reserve while the patient in undergoing a procedure, such as a pre-percutaneous coronary intervention.
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
58.
INTRAVASCULAR ULTRASOUND CO-REGISTRATION WITH ANGIOGRAPHIC IMAGES
The present disclosure provides to co-register an external image of a vessel to IVUS images captured within the vessel and provides graphical user interfaces to facilitate modification to the co-registration. Notably, the present disclosure provides for the co-registration even when the IVUS images are captured before the external image or before co-registration is initiated with the external image.
A system for treating a vascular region includes an elongate catheter shaft having a distal end region, with an inner lumen formed in the elongate shaft and a fluid delivery lumen formed in the elongate shaft adjacent to the inner lumen. A treatment core is disposable within the inner lumen, and has one or more ultrasound transducers disposable adjacent to the distal end region of the elongate catheter shaft, the one or more ultrasound transducers including a proximal-most ultrasound transducer. The fluid delivery lumen is adapted such that fluid passing through the fluid delivery lumen exits the fluid delivery lumen at a position proximal to the proximal-most ultrasound transducer.
A medical implant for occluding a left atrial appendage may include an expandable framework configured to shift between a collapsed configuration and an expanded configuration. The expandable framework may include a plurality of interconnected struts and a plurality of anchor members extending radially outward from the plurality of interconnected struts in the expanded configuration. Each anchor member of the plurality of anchor members may include a base portion fixedly attached to the plurality of interconnected struts and an anchor tip portion. The anchor tip portion may include a central penetrating element and at least one tissue support element extending outward from the central penetrating element. The at least one tissue support element may be configured to be non-penetrating.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
61.
GRAPHICAL USER INTERFACE FOR INTRAVASCULAR ULTRASOUND CALCIUM DISPLAY
The present disclosure provides a graphical user interface (GUI) arranged to convey information related to the IVUS images and calcium detected in a vessel represented in the IVUS images. The GUIs can be generated to include a cross-section view and an interactive longitudinal view of the vessel include an indication of the location of the calcium relative to the longitudinal axis of the vessel.
The present disclosure provides to identify regions of a cardiac cycle based on pressure measured intravenously during a procedure and to derive a fractional flow reserve from the measured pressure during the identified regions. Further the disclosure provides to derive a trend line of the derived fractional flow reserve while the patient in undergoing a procedure, such as a pre-percutaneous coronary intervention.
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
The present disclosure provides to co-register an external image of a vessel to IVUS images captured within the vessel and provides graphical user interfaces to facilitate modification to the co-registration. Notably, the present disclosure provides for the co-registration even when the IVUS images are captured before the external image or before co-registration is initiated with the external image.
The present disclosure relates generally to the field of medical devices for treating heart disease. In particular, the present disclosure relates to medical devices, systems, and methods for delivering artificial chordae tendineae in a patient. A system for delivering a chordae tendineae into a heart may include a delivery catheter. A clamp catheter may be configured to translate through the delivery catheter. A spreader may be disposed on the clamp catheter. A first clamp may be at least partially contained in the spreader in a closed configuration and may be attached to the chordae tendineae. An anchor catheter may be configured to translate through the delivery catheter and may have an anchor attached to the chordae tendineae. A sheath may be extended over the anchor catheter and anchor and may be configured to restrain an arm of the anchor.
A vapor delivery system and method is provided that includes a number of features. In one embodiment, a method comprises inserting a vapor delivery needle into tissue of a patient, activating a flow of vapor from a vapor generator through vapor delivery ports of the vapor delivery needle to cause condensed liquid to exit vapor delivery ports of the vapor delivery needle, generating vapor in the vapor generator, delivering a dose of vapor through the vapor delivery ports of the vapor delivery needle into the tissue, and after the dose of vapor is delivered, re-activating the flow of vapor from the vapor generator through the vapor delivery ports of the vapor delivery needle to prevent a vacuum from forming in the vapor delivery needle. Vapor therapy systems are also
The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices for facilitating the flow of fluids and materials in and/or between adjacent body lumens, for example, a stent which maintains an open flow passage between body lumens. In one example, a stent may comprise an elongate body configured to be expandable between a first constrained configuration and a second unconstrained configuration. In the unconstrained configuration, the body may have a first retention member, a second retention member, and a cylindrical saddle region defining a lumen extending along a longitudinal axis therebetween. The first retention member or the second retention member, or both, may comprise a double-walled flange with an axially inward wall and axially outward wall, a portion of the inward wall bending towards a vertical center plane of the saddle region along the longitudinal axis.
