Abrégé

The present invention provides a use of deslorelin acetate in preparation of a drug for adjusting a sexual cycle of an animal. The animal is a rat, and the drug is an injection, preferably administered by subcutaneous injection. By using the drug of the present invention, there is no need to sample each animal every day, which allows for significant time cost savings and labor cost savings, and the sexual cycle of the rat can be determined without depending on staff's experience in identifying the sexual cycle of the animal, so as to achieve the effect of accurate breeding, and for a sexual cycle disorder of the adult female rat, the cycle of the animal is synchronized and the breeding efficiency is improved by using the drug, and the conception rate of the female rat is as high as 100%.

Classes IPC  ?

• A61K 38/09 - Hormone libérant l'hormone lutéinisante [LHRH]; Peptides apparentés
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuels; Contraceptifs

Abrégé

An intelligent magnetic resonance holographic imaging method and system. The system comprises: a data acquisition device (10), an image reconstruction device (20) and an image display device (30); the data acquisition device (10) is used for acquiring under-sampled magnetic resonance data in real time by means of under-sampled scanning (S110), and sending same to the image reconstruction device (20); the image reconstruction device (20) is used for inputting the under-sampled magnetic resonance data into a deep learning model, so as to output a high-dimensional stereoscopic reconstructed image (S130), the deep learning model being obtained by means of self-supervised training by using under-sampled magnetic resonance data of a sample as input and corresponding fully-sampled magnetic resonance data as output (S120); and the image display device (30) is used for performing stereoscopic rendering on the stereoscopic reconstructed image, and performing stereoscopic display by means of holographic projection (S140). The system can achieve rapid magnetic resonance imaging and real-time stereoscopic magnetic resonance image display, thereby better assisting doctors in performing surgical intervention treatment.

Classes IPC  ?

• G06T 5/00 - Amélioration ou restauration d'image
• G06N 3/08 - Méthodes d'apprentissage
• G01R 33/561 - Amélioration ou correction de l'image, p.ex. par des techniques de soustraction ou d'établissement de moyenne par réduction du temps de balayage, c.à d. systèmes d'acquisition rapide, p.ex. utilisant des séquences d'impulsions écho-planar

Abrégé

A sampling device for high-throughput preparation of a microorganism sample for mass spectrometry. The sampling device comprises: a mounting base; and a plurality of sampling needles, which are arranged on the mounting base at intervals in a preset distribution. Each sampling needle comprises: an elongated main body, which is approximately perpendicular to the mounting base; a connecting end, which is formed at one end of the main body and connected to the mounting base; and a sampling end, which is formed at the other end of the main body. By means of the sampling device of the present application, multiple microorganism samples can be obtained by means of one sampling operation, thereby simplifying the sampling operation and improving the sampling efficiency.

Classes IPC  ?

• C12M 1/26 - Inoculateur ou échantillonneur

Abrégé

The present invention relates to the technical field of chip circuits, and in particular to a dedicated chip ADC circuit for a retinal prosthesis. The circuit comprises: a sampling switch module, a capacitor array module, a dynamic comparator, a digital control logic module, and a digital correction module; the capacitor array module comprises a P-terminal capacitor array and an N-terminal capacitor array, the P-terminal capacitor array comprises a plurality of first capacitors connected in parallel, and each first capacitor is connected to a first control switch; the N-terminal capacitor array comprises a plurality of second capacitors connected in parallel, and each second capacitor is connected to a second control switch; a same-direction terminal of the dynamic comparator is connected to a tail end capacitor of the P-terminal capacitor array, and a reverse-direction terminal of the dynamic comparator is connected to a tail end capacitor of the N-terminal capacitor array; the digital control logic module is connected to an output terminal of the dynamic comparator; and the digital correction module is connected to an output terminal of the digital control logic module. The ADC circuit provided in the present invention is used for converting sensor analog signals into digital signals, thereby achieving low power consumption and high resolution.

Classes IPC  ?

• H03M 1/00 - Conversion analogique/numérique; Conversion numérique/analogique
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
• H03M 1/46 - Valeur analogique comparée à des valeurs de référence uniquement séquentiellement, p.ex. du type à approximations successives avec convertisseur numérique/analogique pour fournir des valeurs de référence au convertisseur
• H03M 1/06 - Compensation ou prévention continue de l'influence indésirable de paramètres physiques
• A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
• A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil

Abrégé

The present invention relates to the technical field of rapid pathological testing. Disclosed is a dark-field reflection ultraviolet optical microscopic imaging method, comprising the following steps: S10, acquiring a tissue sample; S20, placing the tissue sample on an objective stage, and ultraviolet light generated by an ultraviolet light source being obliquely incident onto the tissue sample; and collecting ultraviolet reflected light from the tissue sample by using an ultraviolet optical system, and obtaining an ultraviolet dark-field reflection image by means of a bright signal which is generated by means of diffuse reflection light on a shallow-surface layer of the tissue sample, and a dark signal which is generated by means of a cell nucleus absorbing incident ultraviolet light. On the basis of dark-field illumination of ultraviolet light, when the interference of specular reflection light and scattered light is eliminated, an image contrast is provided by using the dark signal which is generated by means of a cell nucleus absorbing ultraviolet incident light, and the bright signal which is generated by means of diffuse reflection light on the shallow-surface layer of the tissue sample. The method requires no fluorescent staining, and a sample requires no special slicing treatment, such that a pathological tissue imaging result can be rapidly and accurately provided at a high signal-to-background ratio, and a rapid and accurate reference basis is provided for intraoperative incisal-margin evaluation.

Classes IPC  ?

• G02B 21/16 - Microscopes adaptés pour éclairage ultraviolet
• G01N 21/47 - Dispersion, c. à d. réflexion diffuse
• G01N 21/64 - Fluorescence; Phosphorescence

Abrégé

The present invention provides a bile acid metabolizing bacterium for preventing and treating an inflammatory bowel disease and use thereof. The present invention provides a bacterium which comprises any one, two or three of the following strains: Clostridium sp. with the collection number of GDMCC No: 62707, Eubacterium limosum with the collection number of GDMCC No: 62708, and Bacteroides ovatus with the collection number of GDMCC No: 62709. The bacterium of the present invention can convert primary bile acids into secondary bile acids, ameliorating the inflammation symptoms of DSS-induced ulcerative colitis in mice.

Classes IPC  ?

• C12N 1/20 - Bactéries; Leurs milieux de culture
• A61K 35/74 - Bactéries
• A61P 1/04 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des ulcères, des gastrites ou des œsophagites par reflux, p.ex. antiacides, antisécrétoires, protecteurs de la muqueuse
• C12R 1/01 - Bactéries ou actinomycètes
• C12R 1/145 - Clostridium

Abrégé

A system and method for registration of preoperative and intraoperative liver point cloud data, and a terminal and a storage medium. The method comprises: extracting local hybrid features of preoperative point cloud data and local hybrid features of intraoperative point cloud data (S1); fusing the local hybrid features to obtain global features of a preoperative point cloud and global features of an intraoperative point cloud (S2); fusing the local hybrid features and global features of the preoperative point cloud and the global features of the intraoperative point cloud to obtain fused features of the preoperative point cloud, and obtaining fused features of the intraoperative point cloud in the same way (S3); fusing the fused features of the preoperative point cloud and the fused features of the intraoperative point cloud to obtain respective overlap region masks and decoded features (S4); obtaining spatial transformation matrices of the preoperative point cloud and the intraoperative point cloud (S5); and applying the spatial transformation matrices to the preoperative point cloud data to obtain a registration result of the preoperative point cloud data and the intraoperative point cloud data (S6). The method and system can facilitate the accurate localization of a liver tumor, thereby shortening the surgical operation time and improving the precision and safety of a surgical operation.

Classes IPC  ?

• G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images utilisant des procédés basés sur les caractéristiques
• G06T 17/20 - Description filaire, p.ex. polygonalisation ou tessellation

Abrégé

Provided in the present application are a cellular mechanical property measurement and sorting system and method, and a terminal and a storage medium. The method comprises: cells to be sorted being arranged in a straight line after passing through a standing wave acoustic field generated by a first interdigital transducer; the cells, which are arranged in a straight line, flowing through a focused acoustic field generated by a second interdigital transducer, and the focused acoustic field generating a radiation force on the cells, such that the cells are deformed; a cellular elastic modulus calculation unit performing calculation according to information of the radiation force and deformation, so as to obtain elastic moduli of the cells; a cell locating unit determining the positions of the cells, and selectively driving, with designed delay time, interdigital transducers in a cell sorting unit according to the moving speeds of the cells and the distances between the cells and the sorting unit, and the cell sorting unit triggering, according to the elastic moduli, a corresponding interdigital transducer to generate a planar acoustic field, so as to sort the cells. By means of the sorting system and method, and the terminal and the storage medium, cellular elasticity measurement and sorting are realized by means of ultrasound in a non-contact manner, thereby reducing the damage to cells.

Classes IPC  ?

• G01N 15/10 - Recherche de particules individuelles

Abrégé

A numerical control machine tool, comprising: a base (10); a movement-axis assembly (20), which is arranged on the base (10); a rotary-axis assembly (30), which is arranged on the base (10), wherein part of the structure of the rotary-axis assembly (30) moves under the action of part of the structure of the movement-axis assembly (20), thereby performing turn-milling compound machining on a component; and a clamping assembly (40), which is arranged on the base (10) and is used for clamping and fixing the component. The clamping assembly (40) comprises a first fixing member (401), a mounting member (402), a driving member (403) and a turn-over member (404). The present application uses the technical solution of a seven-axis structure having three rotary axes and four movement axes, thereby completing complete machining and double-sided machining of small complex components within one machining cycle.

Classes IPC  ?

