The United States of America, as represented by the Secretary, Department of Health and Human Services

United States of America

 
Total IP 2,726
Total IP Rank # 429
IP Activity Score 3.8/5.0    1,576
IP Activity Rank # 449

Patents

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Last Patent 2024 - M971 chimeric antigen receptors
First Patent 1982 - Method for reducing toxic effect...

Latest Inventions, Goods, Services

2023 Invention M971 chimeric antigen receptors. The invention provides a chimeric antigen receptor (CAR) compri...
Invention Powered gait assistance systems. Disclosed are powered gait assistance systems that include a co...
Invention Engineered sars-cov-2 antibodies with increased neutralization breadth. Disclosed are monoclonal ...
Invention Single domain antibodies targeting hpv e6/e7 oncogenic peptide/mhc complexes. HHH) antibody libra...
Invention Vaccines against coronaviruses. The present disclosure relates to the field of vaccines and bindi...
Invention Synergistic interactions for improved cancer treatment. This disclosure provides compositions and...
Invention Systems and methods for electrocardiographic radial depth navigation of intracardiac devices. Var...
Invention Surgical tool and method for soft ocular tissue transplantation. Disclosed are devices and metho...
Invention Dual-germline antibody engager hiv-1 envelope chimeric immunogens. The invention provides an HIV-...
Invention Halophthalimide compounds and methods of use against tbi, inflammatory disorder, autoimmune disor...
Invention Multi-cyclic irak1 and irak4 inhibiting compounds and uses thereof. The present disclosure provid...
Invention Monoclonal antibodies that bind to the underside of influenza viral neuraminidase. Monoclonal ant...
Invention Selective opioid receptor agonists and antagonists. Compounds having opioid characteristics are p...
Invention Method of immmunofocusing an immune response. The present disclosure relates to vaccines, therape...
Invention Kinase inhibitors. Disclosed is a class of kinase inhibitors. Related pharmaceutical compositions...
Invention Compositions and methods for treatment of virus-induced airway fibrosis. Methods of treating or i...
Invention Impeding platinum-based chemotherapeutic induced ototoxicity using a colony stimulating factor 1 ...
Invention Very-long-chain polyunsaturated fatty acids (vlcpufa) for improving retina/cognitive functions an...
Invention Cell-barcode recorder devices and methods. In aspects, the disclosure provides devices and method...
Invention Methods and compositions for improving wound healing. The present disclosure relates to compositi...
Invention Anti-sars-cov-2 antigen binding polypeptides, polypeptide complexes and methods of use thereof. D...
Invention Cd25-specific antibodies and uses thereof. Monoclonal antibodies that specifically bind CD25, as ...
Invention Augmenting mitochondria in immune cells for improved cancer immunotherapy. The present invention ...
Invention Immunogens and methods for inducing an immune response. This disclosure generally relates to meth...
Invention Multi-cyclic irak and flt3 inhibiting compounds and uses thereof. Some embodiments of the disclos...
Invention Viral strain serology assays. The invention relates to methods and kits for determining a SARS-Co...
Invention Echocardiographic estimation of right atrial pressure using a lightweight and open-world artifici...
Invention Computationally engineered monocolonal antibodies and antigen binding fragments specific for sars...
Invention Compositions, systems, and methods for delivery of therapeutics. The present disclosure provides ...
Invention Compounds for inhibiting gram-positive bacteria. Compounds and methods for their use in inhibitin...
Invention Compositions and methods for pharmacologic treatment of stroke and myocardial ischemia reperfusio...
Invention Predicting patient response to cancer therapy via histopathology images. A method of training an ...
Invention Engineered cell-penetrating antiviral compound. Compounds for inhibiting the replication of intra...
Invention Live-attenuated sars-cov-2 vaccine. Engineered SARS-CoV-2 variants having a combination of attenu...
Invention Compositions and methods for detecting lymphatic filariasis. ,, are provided, including the antig...
Invention E. coli. E. colilac E. coliE. coliE. coli.
Invention Replicating rna vaccine for crimean-congo hemorrhagic fever virus. Described herein are construct...
Invention Pim-targeted protacs with pim-binding moieties sgi-1776, azd-1208 or pim-447, and a e3 ubiquitin ...
Invention Vaccine for human t-lymphotropic virus-1. Provided herein is a nucleic acid-based vaccine for hum...
Invention Systems and method for synchronous circumferential intramyocardial resynchronization and pacing. ...
Invention Modified factor xa polypeptides and methods of use. Modified Factor Xa polypeptides having functi...
2021 Invention Novel var2csa immunogens and methods of use thereof. The disclosure provides immunogen polypepti...
Invention Tyrosyl-lock peptides. Disclosed is a class of knotted cyclic peptides. Related pharmaceutical c...
Invention Enhanced antigen reactivity of immune cells expressing a mutant non-signaling cd3 zeta chain. Di...
Invention Rna sensors and uses thereof. The invention generally concerns a novel class of cyclopentane mod...
Invention Plk1 polo box domain inhibitors and method of treating cancer. Provided is a method of treating ...
Invention Novel adeno-associated viral (aav) vectors to treat hereditary methylmalonic acidemia (mma) cause...