A61F 2/90 - Stents in a form characterised by wire-like elements; Stents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/852 - Two or more distinct overlapping stents
A vapor delivery needle and method is provided that is adapted for treating prostate cancer. The energy delivery probe can apply condensable vapor energy to tissue, such as a peripheral zone tissue in a human prostate. In one method, a needle is introduced into peripheral zone tissue of a human prostate, and vapor media is delivered through the needle to ablate peripheral zone tissue without ablating non-peripheral zone tissue. Systems for treating prostate cancer with vapor therapy are also provided.
A medical device may include an introducer sheath, having a distal and a proximal end and a lumen extending from the distal end to the proximal end. The introducer sheath may also include a tab formed at the distal end and extending distal to the lumen, and a frangible portion extending between the distal end and the proximal end.
Pressure sensing guidewires and methods for making and using pressure sensing guidewires are disclosed. An example pressure sensing guidewire may include a tubular member having a proximal region and a housing region. An optical pressure sensor may be disposed within the housing region. The optical pressure sensor may include a sensor body and a deflectable membrane coupled to the sensor body. The deflectable membrane may include a polymer. An optical fiber may be coupled to the sensor body and may extend proximally therefrom. A pressure equalization channel is formed in the optical fiber, the sensor body, or both.
An accessory device for an endoscope includes a cap attached to a shaft of the endoscope, the cap extending along a first axis, a first tip coupled to the cap and movable relative to the cap between a deployed configuration and a non-deployed configuration, and a first shaft defining a lumen and extending proximally from the first tip. In the deployed configuration, the first tip extends along a second axis that is offset from the first axis, and in the non-deployed configuration, the first tip extends along a third axis that is offset from the first axis.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
71.
GRAPHICAL USER INTERFACE FOR INTRAVASCULAR ULTRASOUND STENT DISPLAY
The present disclosure provides a graphical user interface (GUI) arranged to convey information related to the IVUS images and stents detected in a vessel represented in the IVUS images. The GUIs can be generated to include a cross-section view and an interactive longitudinal view of the vessel including an indication of the stent location relative to the longitudinal axis of the vessel.
The present disclosure provides to process intravascular ultrasound (IVUS) images to identify key frames such as the proximal key frame, a distal key frame, and a minimal key frame from the IVUS images based on the raw lumen area, vessel area, and plaque burden. Ones of the key frames can be re-identified based on manipulation of other ones of the key frames.
The present disclosure provides a graphical user interface (GUI) arranged to convey information related to the IVUS images and lesion assessment and provide for the user to manipulate the information. The GUIs can be generated to include a cross-section view without assessments post recording of IVUS images and to depict assessments after navigation through frames of the IVUS images.
G06F 3/0481 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
G06F 3/04845 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range for image manipulation, e.g. dragging, rotation, expansion or change of colour
G06T 11/20 - Drawing from basic elements, e.g. lines or circles
74.
SELF-EXPANDING TISSUE LUMEN STENTS WITH DRAINAGE ENHANCEMENT FEATURES
The disclosure provides a tissue lumen stent that has an elongated tubular configuration and a foreshortened configuration in which the upstream, the downstream, or both the upstream and downstream ends expand radially into flanged and/or flared structures while the region therebetween is generally cylindrical. The upstream flange structure has a larger maximum lateral dimension, axial width and/or axial radius than that of the downstream flange structure and may include an inclined portion having an axial length at least as long as a maximum diameter of the saddle region when the body is in the foreshortened configuration.
A clipping device includes a capsule including a longitudinal body and a cap mounted over a distal end thereof so that the cap is movable relative to the longitudinal body from a pre-deployed configuration to a deployed configuration in which the cap, is moved proximally relative to the longitudinal body to reduce a length of the capsule. A channel of the cap and a channel of the capsule are substantially aligned with respect to one another. At least proximal portions of a pair of clip arms are received within the channels of the cap and the longitudinal body so that the clip arms are movable relative to the capsule between an open configuration, in which distal ends of the clip arms are separated from one another, and a closed configuration, in which the distal ends of the clip arms are drawn toward one another.
A photoacoustic catheter adapted for placement within a blood vessel having a vessel wall includes an elongate shaft, a balloon and a photoacoustic transducer. The elongate shaft can extend from a proximal region to a distal region. The elongate shaft can include a light guide that is configured to be placed in optical communication with a light source. The balloon is coupled to the elongate shaft, and can be configured to expand from a collapsed configuration suitable for advancing the photoacoustic catheter through a patient's vasculature to a first expanded configuration suitable for anchoring the photoacoustic catheter in position relative to a treatment site. The photoacoustic transducer can be disposed on a surface of the balloon and in optical communication with the light guide. The photoacoustic transducer can include a light-absorbing material and a thermal expansion material.