• B23P 23/02 - Machines-outils effectuant différentes opérations d'usinage
• B23B 19/02 - Broches de travail; Caractéristiques s'y rapportant, p.ex. agencements des supports
• B23Q 3/06 - Moyens de fixation de la pièce
• B23Q 5/10 - Entraînement des principaux organes de travail des arbres rotatifs, p.ex. des broches de travail entraînés principalement par des moyens électriques
• B23Q 5/28 - Transmissions électriques

Abrégé

An enzyme sequence generation method and apparatus based on multiple sequence alignment, and a storage medium. The enzyme sequence generation method comprises: from a sequence database, screening for a plurality of similar amino acid sequences similar to a complete amino acid sequence of a target enzyme (S10); performing multiple sequence alignment processing on the complete amino acid sequence and the plurality of the similar amino acid sequences to obtain a plurality of aligned amino acid sequences, wherein each aligned amino acid sequence has the same length (S20); training a pre-constructed generative adversarial network model by using the plurality of aligned amino acid sequences as training samples to obtain an amino acid sequence generation model (S30); and using the amino acid sequence generation model to generate a plurality of extended amino acid sequences of the target enzyme (S40). By screening for similar natural amino acid sequences and performing multiple sequence alignment processing, a model can fully learn and retain key site information in the amino acid sequences, so that a higher proportion of new amino acid sequences generated by using the model have enzyme activity.

Classes IPC  ?

• G16B 30/10 - Alignement de séquence; Recherche d’homologie
• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion

Abrégé

The present invention relates to a sirtuin mutant, a method for high-throughput screening of a sirtuin mutant, and use. The screening method for a sirtuin mutant comprises the following steps: constructing a sirtuin mutant library using an error-prone PCR technology; lysing each mutant in the sirtuin mutant library, carrying out solid-liquid separation, and collecting a lysate supernatant; and determining the deacylation activity of sirtuin in the lysate supernatant using an AMC fluorescence method, and obtaining a sirtuin mutant strain with the required deacylation activity. By using the screening method for a sirtuin mutant, a mutant of the deacylation enzyme sirtuin can be simply, conveniently, and repeatedly selected using a high throughput method.

Classes IPC  ?

• C12N 15/01 - Préparation de mutants sans introduction de matériel génétique étranger; Procédés de criblage à cet effet
• C12N 15/00 - Techniques de mutation ou génie génétique; ADN ou ARN concernant le génie génétique, vecteurs, p.ex. plasmides, ou leur isolement, leur préparation ou leur purification; Utilisation d'hôtes pour ceux-ci
• C12N 9/08 - Oxydoréductases (1.), p.ex. luciférase agissant sur le peroxyde d'hydrogène comme accepteur (1.11)

Abrégé

23222. The glass/ceramic composite material has low softening temperature and good sintering promotion performance, ceramic having excellent microwave dielectric performance can be separated out at a high temperature, the compatibility with a silver electrode is better, and the ceramic can be used for adjusting dielectric, mechanical, and thermal properties of the composite material.

Classes IPC  ?

• C03C 14/00 - Compositions de verre contenant un constituant non vitreux, p.ex. compositions contenant des fibres, filaments, trichites, paillettes ou similaires, dispersés dans une matrice de verre
• C04B 35/057 - Produits céramiques mis en forme, caractérisés par leur composition; Compositions céramiques; Traitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxyde de magnésium, d'oxyde de calcium ou de mélanges d'oxydes dérivés de la dolomite à base d'oxyde de calcium
• C03C 12/00 - Poudre de verre; Compositions pour billes en verre
• C03B 19/06 - Autres méthodes de façonnage du verre par frittage

Abrégé

The present invention relates to a joint assistance and energy recovery apparatus, comprising a human-machine fixation device, a power generation unit, a control system, and an energy storage unit. The power generation unit comprises a power generator and a transmission apparatus; two binding mechanisms transmit a joint movement to the transmission apparatus; the transmission apparatus increases the speed of the joint movement and transmits the joint movement to the power generator; the power generation unit is configured to recover mechanical energy of a human joint during movement, and provide impedance resistance for the joint in a specific movement process, thereby reducing the walking burden of a human knee joint; and the energy storage unit is configured to store electric energy recovered by the power generator, and the control system is configured to control the power generation power and the power generation current of the power generation unit, or to adjust the impedance torque of the power generation unit. The present invention can be used for recovering the biological mechanical energy of human joints in the walking process, and can also be used for providing an impedance torque for a wearer in the process of going downhill or downstairs, thereby reducing the walking burden of the wearer.

Classes IPC  ?

• B25J 9/00 - Manipulateurs à commande programmée

Abrégé

The present application discloses a method for testing neural pathway activation, an apparatus, a device, and a storage medium. The method comprises: acquiring pre-stimulation field potential data and post-stimulation field potential data corresponding to a neural pathway to be tested of an experimental subject; on the basis of the pre-stimulation field potential data and the post-stimulation field potential data, determining connection strength change data of the neural pathway to be tested; on the basis of video data to be tested of the experiment subject, determining behavior change data of the experiment subject; and on the basis of the connection strength change data and the behavior change data, determining the activation state of said neural pathway.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G06V 20/40 - RECONNAISSANCE OU COMPRÉHENSION D’IMAGES OU DE VIDÉOS Éléments spécifiques à la scène dans le contenu vidéo

Abrégé

The present application belongs to the technical field of electromagnetic shielding materials. Provided are an electromagnetic shielding composite material with a temperature response characteristic, and a preparation method therefor and the application thereof. The composite material is an electromagnetic shielding composite material with a temperature response characteristic, uses vanadium dioxide as a functional material, and is prepared by means of compounding the functional material and a matrix material. Further provided are a preparation method for and the application of the electromagnetic shielding composite material with a temperature response characteristic. In the composite material, vanadium dioxide is changed from an insulation state to a metal state when the temperature of the vanadium dioxide exceeds a phase-change temperature, so that the electromagnetic shielding performance of the composite material has a temperature response characteristic, and the composite material intrinsically produces a tunable electromagnetic response to heat without undergoing structural deformation; moreover, the composite material also has a recyclable feature, such that the reliability of the material is greatly improved, and the composite material has wide application prospects, and is of great significance for application in a device as an intelligent temperature-controlled electromagnetic shielding switch.

Classes IPC  ?

• C01G 31/02 - Oxydes
• C01G 31/00 - Composés du vanadium
• H01C 1/06 - Dispositions d'écrans électrostatiques ou électromagnétiques

Abrégé

Disclosed in the present application are an acoustic-wave non-invasive brain-computer interface and a control method. The brain-computer interface comprises: an ultrasound cerebral blood flow imaging module, an analysis and control module, and an execution device, wherein the ultrasound cerebral blood flow imaging module is configured to acquire, in real time, initial cerebral blood flow imaging information of a target object, and send the initial cerebral blood flow imaging information to the analysis and control module; the analysis and control module is connected to the ultrasound cerebral blood flow imaging module, and is configured to acquire the initial cerebral blood flow imaging information, determine a control signal according to the initial cerebral blood flow imaging information, and send the control signal to the execution device; the execution device comprises at least one of an action device or an ultrasound stimulation device; and the execution device is connected to the analysis and control module, and is configured to receive the control signal and execute, according to the control signal, a response action.

Classes IPC  ?

• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
• A61B 8/06 - Mesure du débit sanguin
• A61N 7/00 - Thérapie par ultrasons

Abrégé

Provided are an MXene modification method and a use thereof. MXene modification is to modify an MXene by using amino acid, and the method comprises the following steps: mixing MXene nanosheets with amino acid molecules in a solution to complete modification. Starting from the root cause of MXene oxidation reaction, the adsorption of the amino acid molecules on the surface of the MXene is implemented by utilizing the hydrogen bond and coordination bond action between the amino acid molecules and the MXene, and attack reaction sites of water and oxygen in the oxidation process are occupied, thereby preventing the oxidation and the degradation of the MXene in the water, improving the oxidation resistance of the MXene, and further improving the stability of structure and properties. According to the modification method, inherent attributes of the MXene such as morphology are not changed, the oxidation resistance of an MXene material can be greatly improved, a prepared thin film keeps original good mechanical properties, and the electromagnetic shielding performance is basically unchanged or slightly reduced.

Classes IPC  ?

• C01B 32/921 - Carbure de titane
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• H05K 9/00 - Blindage d'appareils ou de composants contre les champs électriques ou magnétiques

Abrégé

Disclosed in the present invention are a gecko-claw-imitating composite thermal interface material and a preparation method therefor. The method comprises the following steps: (1) preparing a polymer-based thermal interface material prepolymer on a template having a micron-scale array structure on the surface, and demolding same to obtain a polymer-based thermal interface material prepolymer having a micron-scale array structure on the surface; and (2) implanting carbon nanotubes into the micron-scale array structure of the polymer-based thermal interface material prepolymer obtained in step (1) by means of an electrostatic flocking method, and curing same to obtain a gecko-claw-imitating composite thermal interface material. In the present invention, by means of treating the surface structure of a thermal interface material, a micro-nano two-level gecko-claw-imitating structure is formed, such that an interface contact area is effectively increased, an interface adsorption force is enhanced, and interfacial thermal contact resistance is reduced.

Classes IPC  ?

• C08K 3/04 - Carbone
• H01L 23/373 - Refroidissement facilité par l'emploi de matériaux particuliers pour le dispositif
• F28F 21/00 - Structure des appareils échangeurs de chaleur caractérisée par l'emploi de matériaux spécifiés

Abrégé

An energy spectrum image processing method, an apparatus, a computer device, and a storage medium. The method comprises: determining an initial material image sequence corresponding to measured energy spectrum data (S101); inputting into a trained energy spectrum data model the material data corresponding to the initial material image sequence so as to obtain estimated energy spectrum data (S102); if the difference between the estimated energy spectrum data and the measured energy spectrum data is within a set error range, using the initial material image sequence as a desired material image sequence (S103); and otherwise, adjusting the material data according to the difference, and using a material image sequence corresponding to the adjusted material data as a desired material image sequence (S104). The problem that existing energy spectrum image processing methods have low quantitative substance decomposition precision is solved.

Classes IPC  ?

• G06T 11/00 - Génération d'images bidimensionnelles [2D]

Abrégé

Disclosed in the present application are a vehicle control method and apparatus, a terminal device, and a computer-readable storage medium. The vehicle control method comprises: during the process of a vehicle pulling into a target area, recording a pulling-in path of the vehicle pulling into the target area; during the process of the vehicle pulling out of the target area, acquiring a pulling-out position of the vehicle in real time; determining a steering wheel angle according to the position deviation between the pulling-out position and the pulling-in path; and controlling, according to the steering wheel angel, the vehicle to pull out of the target area along the pulling-in path. By means of the method, a vehicle can be automatically controlled to return along an original path, thereby improving the degree of intelligence of autonomous driving.

Classes IPC  ?

• B60W 30/06 - Manœuvre automatique de stationnement

Abrégé

Provided is a motor neuromuscular vascular coupling function detection system, which comprises: a muscle oxygen measurement module (11), covering a part to be detected and configured to acquire a muscle oxygen signal of said part under motor stimulation, wherein the muscle of said part is associated with a target motor nerve; and a processor (12), configured to acquire state time information. The muscle oxygen measurement module (11) acquires the muscle oxygen signal of said part under motor stimulation, a time response characteristic parameter of the muscle oxygen signal is determined on the basis of the state time information, and a motor neuromuscular vascular coupling analysis result of said part is determined on the basis of the time response characteristic parameter.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
• A61B 5/389 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG]

Abrégé

A neurovascular coupling analysis method and apparatus for peripheral nerves, and an electronic device. The method comprises: receiving a motion muscle oxygen signal of a target detection muscle in a motion state acquired by a blood oxygen signal acquisition device (S110); according to state time information of the motion state, determining a muscle oxygen signal time response characteristic parameter of the motion muscle oxygen signal (S120); and based on the muscle oxygen signal time response characteristic parameter, determining a neurovascular coupling analysis result of a target peripheral nerve (S130).

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/389 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG]
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale

Abrégé

A robotic system for respiratory diagnosis and treatment and a control method therefor. The present invention relates to the technical field of medical machinery. The system comprises a master end control apparatus for operating and controlling sending of a control instruction, a slave end control apparatus for receiving the control instruction of the master end control apparatus and performing an operation action, and a navigation apparatus for tracking and guiding the slave end control apparatus. The slave end control apparatus comprises a slave end robot, and a slave end embedded controller installed inside the slave end robot. The slave end robot is provided with a robotic arm (3), a propulsion support plate (14) connected to the robotic arm (3), a biopsy instrument introduction mechanism (13) connected to the propulsion support plate (14) and used for delivering a biopsy instrument, a bronchoscope rotation transmission mechanism (11) for controlling a bronchoscope, and a bending control mechanism (12) for controlling the angle of the flexible tail end of the bronchoscope. The master end control apparatus sends out a control instruction, and the slave end control apparatus receives the control instruction of the master end control apparatus and performs an operation action; meanwhile, the navigation apparatus tracks and guides the slave end control apparatus to deliver a biopsy instrument and clamp focus tissue.

Classes IPC  ?

• A61B 34/37 - Robots maitres-esclaves
• A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
• A61B 10/02 - Instruments pour prélever des échantillons cellulaires ou pour la biopsie
• A61B 10/04 - Instruments endoscopiques

Abrégé

Disclosed are a non-invasive subcranial imaging monitoring method and a kit, wherein the non-invasive subcranial imaging monitoring method comprises: penetrating a liquid chelating agent and a transparent skull filling liquid into a non-invasive intact skull (9); fixing a base on the skull (9), a miniaturized microscope (2) being carried on the base; and in combination with the miniaturized microscope (2), imaging fluorescence signals under the skull (9) in real time to monitor the activity correlation of signals under the skull (9) in real time. The method achieves long-term stable, clear, and synchronous real-time monitoring of signals under the skull (9).

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre

Abrégé

Disclosed in the present application are a model training method based on a market price prediction model, a price prediction method based on a market price prediction model, and a terminal device and a computer storage medium. The model training method comprises: acquiring a data set; calculating a historical price technical index on the basis of stock market data of each time period; calculating a historical social media market sentiment index on the basis of social media data of each time period; associating and merging the historical price technical index and the historical social media market sentiment index in the same time period, and inputting same as features into a market price prediction model to be trained; and training the market price prediction model by using a prediction output of the market price prediction model to be trained, so as to obtain a final market price prediction model. By means of the model training method in the present application, the time granularity of prediction is reduced by means of the characteristic of continuous updating of social media, so as to obtain a capability of almost real-time prediction; and in view of a market technical index, a better prediction effect is achieved.

Classes IPC  ?

• G06Q 30/02 - Marketing; Estimation ou détermination des prix; Collecte de fonds

Abrégé

Provided are a microvascular position detection method, apparatus and system, and a storage medium. The method comprises: in response to detecting a trigger instruction, controlling, on the basis of a first preset wavelength, a light source (411) in a signal acquisition array (410) to irradiate a measured subject, and obtaining first reflected light signals acquired, respectively, by at least two photodetectors (412) in the signal acquisition array (410) (S110), wherein the light source (411) in the signal acquisition array (410) is in a linear arrangement with each photodetector (412); for each of the photodetectors (412), when the first reflected light signal acquired by the photodetector (412) is a periodic signal, taking a component distance between the photodetector (412) and the light source (411) as a target component distance (S120); and on the basis of the target component distance and a detection depth corresponding to the photodetector (412), determining the vascular position of microvessels (S130). The problem that the traditional vascular detection method cannot detect the microvascular position is solved, and accurate microvascular position information is provided for medical operation, thereby being capable of reducing the occurrence rate of iatrogenic vascular injury.

Classes IPC  ?

• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
• G01B 11/02 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur
• G01B 11/00 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques

Abrégé

The present application relates to the technical field of electrolyte salt preparation processes, and in particular to a method for preparing hexafluorophosphate. The method for preparing hexafluorophosphate of the present application comprises the following steps: dissolving ammonium hexafluorophosphate and a material source containing a metal element in a solvent to obtain a mixed solution, wherein the material source containing the metal element is selected from at least one of a metal elementary substance, metal carbonate, metal nitrate, metal sulfate and metal hydroxide corresponding to the metal element, and the metal element is selected from one of lithium, sodium, potassium, calcium, magnesium and barium; performing stirring reaction on the mixed solution to obtain a reaction liquid containing hexafluorophosphate; and performing solvent removal treatment on the reaction liquid containing hexafluorophosphate to obtain hexafluorophosphate. The method for preparing hexafluorophosphate provided by the present application has the characteristics of greenness, low cost and high efficiency, and has good application prospects in the technical field of electrolyte salt preparation processes.

Classes IPC  ?

• C01B 25/455 - Phosphates halogénés

Abrégé

Disclosed in the present application are a structural-acoustic coupling processing method and apparatus based on model order reduction, and a terminal device, which are applicable to the technical field of computer structural acoustic assistance. The method comprises: in response to an excitation signal of a preset frequency band, acquiring the response frequency of an engineering structure system; acquiring a structural-acoustic coupling system equation of the engineering structure system according to the response frequency; and performing analysis processing on the response frequency on the basis of an order reduction model corresponding to the structural-acoustic coupling system equation, so as to obtain a target structural displacement and the sound pressure of a target sound field of the engineering structure system. In the structural-acoustic coupling processing method based on model order reduction, parameters of an engineering structure system can be adjusted, such that a target structural displacement and the sound pressure of a target sound field of the engineering structure system are regulated and controlled in a timely manner, thereby controlling the vibration of the structure in the engineering structure system and controlling the noise of the sound field. Therefore, the structural-acoustic coupling processing method has relatively high usability and practicability.

Classes IPC  ?

• G06F 30/23 - Optimisation, vérification ou simulation de l’objet conçu utilisant les méthodes des éléments finis [MEF] ou les méthodes à différences finies [MDF]
• G06F 119/10 - Analyse du bruit ou optimisation du bruit

Abrégé

Disclosed in the present application are a high temporal-spatial resolution energy spectrum CT imaging method and apparatus based on a multi-layer flat panel detector. The method comprises: determining a temporal-spatial resolution of a target imaged image according to an imaging requirement of a target imaging object; determining pixel binning parameters of a multi-layer flat panel detector on the basis of the temporal-spatial resolution, and setting a pixel binning unit of each layer of flat panel detector according to the pixel binning parameters so that pixel binning units of different layers of detectors in the multi-layer flat panel detector are arranged in a staggered manner; and executing a scanning operation on the basis of a scanning protocol, and acquiring binning unit signals, which are read out by the multi-layer flat panel detector on the basis of the pixel binning units.

Classes IPC  ?

• A61B 6/03 - Tomographes assistés par ordinateur

Abrégé

Provided is a mesenchymal stem cell osteogenic differentiation induction solution, comprising a culture medium and piperazine. On the basis of a traditional induction solution, piperazine is used to replace dexamethasone, achieving the effects of osteogenic differentiation and osteogenic mineralization of mesenchymal stem cells. Piperazine is not considered to be a corticoid, has a relatively small influence on other cell metabolism, and industrial preparation of piperazine is simple and inexpensive. In addition, on the basis of piperazine having the effect of promoting osteogenic differentiation and mineralization, piperazine can be developed as a potential medication for treating bone defects, osteoporosis and other bone-related diseases; moreover, piperazine can be used as a small-molecule substance and loaded onto a carrier to be used for achieving the functions of osteogenic differentiation and mineralization.

Classes IPC  ?

• C12N 5/077 - Cellules mésenchymateuses, p.ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
• A61K 31/495 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec deux azote comme seuls hétéro-atomes d'un cycle, p.ex. pipérazine
• A61F 2/28 - Os

Abrégé

A sound pressure evaluation method based on a model order reduction boundary element method, comprising: acquiring a model to be evaluated and a frequency domain of interest corresponding thereto (101); performing order reduction on the model to be evaluated, so as to generate a low-dimensional reduced-order model corresponding to the model to be evaluated (102); and performing frequency sweep computation on the low-dimensional reduced-order model on the basis of the frequency domain of interest, so as to generate a sound pressure evaluation result in the frequency domain of interest that is corresponding to the model to be evaluated (103). Sound pressure evaluation efficiency is improved. Further provided are a sound pressure evaluation apparatus based on a model order reduction boundary element method, a terminal device and a computer-readable storage medium.

Classes IPC  ?

• G01H 17/00 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores non prévue dans les autres groupes de la présente sous-classe
• G06F 30/20 - Optimisation, vérification ou simulation de l’objet conçu

Abrégé

Provided are an anti-A-FABP monoclonal antibody 2C6, a preparation method therefor and a use thereof. The monoclonal antibody is high in sensitivity and good in specificity, and can be used for methods such as Western blot, ELISA, and Flow Cytometry for testing A-FABP.

Classes IPC  ?

• C07K 16/18 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
• C12N 15/13 - Immunoglobulines
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present application provides an anti-A-FABP monoclonal antibody, a preparation method therefor, and a use thereof. The monoclonal antibody has the advantages of high sensitivity, good specificity, and the like, and can be widely applied to different methods, such as Western blot, ELISA, and flow Cytometry, to detect A-FABP.