A61B 17/22 - Surgical instruments, devices or methods, e.g. tourniquets for removing obstructions in blood vessels, not otherwise provided for
A61B 18/24 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor with a catheter
A handle of an endoscope may comprise a body portion that defines a first chamber having a first feature configured to support at least a first component of a steering assembly, and a second chamber having a second feature configured to support at least one fluidic component or electronic component.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
78.
CRIMP ATTACHMENT OF CLIP FOR RELOADABLE HEMOSTASIS DEVICE
A system includes a clip having a pair of clip arms, proximal ends of the clip arms received within a channel of a capsule to be moved between an open configuration and a closed configuration. A proximal end of the capsule including a plurality of connecting elements extending proximally therefrom. Each of the connecting elements including a hook along a proximal portion thereof. An applicator includes an elongated flexible member and a control member extending therethrough, the control member configured to be connected to the clip arms to move the clip assembly between the open and closed configurations, the elongated flexible member including a bushing including a first ramped portion and a necked portion extending proximally from the first ramped portion, a proximal end of the first ramped portion including a lip configured to engage the hook when the connecting elements are crimped thereover.
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
In some aspects, the present disclosure pertains to reactive multi-arm polymers having a cage-like silicon-oxygen core and a plurality of polyoxazoline-containing arms extending from the core, in which the polyoxazoline-containing arms comprise a first end that is covalently attached to the cage-like silicon-oxygen core and a second end comprising a moiety that comprises a reactive end group. In other aspects, the present disclosure pertains to systems that comprise such reactive multi-arm polymers and multifunctional compounds that comprise functional groups that are reactive with the reactive end groups of the reactive multi-arm polymers. Other aspects pertain to medical hydrogels formed by crosslinking such reactive multi-arm polymers with such multifunctional compounds and methods of treatment that comprise administering to a subject a mixture that comprises and such reactive multi-arm polymers with such multifunctional compounds.
An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of frame members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A vapor delivery needle is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply condensable vapor energy to tissue, such as a prostrate, to shrink, damage, or denature tissues of the prostate. Methods associated with use of the energy delivery probe are also covered.
A61B 18/08 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
83.
SYSTEMS, DEVICES, AND METHODS FOR THREE-DIMENSIONAL IMAGE REGISTRATION
A system includes a medical device and computer-readable media storing instructions that, when executed by a processor, cause operations to be performed, including: receiving a three-dimensional (3D) image of anatomy, processing the 3D image to extract a 3D model identifying anatomical structures of interest, receiving images captured by an imaging device of the medical device as the medical device is navigated through a body lumen to a target site, including a current image of the target site, receiving medical device spatial information from a position sensing system including a transmitter/receiver in or on the medical device, processing the images and spatial information to generate a 3D surface map of the body lumen, registering the 3D model to the patient using the map and spatial information, and generating and displaying a graphical user interface overlaying a representation of a position/ trajectory of the anatomical structures of interest on the current image.
A system for delivering a replacement heart valve implant may include a handle and a valve capsule, an inner shaft extending from the handle to the capsule, an outer sheath over the inner shaft and extending from the handle to the capsule, a positioning sheath over the outer sheath and extending from the handle, a guide tube within the handle, and a distal hub attached to the positioning sheath. The distal hub may be disposed within and movable relative to the guide tube via rotation of the positioning sheath. A method of manufacturing the system may include positioning proximal and distal hubs within the guide tube, setting a first predetermined distance between proximal and distal capsule portions, moving the positioning sheath relative to the outer sheath to set a second predetermined distance between the hubs, and securing the distal hub within the guide tube at the second predetermined distance.
In some aspects, the present disclosure pertains to systems for forming a hydrogel that comprise (a) an iodinated polyamino compound and (b) a reactive multi-arm polymer that comprises a plurality of hydrophilic polymer arms having unsaturated end groups that are reactive with amino groups of the iodinated polyamino compound. Other aspects of the present disclosure pertain to medical hydrogels that are formed by crosslinking the iodinated polyamino compound and the reactive multi-arm polymer of such systems. Further aspects of the present disclosure pertain to medical procedures that can be performed using such systems.