Classes IPC  ?

• C07K 16/18 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
• C12N 15/13 - Immunoglobulines
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present application is applicable to the technical field of image processing. Provided are a 3D virtual object animation generation method and apparatus, a terminal device, and a medium. The animation generation method comprises: successively performing three-dimensional reconstruction on a reference object in each video frame of a target video to obtain three-dimensional reconstruction information of the reference object in each video frame; according to the three-dimensional reconstruction information of the reference objects in all the video frames and a preset object model, generating a first animation sequence corresponding to the reference object, the preset object model comprising a preset skeleton; on the basis of the preset skeleton, performing skeleton retargeting on the target skeleton of the target virtual object to obtain a retargeted skeleton, the structure of the target skeleton being the same as or similar to the structure of the preset skeleton; and, on the basis of the first animation sequence, performing animation retargeting on the retargeted skeleton to obtain a second animation sequence corresponding to the target virtual object, thereby improving animation generation efficiency of the target virtual object.

Classes IPC  ?

• G06T 13/40 - Animation tridimensionnelle [3D] de personnages, p.ex. d’êtres humains, d’animaux ou d’êtres virtuels

Abrégé

Boevoevolutionary algorithm (EVO), the problem of the amount of calculation being excessively great caused by BO locating global optimum by means of exhaustively searching the whole design space is solved by EVO; and the defects of greedy and under-exploration of the EVO are neutralized by the exploratory property of BO, such that efficient iteration between a machine learning model and a robot experiment is achieved, and high-value new protein variants are economically acquired. By using the method of the present invention, there is the potential to realize efficient and extensible calculation and exploration, and an efficient biological sequence engineering modification solution is provided.

Classes IPC  ?

• C12N 15/00 - Techniques de mutation ou génie génétique; ADN ou ARN concernant le génie génétique, vecteurs, p.ex. plasmides, ou leur isolement, leur préparation ou leur purification; Utilisation d'hôtes pour ceux-ci
• C40B 10/00 - CHIMIE COMBINATOIRE; BIBLIOTHÈQUES, p.ex. CHIMIOTHÈQUES Évolution moléculaire dirigée des macromolécules, p.ex. ARN, ADN ou protéines

Abrégé

A CT pancreatic tumor automatic segmentation method and system, a terminal, and a storage medium. The method comprises: acquiring a three-dimensional CT image to be segmented (S100); preprocessing the three-dimensional CT image (S101); inputting into a trained UMRFormer network model the preprocessed three-dimensional CT image, and the UMRFormer network model generating feature maps of different scales, encoding long-term dependency semantic information of the feature maps, and outputting a tumor segmentation result of the three-dimensional CT image (S102). By embedding a Transformer-like module having fused advantages of involving feature local and global dependencies, the novel UMRFormer network model with deep fusion of feature global long-range correlations and spatial local information learns feature information of more small pancreatic tumor targets and feature information of global long-term dependencies between the tumors and peripheral tissue, thereby improving the overall segmentation precision of a network.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• G06V 10/26 - Segmentation de formes dans le champ d’image; Découpage ou fusion d’éléments d’image visant à établir la région de motif, p.ex. techniques de regroupement; Détection d’occlusion
• G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p.ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersections; Analyse de connectivité, p.ex. de composantes connectées
• G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux

Abrégé

The present application discloses a facial expression recognition method and apparatus, and a device and a readable storage medium. The method comprises: determining a region image where each facial action unit on a human face in a target facial image is located; determining the action intensity of each facial action unit according to the target facial image; determining a facial expression enhanced image according to intensity information of each facial action unit and the target facial image; and inputting the region image, which corresponds to each facial action unit, and the facial expression enhanced image into a preset neural network model for processing, so as to obtain an expression recognition result of the target facial image. The method can effectively improve the expression recognition accuracy of a facial image.

Classes IPC  ?

• G06V 40/16 - Visages humains, p.ex. parties du visage, croquis ou expressions

Abrégé

Provided are a wearable spine health monitoring device and system based on multi-channel myoelectricity. The monitoring device comprises an elastic substrate and an upper garment. The elastic substrate is fixed on a rear garment piece (1) of the upper garment, and symmetrically distributed multi-channel myoelectricity acquisition electrode points (2) are arranged on the elastic substrate. During use, the elastic substrate is attached to the back and fixed by means of wearing the upper garment. The monitoring device can achieve rapid arrangement and attachment of large-area back multi-channel myoelectricity, is easy to wear and take off and wear for a long time, can monitor myoelectricity information on the left side and the right side of the back in daily dynamic motion or rehabilitation treatment for a long time, can achieve real-time evaluation of spine activity, and solve the problems of lack of accurate evaluation of spinal neuromuscular physiological information and lack of long-term and real-time monitoring tools for spine health in the existing spine health screening.

Classes IPC  ?

• A61B 5/256 - Moyens pour maintenir le contact de l’électrode avec le corps Électrodes portables, p.ex. avec des sangles ou des bandes
• A61B 5/296 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électromyographie [EMG]
• A61B 5/389 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG]

Abrégé

Provided are a blind guiding method and apparatus, and a readable storage medium, being suitable for the technical field of blind guiding. The method comprises: acquiring a first image sequence by means of a camera, the first image sequence comprising a first image at a first moment (201); according to the first image sequence, acquiring an environment map at the first moment and pose information of the camera in the environment map at the first moment (202); identifying a first object in the first image, and acquiring semantic information of the first object and a mask of the first object (203); projecting the mask of the first object into the environment map at the first moment, and acquiring three-dimensional position information of the first object (204); according to the pose information of the camera in the environment map at the first moment and the three-dimensional position information of the first object, acquiring relative pose information between the camera and the first object (205); and broadcasting the relative pose information and the semantic information of the first object (206). The method and apparatus are beneficial for helping visually impaired people to perceive the surrounding environment more accurately, and the reliability of the blind guiding method is improved.

Classes IPC  ?

• G01C 21/00 - Navigation; Instruments de navigation non prévus dans les groupes
• A61H 3/06 - Aides pour la marche destinées aux aveugles
• G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
• G06V 20/00 - RECONNAISSANCE OU COMPRÉHENSION D’IMAGES OU DE VIDÉOS Éléments spécifiques à la scène

Abrégé

Provided is an epoxy molding compound, comprising an epoxy resin pretreated by a stress absorbent, which is a mixture obtained by melt blending of a stress absorbent and an epoxy resin, the stress absorbent being a styrene-butadiene copolymer or a derivative thereof; a phenolic resin pretreated by an inorganic nanofiller, which is a mixture obtained by melt blending of a phenolic resin and an inorganic nanofiller; an inorganic microfiller; and a curing accelerator. The epoxy molding compound comprises 5-15 parts by weight of the epoxy resin, 0.1-5 parts by weight of the stress absorbent, 0.5-10 parts by weight of the inorganic nanofiller, 5-8 parts by weight of the phenolic resin, 65-90 parts by weight of the inorganic nanofiller and the inorganic microfiller, and 0.1-1.5 parts by weight of the curing accelerator. The present application further provides a method for preparing the epoxy molding compound, a semiconductor packaging structure, and an electronic apparatus. The pretreatment of the inorganic nanofiller and the stress absorbent can further reduce the modulus of the epoxy molding compound.

Classes IPC  ?

• C08L 63/00 - Compositions contenant des résines époxy; Compositions contenant des dérivés des résines époxy
• C08L 61/00 - Compositions contenant des polymères de condensation d'aldéhydes ou de cétones; Compositions contenant des dérivés de tels polymères
• C08K 3/36 - Silice

Abrégé

Provided is a gene editing method for the genome of bacteria capable of producing bacterial cellulose. The method comprises the following steps: S1) determining a target gene or site to be modified in bacteria capable of producing cellulose membranes, and determining a first homologous arm sequence according to the target gene or site to be modified; S2) preparing a donor plasmid, wherein the donor plasmid comprises a replication initiation site, a screening gene and a second homologous arm sequence for allelic exchange with a genome; and S3) transferring the prepared donor plasmid into the bacteria capable of producing cellulose membranes, performing culturing, and performing screening by means of a screening method corresponding to the screening gene to obtain gene-edited recombinant bacteria of the bacteria capable of producing cellulose membranes, wherein the sequence of the donor plasmid, which is linearized, is inserted into a target gene or site to be modified in the genome of the recombinant bacteria. By means of the present invention, rapid and simple genetic modification is performed on the genome of bacteria capable of producing cellulose membranes by using a single recombination method.

Classes IPC  ?

• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p.ex. Lactobacillus, Micromonospora
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteurs; Vecteurs; Utilisation d'hôtes pour ceux-ci; Régulation de l'expression
• C12N 1/20 - Bactéries; Leurs milieux de culture
• C12R 1/02 - Acetobacter

Abrégé

Provided are a transgenic animal model, a method for constructing same, and use thereof. An Axinlflox/flox transgenic mouse is used to mate with an Agcl-CreER transgenic mouse to produce an Axin1+AgclER condition knockout mouse. Then by means of tamoxifen induction, the Axin1 expression in the Axin1+AgclER condition knockout mouse is down-regulated, and a disease combined model with the pathological characteristics of "growth plate chondrocyte hypertrophy, heterotopic ossification and articular cartilage degeneration of knee joints" is successfully established. The model is similar to clinically related pathological features, and can be used for systematically studying the pathogenesis of growth plate chondrocyte hypertrophy, heterotopic ossification and osteoarthritis and further screening for drugs for treating related diseases.

Classes IPC  ?

• C12N 15/90 - Introduction stable d'ADN étranger dans le chromosome
• A61K 49/00 - Préparations pour examen in vivo
• A01K 67/027 - Nouvelles races de vertébrés

Abrégé

A wobble doll-like capsule robot, relating to the field of medical instruments. The wobble doll-like capsule robot comprises: a housing (1), the housing (1) being configured as a cylinder having one end being an opening; protruding structures (7) are arranged at two ends of lateral sides in a length direction of the housing (1), the protruding structures (7) being used for keeping the balance of the robot; the two ends in the length direction of the housing (1) are configured to be elliptical; the opening end of the housing (1) is connected to a cylindrical housing cover (2) matched with the housing (1); the housing (1) and the housing cover (2) form a sealed wobble doll-like structure, and the wobble doll-like structure is used for keeping the robot positioned or oriented in the same direction. A Halbach magnetic field module (3) is eccentrically arranged in the housing (1), and an integrated circuit control board (4) is arranged at a position lower than the center of mass of the housing (1), thereby offsetting the center of gravity of the capsule robot and enabling continuous directional positioning by means of the described structural properties in combination with the magnetic control of the Halbach magnetic field module (3). Thus the efficiency of the robot is improved, and the posture adjustment is flexible, and the robot is suitable for different working environments.