In various aspects, the present disclosure pertains to systems for forming hydrogels that comprise an iodinated polyamino compound and a reactive multi-arm polymer that comprises a plurality of hydrophilic polymer arms having reactive end groups that are reactive with amino groups of the iodinated polyamino compound. Other aspects of the present disclosure pertain to medical hydrogels that are formed by crosslinking the iodinated polyamino compound and the reactive multi-arm polymer of such systems. Further aspects of the present disclosure pertain to medical procedures that can be performed using such systems. Still other aspects of the present disclosure pertain to methods of making iodinated polyamino compounds.
C07C 273/18 - Preparation of urea or its derivatives, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
87.
LEAK PREVENTION DEVICES, SYSTEMS, AND METHODS FOR ENDOSCOPE SYSTEMS
Devices, systems, and methods for mitigating leakage from connectors and tubing of an endoscope system when the connectors and or tubing are disconnected from fluid ports of the endoscope system. A tubing assembly for connecting a fluid line to an endoscope and a fluid source may include an elongate tube having a lumen, a connector coupled to an end of the elongate tube and having a port in fluid communication with the lumen, and a fluid control component configured to selective adjust fluid flow through the lumen and the port. The fluid control component may be located in one or more of a cover for the fluid source, the tubing, the connector, and/or other components in fluid communication with the lumen. The fluid control component may be a valve. The valve may be manually actuated from a closed position to an opened position.
A61B 1/12 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
F16K 7/06 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with tubular diaphragm constrictable by external radial force by means of a screw-spindle, cam, or other mechanical means
88.
SYSTEMS AND METHODS FOR TREATING THE BLADDER WITH CONDENSABLE VAPOR
A vapor delivery system and method is provided that is adapted for ablating bladder tissue to treat overactive bladder (OAB). The vapor delivery system includes an anchor tip configured anchor the system in the bladder while condensable vapor is delivered to target tissue. In one method, the vapor delivery system is advanced transurethrally into the patient to access the target tissue of the bladder, which can include a surface sensor of the bladder responsible for creating an urge incontinence sensation. The vapor delivery system includes a vapor source that provides a high quality vapor for delivery to tissue.
An implant includes a pair of anchors and a pair of anchor housing assemblies, wherein an anchor housing assembly includes an anchoring component configured to translate the anchor proximally-distally through the anchor housing assembly and a cinch component configured to control a space between the pair of anchor housing assemblies.
A medical device including an elongate member having a proximal end, a distal end, and a lumen extending therebetween. The medical device may further include an end-effector disposed at the distal end of the elongate member. The end-effector may include a plurality of arms pivotally connected to one another, wherein each arm includes a tissue-contacting surface, a first portion of the tissue-contacting surface including a plurality of ridges configured to grasp tissue. Further, the tissue-contacting surface may include a channel oriented substantially parallel to a longitudinal axis of the medical device.
An endoprosthesis for preventing collapse of a vein may include an expandable framework configured to shift between a radially collapsed configuration and a radially expanded configuration, and a plurality of anchoring legs extending axially away from a first end of the expandable framework. The plurality of anchoring legs may be configured to shift between a delivery configuration and a deployed configuration. In the deployed configuration, the plurality of anchoring legs may be configured to extend radially outward of the expandable framework in the radially expanded configuration. A system for preventing collapse of a vein may include a delivery catheter having a lumen, an endoprosthesis disposable within a distal portion of the lumen in a radially collapsed configuration, and at least one filament coupled to the plurality of anchor legs of the endoprosthesis and extending within the lumen of the delivery catheter.
An implantable medical device system having at least two implantable medical devices coupled together with a connector while implanted at a common anatomical region. The connector allows the implantable medical devices to anchor one another in place at respective deployment sites. Moreover, the connector may function as a safety device by causing one implantable medical device to migrate upon migration of another implantable medical device. For instance, if migration of an implantable medical device causes a structural change in the common anatomical region, such change may be generally reversible upon migration of the other implantable medical device as a result of the implantable medical devices being coupled via the connector.
A61B 17/04 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for suturing wounds; Holders or packages for needles or suture materials
A61B 17/11 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for performing anastomosis; Buttons for anastomosis
A61F 5/00 - Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices
93.