Classes IPC  ?

• A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
• A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
• A61B 1/273 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments pour l'appareil digestif supérieur, p.ex. œsophagoscopes, gastroscopes

Abrégé

Disclosed are a light-emitting plant and a preparation method therefor. The preparation method mainly comprises the following steps: firstly, preparing a long afterglow material; grinding the long afterglow material to obtain a ground long afterglow material, and combining the ground long afterglow material with a carrier to prepare an intermediate product; and finally placing the intermediate product on the plant leaves; or directly placing the ground long afterglow material on the plant leaves. The light-emitting plant does not need to consume the energy of the plant itself during the light-emitting process, which can greatly improve the efficiency of synthesizing organic matter under photosynthesis. Moreover, the light-emitting plant can emit light of different colors and shapes, which is ornamental and can also replace the light sources used in life, thereby achieving the purpose of saving electric energy.

Classes IPC  ?

• A01G 7/06 - Traitement des arbres ou des plantes en cours de croissance, p.ex. pour prévenir la décomposition du bois, pour teinter les fleurs ou le bois, pour prolonger la vie des plantes
• A01G 22/60 - Fleurs; Plantes d’ornement

Abrégé

A polymer microsphere preparation apparatus (300) and method. The polymer microsphere preparation apparatus (300) comprises a microsphere generation assembly (200) and a collection container (10), wherein the microsphere generation assembly (200) comprises a continuous phase runner (1), a discrete phase runner (2), a primary runner (3), a first guide pipe (5), a second guide pipe (6), a third guide pipe (7), and working electrodes (4); the continuous phase runner (1) and the discrete phase runner (2) intersect and converge into the primary runner (3); the working electrodes (4) are arranged on two sides of the primary runner (3), and are close to a starting end of the primary runner (3); the first guide pipe (5) is inserted into the continuous phase runner (1), the second guide pipe (6) is inserted into the discrete phase runner (2), and the third guide pipe (7) is inserted into the tail end of the primary runner (3); the second guide pipe (6) is of a conductive structure; and the collection container (10) is connected to the third guide pipe (7) by means of a guide pipe. By means of the preparation method, a microfluidic chip is coupled with electrospray technology, such that a prepared microsphere has a large controllable size range, good dispersity and monodispersity, and uniformity, and the preparation method can be suitable for the preparation of various fluorescent matrix fluorescent microspheres.

Classes IPC  ?

• B01J 13/14 - Polymérisation, réticulation
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes

Abrégé

The present invention provides engineered bacteria capable of producing bacterial cellulose for producing a targeted therapeutic active ingredient and a preparation method for the engineered bacteria. Host bacteria of the engineered bacteria are bacteria capable of secreting bacterial cellulose, the host bacteria express the active ingredient by inserting exogenous fragments into the genome or introducing exogenous plasmids; the fragments inserted into the genome or the exogenous plasmids have a gene encoding the targeted therapeutic active ingredient; and at the same time, the engineered bacteria maintain the ability of original host bacteria of secreting bacterial cellulose. The present invention provides the engineered bacteria capable of producing a bacterial cellulose membrane, which not only can produce the cellulose membrane, but also can serve as a reaction vessel of the targeted therapeutic active ingredient, thereby producing the targeted therapeutic active ingredient in mass quantities. In addition, according to the present invention, by means of a pre-screening method, it is ensured that the engineered bacteria do not affect the production of the bacterial cellulose membrane while being capable of expressing the active ingredient.

Classes IPC  ?

• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p.ex. Lactobacillus, Micromonospora
• C12N 1/21 - Bactéries; Leurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12R 1/01 - Bactéries ou actinomycètes
• C12R 1/02 - Acetobacter
• A01N 63/20 - Bactéries; Substances produites par des bactéries ou obtenues à partir de celles-ci
• C07K 14/195 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries

Abrégé

The present application discloses an imaging method, an imaging apparatus, an electronic device and a computer storage medium. The imaging method comprises: for each preset frequency in a preset frequency range, transmitting a radio frequency pulse of the preset frequency to a target area, the radio frequency pulse being used for exciting water and fat in the target area, such that the water and the fat in the target area are excited to a saturated state; after emitting the radio frequency pulse is finished, collecting a saturation signal corresponding to the preset frequency; comparing the saturation signals corresponding to all the preset frequencies with a pre-collected initial signal to determine a mixed signal of water and fat in the preset frequency range; calculating a first signal of the water; and on the basis of the mixed signal and the first signal, determining a second signal, and on the basis of the spectral distribution of the second signal, generating a fat peak map of the target area, the second signal being a signal of the fat. According to the method, imaging can be directly carried out on the basis of the spectral distribution of the fat signal, and the spatial resolution of an image can be improved.

Classes IPC  ?

• A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique

Abrégé

The present application is suitable for the technical field of image processing, and provides an image processing method and device, comprising: obtaining a target image frame, a plurality of memory image frames and a guidance image frame, wherein the plurality of memory image frames comprise a mask of a lesion, and a change difference between the target image frame and the guidance image frame is within a preset range; performing local similarity calculation on the target image frame and each memory image frame according to a time dimension of the plurality of memory image frames to obtain a time feature map; performing spatial similarity calculation on the target image frame and the guidance image frame to obtain a spatial feature map; and determining a predicted mask of a lesion in the target image frame according to the time feature map and the spatial feature map. Therefore, by means of decoupling and parallel processing of time dimension and space dimension, the calculation complexity and time costs are reduced, calculation resources are saved, and the detection speed and the detection precision for a lesion area are improved, thereby satisfying real-time and low-delay detection requirements.

Classes IPC  ?

• G06T 7/11 - Découpage basé sur les zones
• G06T 7/00 - Analyse d'image
• G06T 5/50 - Amélioration ou restauration d'image en utilisant plusieurs images, p.ex. moyenne, soustraction
• G06V 10/74 - Appariement de motifs d’image ou de vidéo; Mesures de proximité dans les espaces de caractéristiques
• G06V 10/80 - Fusion, c. à d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion
• G06N 3/08 - Méthodes d'apprentissage

Abrégé

The present invention relates to the field of robot devices. Disclosed is an indoor construction robot. The indoor construction robot comprises: a movable base, an execution unit, a sensing unit, and a control unit; wherein the execution unit comprises a robotic arm and an operation execution portion connected to one end of the robotic arm; the execution unit, the sensing unit, and the control unit are all carried on the movable base; the sensing unit comprises a laser radar provided on the movable base and a displacement sensor provided on the operation execution portion; and the movable base, the execution unit, and the sensing unit are all connected to the control unit. According to the present invention, by means of cooperation of the high-precision positioned movable base and the displacement sensor on the operation execution portion, the flatness of a wall surface operation plane of the robot is effectively ensured, and the working efficiency of the decoration robot is improved.

Classes IPC  ?

• B25J 11/00 - Manipulateurs non prévus ailleurs

Abrégé

Disclosed in the present application are a neural network training method, a human activity recognition method, and a device and a storage medium. The neural network training method comprises: acquiring a training data set, and preprocessing training data in the training data set, so as to obtain a plurality of pieces of training graph data, wherein each piece of training graph data is training graph data of one time slice in the training data; inputting the training graph data into a graph neural network for training, wherein the graph neural network comprises a plurality of graph convolutional layers which are connected in sequence; and on the basis of a training result, acquiring a final weight matrix of the graph neural network, and thereby completing neural network training, wherein the weight matrix of the graph neural network is composed of the final weights of the plurality of graph convolutional layers. By means of the method, in the present application, data preprocessing is performed on a training data set, thereby obtaining training graph data meeting an input of a graph neural network, and thus improving the training efficiency and the training accuracy of a neural network.

Classes IPC  ?

• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion

Abrégé

Provided in the present application are a bone-targeted extracellular vesicle, and a preparation method therefor and the use thereof. The bone-targeted extracellular vesicle comprises an extracellular vesicle in which the outer surface is modified with a bone-targeted molecule, and an osteogenesis-promoting drug loaded in the extracellular vesicle. By means of the bone-targeted extracellular vesicle disclosed in the present application, accurate delivery of a target organ is realized by means of bone tissue targeting, and an osteogenesis promoting effect is improved by means of loading the osteogenesis-promoting drug. When the bone-targeted extracellular vesicle is prepared, the bone targeting modification reaction on the extracellular vesicle is mild and convenient, such that the structure of the extracellular vesicle is not damaged, and the performance of the extracellular vesicle is not affected. Moreover, the polypeptide bone-targeted molecule used in the present application has low toxicity and mild side effects, and a good bone targeting effect.

Classes IPC  ?

• A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c. à d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
• A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
• A61K 47/46 - Ingrédients de constitution indéterminée ou leurs produits de réaction, p.ex. peau, os, lait, fibre de coton, coquille d’oeuf, fiel de boeuf ou extraits de plante
• A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p.ex. rachitisme, maladie de Paget
• C12N 5/0775 - Cellules souches mésenchymateuses; Cellules souches dérivées du tissu adipeux

Abrégé

Disclosed in the present application are an image partitioning method, apparatus and device, and a readable storage medium. The method comprises: acquiring a biological tissue slice dyed image to be partitioned; determining image blocks to be processed in the biological tissue slice dyed image; performing feature extraction on each said image block, so as to obtain a tissue morphological feature vector of each said image block, wherein each element in the tissue morphological feature vector corresponds to the response intensity of a tissue morphological feature in said image block; on the basis of the tissue morphological feature vectors of said image blocks, clustering said image blocks, so as to obtain a clustering result of said image blocks; and on the basis of the clustering result of said image blocks, partitioning the biological tissue slice dyed image. By using the scheme, a biological tissue slice dyed image can be partitioned on the basis of clustering, and there is no need to perform supervised training to obtain a biological tissue slice dyed image partition model.

Classes IPC  ?

• G06T 7/00 - Analyse d'image

Abrégé

A calibration method for a low-frequency performance test of an all-fiber detector, comprising: attaching parallel plate capacitor structures (1) at two ends of a detection probe (2) and applying an alternating-current voltage signal, wherein the detection probe (2) is driven to vibrate up and down so that optical fibers on the detection probe (2) are deformed in an alternating-current form; acquiring a phase change amount of the optical fibers by means of a demodulation algorithm, and establishing a first relationship between the phase change amount and the alternating-current voltage signal on the basis of the frequency and amplitude of the alternating-current voltage signal; applying an alternating-current voltage signal having a frequency band below 0.1 Hz, and acquiring the frequency and amplitude of the detection probe (2) via conversion on the basis of the first relationship, so as calibrate a low-frequency performance test of an all-fiber detector. Also provided are a calibration system and apparatus for the low-frequency performance test of the all-fiber detector.

Classes IPC  ?

• G01V 13/00 - Fabrication, étalonnage, nettoyage ou réparation des instruments ou dispositifs couverts par les groupes

Abrégé

Disclosed herein are an animal behavior reconstruction system and method, and an apparatus and a storage medium. The animal behavior reconstruction system comprises at least two cameras, a fixing frame, a timer and a terminal device, wherein the timer is in communication connection with the terminal device and each camera, the terminal device is in communication connection with each camera, and the at least two cameras are respectively arranged at different installation positions of the fixing frame; each camera is configured to receive a waveform signal sent by the timer, collect animal behavior data on the basis of the waveform signal, and send the animal behavior data to the terminal device; and the terminal device is configured to receive and store the animal behavior data sent by the at least two cameras, and determine three-dimensional reconstruction data on the basis of the received animal behavior data.

Classes IPC  ?

• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• G06T 15/00 - Rendu d'images tridimensionnelles [3D]
• H04N 19/00 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques

Abrégé

Disclosed are a small object detection method and apparatus based on feature fusion, a device, and a storage medium. The method comprises: performing size transformation on a pre-obtained low-dimensional input feature map to obtain a high-dimensional feature map; sharing the high-dimensional feature map on a channel domain according to a weight of channels and fusing with high-dimensional semantic information to a spatial domain, and performing sampling again to obtain a resampled feature map; fusing the input feature map and the resampled feature map to obtain a fused feature map; and inputting the fused feature map to a pre-trained object detection model to obtain a small object detection result. According to the present invention, by means of size transformation and resampling, the low-dimensional input feature map is fused with the high-dimensional feature map obtained after size transformation and resampling, thereby facilitating reserving spatial information of a small target object and then improving the accuracy of small target object detection and recognition using an object detection model; moreover, processing parameters are fewer, the amount of calculation is small, and the processing efficiency is higher.

Classes IPC  ?

• G06V 10/771 - Sélection de caractéristiques, p.ex. sélection des caractéristiques représentatives à partir d’un espace multidimensionnel de caractéristiques
• G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
• G06V 10/80 - Fusion, c. à d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification

Abrégé

Disclosed is a thermal management method for a fuel cell. The method comprises: providing an outlet fuzzy controller and an inlet fuzzy controller for a thermal management system for a fuel cell, wherein the thermal management system for a fuel cell comprises a water tank, a cooling water pump, a heat sink, and a stack, the outlet fuzzy controller uses an error between a current stack outlet temperature and a set target outlet temperature and an error change rate as input quantities, and uses a cooling water flow rate as an output quantity, and the inlet fuzzy controller uses an error between a current stack inlet temperature and a set target inlet temperature and an error change rate as input quantities, and uses the rotating speed of a fan of the heat sink as an output quantity; determining membership functions, fuzzy domains, and fuzzy rules of the outlet fuzzy controller and the inlet fuzzy controller; and parameterizing the membership functions, and optimizing the membership functions by means of particle swarm optimization and a genetic algorithm. According to the present invention, the temperature in the thermal management system for a fuel cell can be accurately controlled.

Classes IPC  ?

• H01M 8/04992 - Procédés de commande des éléments à combustible ou des systèmes d’éléments à combustible caractérisés par la mise en œuvre d’algorithmes mathématiques ou de calcul, p.ex. les boucles de commande de rétroaction, la logique floue, les réseaux neuronaux ou l’intelligence artificielle
• H01M 8/04858 - Variables électriques

Abrégé

Provided are a method for preparing a microbial microcapsule and a method for synthesizing a microbial flora (particularly a cross-species microbial flora). According to the principle that chitosan and sodium tripolyphosphate are subjected to a cross-linking reaction, the microcapsule encapsulating microbial bacteria is prepared by means of an electrospray method. A three-dimensional network structure of the microcapsule isolates different microbial bacteria. The semi-permeable membrane property of the microcapsule allows the delivery of a nutrient substance, a metabolite, and a target protein as well as the transport of the target protein, thereby ensuring the requirements for inter-flora signal transmission and substrate transportation. Microcapsules encapsulating different microbial bacteria are further co-cultured to form a microbial flora. The microcapsules with three-dimensional cross-linked structures isolate different microbial bacteria, such that a barrier is established between different species. The composition of the final flora can be regulated and controlled accurately by means of regulating the number of the microcapsules of different species. By means of fusing the microorganisms of different species, the assembly of a series of cross-species floras with labor division, communication, photoautotrophy, and the like can be achieved.

Classes IPC  ?

• C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p.ex. par magnétisme, par des ondes sonores
• C12N 11/10 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un hydrate de carbone
• C12N 11/089 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique obtenu autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• C12N 15/12 - Gènes codant pour des protéines animales
• C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
• C12N 1/19 - Levures; Leurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• C12N 1/21 - Bactéries; Leurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12N 15/31 - Gènes codant pour des protéines microbiennes, p.ex. entérotoxines
• C12N 15/77 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p.ex. Lactobacillus, Micromonospora pour Brevibacterium
• C12N 15/55 - Hydrolases (3)
• C12N 1/38 - Stimulation chimique de la croissance ou de l'activité par addition de composés chimiques qui ne sont pas des facteurs essentiels de croissance; Stimulation de la croissance par élimination d'un composé chimique

Abrégé

The present application relates to the technical field of artificial intelligence. Disclosed in the present application is a brain-computer interface system based on brain-inspired intelligence, comprising a brain-inspired vision module, a brain-inspired data augmentation module, a brain-inspired motion control module, and a brain-inspired movement control module, wherein the brain-inspired vision module performs visual localization, the brain-inspired data augmentation module outputs brain-inspired motion control information and brain-inspired movement control information, and the brain-inspired motion control module and the brain-inspired movement control module control the motion and movement information. Also disclosed in the present application is a brain-computer interface device based on brain-inspired intelligence.

Classes IPC  ?

• B25J 9/00 - Manipulateurs à commande programmée
• G06N 3/02 - Réseaux neuronaux
• B62D 51/00 - Véhicules à moteurs caractérisés par le fait que le conducteur n'est pas assis

Abrégé

Provided are an ovary-targeting polypeptide, a derivative of the polypeptide, and use of the polypeptide in the preparation of a drug or reagent for treating ovarian related reproductive diseases and preventing and treating in-vivo or in-vitro aging of oocytes. The diseases comprise menstrual cycle disorder, polycystic ovary syndrome, androgenic phenotype, hair loss, abnormal metabolism, ovarian insufficiency, premature ovarian failure, ovulation failure, abnormal glucose metabolism, and abnormal lipid metabolism, preferably, hyperglycemia and insulin resistance. In addition, the polypeptide is expected to prolong the preservation time and improve the preservation quality of oocytes or fertilized eggs in the field of assisted reproduction.

Classes IPC  ?

• C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides
• C07K 16/18 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
• C12N 15/12 - Gènes codant pour des protéines animales
• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
• A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
• A61P 3/04 - Anorexigènes; Médicaments de l'obésité
• A61P 3/06 - Antihyperlipémiants
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
• A61P 5/50 - Médicaments pour le traitement des troubles du système endocrinien des hormones pancréatiques pour augmenter ou potentialiser l'activité de l'insuline
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuels; Contraceptifs
• A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c. à d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif

Classes IPC  ?

• A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscience; Dispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p.ex. pour mettre en état d'hypnose

Abrégé

A terahertz near-field audio modulation and demodulation nano-probe array system and method, and a storage medium. On the basis of a terahertz near-field audio modulation and demodulation nano-probe array, the system mixes terahertz wave signals, and demodulates the terahertz wave signals to acquire biomacromolecule information. By means of a terahertz near-field audio modulation and demodulation nano-probe array, fast and dynamic microscopic imaging of biomacromolecules under testing can be realized.

Classes IPC  ?

• G01N 21/3586 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge en utilisant un rayonnement térahertz par spectroscopie térahertz dans le domaine temporel [THz-TDS]
• G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique

Abrégé

A method for characterizing RNA m6A methylation modification, comprising the following steps: (1) extracting total RNA at a low temperature; (2) purifying and enriching to obtain target RNA; and (3) by means of Dotbotting, detecting the m6A methylation level of the target RNA. In step (1), the low temperature is 2-8 °C. An RNA sample is obtained at a low temperature, so that the activity of an enzyme in a tissue and the cell activity can be kept, thereby avoiding the degradation of RNA; by means of controlling the centrifugal speed, the extraction time is shortened; the obtained RNA has high integrity and a high purification rate; and in the RNA denaturation process, by means of controlling the preparation process of a buffer solution in the RNA denaturation process, the detection time is effectively shortened, which further reduces the degradation of RNA.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

The present invention relates to the technical field of man-machine interfaces, and provides a method for identifying a limb movement intention. The method comprises: by means of a light acquisition module, acquiring a plurality of light intensity signals at different positions on a target site of a living body, wherein the light acquisition module comprises: M light sources and N detectors, the M light sources are configured to irradiate the target site, the N detectors are configured to receive light intensity signals emitted from different positions on the target site, M is a positive integer, and N is a positive integer greater than 1; and according to the plurality of light intensity signals, identifying a limb movement intention. The described method can improve the accuracy of identifying the limb movement intention.

Classes IPC  ?