LEAK PREVENTION DEVICES, SYSTEMS, AND METHODS FOR ENDOSCOPE SYSTEMS
Devices, systems, and methods for mitigating leakage from connectors and tubing of an endoscope system when the connectors and or tubing are disconnected from fluid ports of the endoscope system. A tubing assembly for connecting a fluid line to an endoscope and a fluid source may include an elongate tube having a lumen, a connector coupled to an end of the elongate tube and having a port in fluid communication with the lumen, and a fluid control component configured to selective adjust fluid flow through the lumen and the port. The fluid control component may be located in one or more of a cover for the fluid source, the tubing, the connector, and/or other components in fluid communication with the lumen. The fluid control component may be a valve. The valve may be manually actuated from a closed position to an opened position.
B05B 7/24 - Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas with means, e.g. a container, for supplying liquid or other fluent material to a discharge device
B05B 9/04 - Spraying apparatus for discharge of liquid or other fluent material without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pump
B05B 12/00 - Arrangements for controlling delivery; Arrangements for controlling the spray area
B05B 7/12 - Spray pistols; Apparatus for discharge designed to control volume of flow, e.g. with adjustable passages
F16K 7/06 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with tubular diaphragm constrictable by external radial force by means of a screw-spindle, cam, or other mechanical means
F16K 3/26 - Gate valves or sliding valves, i.e. cut-off apparatus with closing members having a sliding movement along the seat for opening and closing with sealing faces shaped as surfaces of solids of revolution with cylindrical valve members with fluid passages in the valve member
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of frame members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
Methods and systems for coupling gas and water supply tubes to a container. An illustrative container and tube set may comprise a container configured to contain a fluid, the container having a bottom portion and a top portion, a water supply tube including a first end, a second end, and a first lumen, a gas supply tube including a first end, a second end, and a second lumen, and a weight coupled to the first end of the water supply tube and a first end of the gas supply tube. The first lumen may be in selective fluid communication with the bottom portion of the container and the second end of the water supply tube positioned external to the container. The second lumen may be in operative fluid communication with the container and the second end of the gas supply tube is positioned external to the container.
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
97.
SYSTEMS, DEVICES, AND METHODS FOR THREE-DIMENSIONAL IMAGE REGISTRATION
A system includes a medical device and computer-readable media storing instructions that, when executed by a processor, cause operations to be performed, including: receiving a three-dimensional (3D) image of anatomy, processing the 3D image to extract a 3D model identifying anatomical structures of interest, receiving images captured by an imaging device of the medical device as the medical device is navigated through a body lumen to a target site, including a current image of the target site, receiving medical device spatial information from a position sensing system including a transmitter/receiver in or on the medical device, processing the images and spatial information to generate a 3D surface map of the body lumen, registering the 3D model to the patient using the map and spatial information, and generating and displaying a graphical user interface overlaying a representation of a position/trajectory of the anatomical structures of interest on the current image.
G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
A61B 5/06 - Devices, other than using radiation, for detecting or locating foreign bodies
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A61B 34/20 - Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A left atrial appendage closure implant may include a support frame including a first bend extending from a proximal collar to a second bend, a first segment extending from the second bend to a third bend, a second segment extending from the third bend to a fourth bend, and a third segment extending from the fourth bend to a distal collar, wherein the support frame is actuatable from a first constrained position to a second flowering position to a third mid-deployment position to a fourth unconstrained position. An implant may include a self-expanding support frame having a circumference and a central longitudinal axis, a membrane disposed over at least a portion of the support frame, and a plurality of anchors arranged into a first row and a second row such that the first row and the second row form a staggered pattern about the circumference of the support frame.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
The present disclosure relates generally to the field of medical devices and medical device accessories. In particular, the present disclosure relates to a tool or accessory for cleaning a medical device. For example, the tool or accessory may clean a fluid delivery lumen of an endoscopic submucosal dissection (ESD) knife. The tool or accessory may include a housing with a first portion of an elongate member secured within a first portion of the housing and a second portion of the elongate member extending into a chamber of the housing.
A cannulation device is adapted to gain access to the patient's common bile duct (14). In some instances, the cannulation device includes a first guidewire lumen (34) extending through an elongate shaft and terminating at a first oblique guidewire port (36), and a second guidewire lumen (38) extending through the elongate shaft and terminating at a second oblique guidewire port (40). In some instances, the cannulation device includes an inflatable balloon (72,80,92) that is inflatable from a collapsed configuration to an expanded configuration in which the inflatable balloon is adapted to occlude the patient's pancreatic duct (16). In some instances, the cannulation device includes an expandable element (118,140) that is expandable from a collapsed configuration in which the expandable element is disposed within the guidewire lumen and an extended configuration in which a portion of the expandable element extends distally from a guidewire port.