• A61F 2/68 - Moyens d'actionnement ou de commande
• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur

Abrégé

Provided in the present application are a protein rod-shaped body marker and the use thereof. The protein rod-shaped body marker has a hollow rod-shaped structure and is present in an excitatory neurone soma. The protein rod-shaped body structure is related to maintaining the normal physiological function of neurons, and can affect the information transmission function of somatosensory nerves, and therefore can provide a marker or detection standard for the diagnosis and treatment of somatosensory neurological disorder-related diseases.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
• G01N 21/84 - Systèmes spécialement adaptés à des applications particulières

Abrégé

Disclosed in the present application are an encoding method and an encoding device for DNA storage. The method comprises: acquiring a binary sequence to be encoded, wherein the binary sequence comprises N binary units, and N is an integer greater than 0; respectively acquiring base units corresponding to each of N binary units according to a preset mapping rule between binary units and base units, wherein each base unit comprises 7 bases, each binary unit comprises 12 binary digits, the base at position 1 and the base at position 2 in each base unit are different bases, the base at position 6 and the base at position 7 in each base unit are different bases, there are no more than 2 consecutive repetitions of single bases from the base at position 2 to the base at position 6 in each base unit, and the GC content in the base unit is greater than or equal to 0.4 and less than or equal to 0.6; and combining the acquired N base units to acquire a base sequence corresponding to the binary sequence.

Classes IPC  ?

• G16B 30/00 - TIC spécialement adaptées à l’analyse de séquences impliquant des nucléotides ou des aminoacides

Abrégé

Disclosed in the present invention is an image super-resolution method based on an image pre-training strategy. The method comprises: acquiring a target image; and inputting the target image into a trained image super-resolution model, and outputting a super-resolution image, the image super-resolution model sequentially comprising a shallow-feature extraction module, a deep-feature extraction module and a high-resolution reconstruction module, wherein the shallow-feature extraction module extracts shallow features regarding the input target image, the deep-feature extraction module extracts multi-level intermediate features by using a channel attention mechanism and a self-attention mechanism, and the high-resolution reconstruction module uses output features that are from the deep-feature extraction module and output features that are transferred by means of a residual connection and are from the shallow-feature extraction module as inputs, so as to obtain a high-resolution image with respect to the input target image. The present invention improves the performance of image super-resolution in terms of both numerical index and visual effect, and has strong universality.

Classes IPC  ?

• G06T 3/40 - Changement d'échelle d'une image entière ou d'une partie d'image
• G06N 3/08 - Méthodes d'apprentissage
• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion

Abrégé

Use of cordycepin in the preparation of a product for relieving pressure. The cordycepin distributes abnormal body fat. A pharmaceutical composition for relieving pressure, the pharmaceutical composition comprising cordycepin.

Classes IPC  ?

• A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p.ex. nucléosides, nucléotides  contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p.ex. adénosine, acide adénylique
• A61P 3/04 - Anorexigènes; Médicaments de l'obésité
• A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme

Abrégé

A feces-based biomarker of Alzheimer's disease and the use thereof. The biomarker of Alzheimer's disease comprises imidazole propionate. It is detected for the first time that the level of imidazole propionate in a feces sample of a patient with Alzheimer's disease is significantly higher than that in a normal feces sample. Imidazole propionate in the feces sample serves as the biomarker of Alzheimer's disease, and the early diagnosis of Alzheimer's disease can be assisted by detecting the level of imidazole propionate in the feces, which facilitates non-invasive and rapid detection, and has the characteristics of timeliness, convenience, high specificity and high sensitivity.

Classes IPC  ?

• G01N 30/72 - Spectromètres de masse
• G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique

Abrégé

An Alzheimer's disease biomarker and an application thereof. The Alzheimer's disease biomarker comprises any one or a combination of at least two of β-muricholic acid, tauro-β- muricholic acid, ursolic acid, 7-dehydrocholic acid, deoxycholic acid, glycocholic acid-3-sulfate, isodeoxycholic acid, hyodeoxycholic acid or ω-muricholic acid. It is detected for the first time that the level of a specific metabolite in an Alzheimer's disease stool sample is significantly higher than that of a normal stool sample, the specific metabolite in the stool sample is used as the Alzheimer's disease biomarker, and early diagnosis of Alzheimer's disease can be assisted by detecting the level in the stool, thereby facilitating noninvasive rapid detection, and having the characteristics of timeliness, convenience, high specificity and high sensitivity.

Classes IPC  ?

• G01N 30/72 - Spectromètres de masse
• G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique

Abrégé

The present application relates to the technical field of clamping devices, and provided are a clamp and a robotic arm. The clamp comprises a base (100), a rotary driving member (210), a rotary transmission member (220), a first guide gear (310) and two first clamping members (410). The rotary transmission member (220) is mounted on an output shaft (211) of the rotary driving member (210), and is provided with limiting recesses (221). The first guide gear (310) is provided with elastic transmission members (320), and the elastic ends (321) of the elastic transmission members (320) are elastically embedded in the limiting recesses (221). When the acting force applied to the elastic transmission members (320) by the rotary transmission member (220) is greater than or equal to a preset force value, the elastic ends (321) of the elastic transmission members (320) elastically disengage from the limiting recesses (221) and keep abutting against the rotary transmission member (220).

Classes IPC  ?

• B25J 15/02 - Têtes de préhension servocommandées

Abrégé

A biomarker for the early diagnosis of Alzheimer's disease (AD) and a use thereof. In particular, one or more of peripheral blood interleukin 6, peripheral blood CD8+T cells and peripheral blood CD4+T cells act as biomarkers for the early diagnosis of neurodegenerative diseases. A method for the early diagnosis of neurodegenerative diseases, comprising: determining whether an individual is affected by a neurodegenerative disease according to a change in the expression levels of interleukin 6 in peripheral blood and/or a change in the number of CD8+T cells and/or a change in the number of CD4+T cells; and determining the progression of the neurodegenerative disease according to the extent of the elevation of the expression levels of interleukin 6 and/or the severity of abnormalities in CD4+T cells and/or CD8+ T cells in the peripheral blood. AD occurrence and progression is clinically diagnosed by means of detecting biomarkers in the blood, which is low-cost, easy to operate, and low-risk, and which facilitates large-scale screening, thus possessing practical application value.

Classes IPC  ?

• G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
• G01N 33/535 - Production de composés immunochimiques marqués avec un marqueur enzymatique
• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

An artifact correction method and apparatus based on normalizing flow. The method comprises: learning different artifact types and different levels of flow models for data in an image domain and a K-space domain; performing dual learning on the data in the image domain and the K-space domain by using the normalizing flow in the flow models, so as to construct bidirectional reversible mapping between artifact data and artifact-free data; and performing artifact correction on an MRI image by using the bidirectional reversible mapping. Compared with a traditional correction method, due to the reversibility of a flow method, the artifact correction method based on the normalizing flow has better interpretability, and can also have a better artifact correction effect by combining dual domain constraints.

Classes IPC  ?

• G06T 11/00 - Génération d'images bidimensionnelles [2D]
• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”

Abrégé

The present application is applicable to the technical field of voice recognition, and provides an audio classification method and apparatus, a terminal device, and a storage medium. The method comprises: obtaining a spectrogram and a Mel spectrogram of audio data to be classified; according to the spectrogram and the Mel spectrogram, obtaining feature information of said audio data; according to the feature information, classifying said audio data to obtain a classification result of said audio data. The present application can improve the accuracy of audio data classification.

Classes IPC  ?

• G10L 25/18 - Techniques d'analyses de la parole ou de la voix qui ne se limitent pas à un seul des groupes caractérisées par le type de paramètres extraits les paramètres extraits étant l’information spectrale de chaque sous-bande

Abrégé

An information coding method and apparatus based on DNA storage, and a computer device and a medium. The method comprises: acquiring a file, which is stored in the form of a binary sequence (S10); on the basis of a binary-DNA conversion mapping table, segmenting the binary sequence in bytes to obtain binary sequence segments, mapping each binary sequence segment to a base segment, and then sequentially combining all the base segments to form DNA information, wherein each base segment satisfies the following composition conditions: the length is 5; the sum of the number of G bases and the number of C bases is t, which satisfies 0.4 ≤ t/5 ≤ 0.6; there are no repeated bases at a boundary; and there are no three consecutive repeated bases in the middle (S20); and saving the file in the form of DNA information (S30). The method can strictly guarantee that consecutive repeated bases in all coded DNA information have a maximum length of only 2 and a GC content that is between 0.4 and 0.6, an algorithm has linear complexity, and the net information density is 1.60.

Classes IPC  ?

• G16B 50/30 - Entreposage de données; Architectures informatiques
• G06F 16/172 - Mise en cache, pré-extraction ou accumulation de fichiers

Abrégé

Provided are preparation method and use of physical stimulation to control lysis and intracellular substance release of bacteria capable of producing bacterial cellulose. Provided is a plasmid for physically controlling bacterial lysis, wherein the plasmid has a physically activated promoter and a lysis protein-encoding gene amplified under the regulation of the physically activated promoter, a ribosome binding site (RBS) is provided in the upstream of the lysis protein-encoding gene, and the RBS has a sequence set forth in SEQ ID NO: 3 or a sequence having one, two, three, or four base mutations in SEQ ID NO: 3. The problems of self-clearing and intracellular substance release of host bacteria are solved by constructing a lysis system in the host bacteria, which has controllable conditions and high accuracy. The precise regulation of lysis of the engineered bacteria is realized by regulating the RBS site of the lysis protein.

Classes IPC  ?

• C12N 1/21 - Bactéries; Leurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12N 9/90 - Isomérases (5.)
• C12P 19/04 - Polysaccharides, c. à d. composés contenant plus de cinq radicaux saccharide reliés entre eux par des liaisons glucosidiques
• C12R 1/01 - Bactéries ou actinomycètes
• C12R 1/02 - Acetobacter
• C12R 1/05 - Alcaligenes

Abrégé

Disclosed is use of osteocalcin in the preparation of an anti-inflammatory drug. The present invention provides use of osteocalcin in the preparation of a drug used for inhibiting expression and/or release of inflammatory factors of macrophages and/or promoting expression and/or release of anti-inflammatory factors of macrophages. It is found in the present invention that osteocalcin has anti-inflammatory activity, and based on this, use of osteocalcin in the preparation of an anti-inflammatory drug and a drug for treating and/or preventing an inflammation-related disease is proposed in the present invention. By exogenously supplementing osteocalcin, the function of macrophages is specifically adjusted and the release of inflammatory factors is inhibited, so that inflammatory diseases caused by macrophages are prevented and the occurrence and development of inflammation are delayed.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
• A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p.ex. arthrites, arthroses
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
• A61P 3/04 - Anorexigènes; Médicaments de l'obésité
• A61P 1/04 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des ulcères, des gastrites ou des œsophagites par reflux, p.ex. antiacides, antisécrétoires, protecteurs de la muqueuse
• A61P 35/00 - Agents anticancéreux

Abrégé

The present application discloses an autism evaluation method, an autism evaluation apparatus, an electronic device, and a computer storage medium. The autism evaluation method comprises: performing key point identification on a face image of a user to be evaluated to obtain coordinate information of each key point; determining, on the basis of the coordinate information, a symmetry feature of the face of the user to be evaluated, the symmetry feature being used for representing the symmetry of the left cheek and the right cheek of the user to be evaluated; and inputting the symmetry feature into a pre-trained evaluation model to obtain an evaluation result for the user to be evaluated. According to the method, professional medical personnel can be assisted in early screening of ASD.

Classes IPC  ?

• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G06V 40/16 - Visages humains, p.ex. parties du visage, croquis ou expressions
• G06T 7/68 - Analyse des attributs géométriques de la symétrie
• G06V 10/46 - Descripteurs pour la forme, descripteurs liés au contour ou aux points, p.ex. transformation de caractéristiques visuelles invariante à l’échelle [SIFT] ou sacs de mots [BoW]; Caractéristiques régionales saillantes

Abrégé

Disclosed are a multi-channel high-density ultra-narrow stretchable microelectrode, a method for preparing same, and use thereof. The method comprises the following steps: providing a flexible substrate comprising a stretchable area and a rigid area; stretching the stretchable area; sputtering a pattern on the stretched flexible substrate by means of a mask to prepare a conductive layer; releasing the stretchable area to allow a retraction thereof; and packaging to give the multi-channel high-density ultra-narrow stretchable microelectrode. According to the method provided by the present invention, the micro-crack gold film technology is combined with the pre-stretching of the flexible substrate, such that the electrode can be prepared into a multi-channel high-density ultra-narrow electrode, and the good stretching performance and cycling stability of the electrode can be ensured.

Classes IPC  ?

• A61B 5/296 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électromyographie [EMG]
• A61B 5/25 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet
• C23C 14/04 - Revêtement de parties déterminées de la surface, p.ex. au moyen de masques
• A61N 1/04 - Electrodes
• C23C 14/35 - Pulvérisation cathodique par application d'un champ magnétique, p.ex. pulvérisation au moyen d'un magnétron
• H01L 21/285 - Dépôt de matériaux conducteurs ou isolants pour les électrodes à partir d'un gaz ou d'une vapeur, p.ex. condensation

Abrégé

Disclosed in the present invention is a micropore oscillation atomization extractive electrospray ionization device for mass spectrum analysis. Droplet collision and extractive ionization occur in an extractive ionization cavity, so that spraying angles of a sample spraying device and a solvent electrospray device and the spatial positions with a mass spectrometer inlet are fixed, so that the stability and repeatability of extractive electrospray ionization are improved.

Classes IPC  ?

• H01J 49/16 - Sources d'ions; Canons à ions utilisant une ionisation de surface, p.ex. émission thermo-ionique ou photo-électrique
• H01J 49/26 - Spectromètres de masse ou tubes séparateurs de masse

Abrégé

The present application relates to the field of image processing, and specifically relates to a puncture needle real-time detection method and apparatus based on an ultrasonic image. According to the method and the apparatus, the method comprises: cropping, from an obtained image of the inside of a punctured organ, an area containing a puncture needle; segmenting a cropped image by using a trained UNet++ network, so as to obtain an identification position of the puncture needle; performing post-processing on the segmented image by using a small connected domain removal method, so as to obtain a puncture needle accurate positioning area; and performing linear fitting on the pixel points of the puncture needle accurate positioning area, and using a fitting result as a straight line where the puncture needle is located. According to the present application, the puncture needle is detected by using UNet++, and post-processing is performed on a network output result by using a connected domain method, so that the puncture needle detection accuracy and the computing speed are improved; and experiments verify that the computing frequency of a puncture needle real-time detection function can reach 6 Hz. The present application improves the puncture needle detection accuracy and the computing speed by means of an improved neural network and a simplified post-processing method.

Classes IPC  ?

• G06T 7/11 - Découpage basé sur les zones
• G06T 7/136 - Découpage; Détection de bords impliquant un seuillage
• G06T 7/187 - Découpage; Détection de bords impliquant un étiquetage de composantes connexes
• G06T 7/00 - Analyse d'image
• G06N 3/08 - Méthodes d'apprentissage
• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion

Abrégé

Provided are a test case generation method and apparatus, and an electronic device and a storage medium, which are applicable to the field of intelligent tests for autonomous driving. The method comprises: according to a natural driving data set, acquiring a logical scenario parameter set corresponding to an autonomous driving function under test (S101); according to a pre-constructed target proxy model and the logic scenario parameter set, determining an importance sample distribution parameter corresponding to a high-risk driving scenario, wherein the target proxy model is a proxy model for an autonomous driving system under test (S102); and according to the importance sample distribution parameter corresponding to the high-risk driving scenario, generating a target test case (S103). Therefore, a test case that can represent a high-risk driving scenario can be efficiently and accurately generated, such that the testing efficiency of an autonomous driving vehicle is improved.

Classes IPC  ?

• G06F 30/20 - Optimisation, vérification ou simulation de l’objet conçu
• G06F 11/36 - Prévention d'erreurs en effectuant des tests ou par débogage de logiciel

Abrégé

A surgical instrument, behavior and target tissue joint identification method and apparatus. The method comprises: first performing feature category alignment decoupling on surgical instrument, behavior and target tissue sub-tasks in a scene by using a category-aligned channel attention mechanism (S100); then introducing a long short-term memory network to perform spatial-temporal feature fusion on action information of the surgical instrument, behavior and target tissue sub-tasks in the scene after the feature category alignment decoupling (S200); and identifying the surgical instrument, behavior and target tissue sub-tasks after the spatial-temporal feature fusion by means of a fully connected layer (S300). By extracting local diversity fine-grained features in a surgical scene, more sufficient spatial feature description is achieved, accurate identification under multi-instrument and multi-target conditions in a surgical operation is achieved by means of category decoupling, and automatic real-time analysis of the key content of an accurate and specific surgical scene is comprehensively achieved.

Classes IPC  ?

• G06V 20/52 - Activités de surveillance ou de suivi, p.ex. pour la reconnaissance d’objets suspects
• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion
• G06V 10/80 - Fusion, c. à d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux

Abrégé

Disclosed in the present invention are an automatic electrospray spraying apparatus and method for preparing a mass spectrum imaging sample. The automatic electrospray spraying apparatus for preparing a mass spectrum imaging sample comprises: a spray capillary; an injection mechanism, an outlet end of which communicates with an inlet end of the spray capillary; a high-voltage power source, which is electrically connected to the spray capillary; and a mechanical arm, which is used for driving the spray capillary to move. In the present solution, micron-sized tiny fogdrops are generated by means of the electrospray principle, such that the spraying of a derivatization reagent and a matrix can be realized; and compared with the prior art, the present solution has an order-of-magnitude improvement in the degree of fineness of liquid droplets, it is guaranteed that a derivatization reaction does not destroy in-situ information, and it is also guaranteed that crystal grain of matrix crystallization have a small size and uniform distribution, thereby ensuring the mass spectrum imaging quality. In addition, in the present solution, a mechanical arm is further used for operating a spraying process, such that the spraying process is more flexible, the efficiency is higher, and the reagent can be automatically sucked and replaced, thereby realizing full-automatic sample preparation for multi-reagent spraying, such as superposed spraying of the derivatization reagent and the matrix.

Classes IPC  ?

• H01J 49/16 - Sources d'ions; Canons à ions utilisant une ionisation de surface, p.ex. émission thermo-ionique ou photo-électrique
• H01J 49/26 - Spectromètres de masse ou tubes séparateurs de masse

Abrégé

Disclosed in embodiments of the present application are a method and apparatus for determining a loss model of a radio frequency transmitting coil, and a device and a medium. The method comprises: obtaining first index data of at least two evaluation indexes of scattering parameters of each of at least one transmitting channel of a radio frequency transmitting coil of a magnetic resonance system in an actual measurement environment; connecting an equivalent resistor in parallel or in series for each circuit component of a virtual radio frequency transmitting coil so as to establish a loss simulation model; and adjusting an equivalent resistor and a matching capacitor of each transmitting channel in the loss simulation model to enable an error between second index data of the at least two evaluation indexes of the scattering parameters of each transmitting channel in the loss simulation model after adjustment and the corresponding first index data to be within a corresponding threshold range so as to obtain a loss model of the radio frequency transmitting coil.

Classes IPC  ?

• G06F 30/20 - Optimisation, vérification ou simulation de l’objet conçu

Abrégé

Disclosed in the present application is a method for measuring an elastic constant of a fiber reinforced plastic (FRP) material. The method comprises: providing a one-way slab prepared from an FRP material; making an ultrasonic wave incident on a first side of the one-way slab, and receiving, on the first side, the ultrasonic wave reflected by a second side, so as to obtain the actually measured propagation time of the ultrasonic wave in the one-way slab, wherein the first side and the second side are opposite sides of the one-way slab; calculating the theoretical propagation time of the ultrasonic wave in the one-way slab; and taking the sum of squared errors between the actually measured propagation time and the theoretical propagation time as an objective function, and performing back calculation by means of particle swarm optimization to obtain an elastic constant value until the objective function is minimized. In this way, in the present application, an elastic constant of an FRP material can be obtained by means of measurement, and there is no need to immerse an FRP one-way slab in water or rotate the FRP one-way slab, such that the in-situ nondestructive measurement of the elastic constant of the FRP material is realized.

Classes IPC  ?

• G01N 29/07 - Analyse de solides en mesurant la vitesse de propagation ou le temps de propagation des ondes acoustiques

Abrégé

The present application provides a method for evaluating the generalization ability of a deep super-resolution network. The method comprises: for a super-resolution model, selecting a reference data set (S110), the performance of the super-resolution model on the reference data set being known; respectively inputting the reference data set and a target data set to be measured into the super-resolution model to obtain a corresponding reference deep statistical characteristic and a corresponding target deep statistical characteristic (S120); performing dimension reduction on the obtained reference deep statistical characteristic and target deep statistical characteristic (S130); respectively fitting the dimension-reduced reference deep statistical characteristic and target deep statistical characteristic to a set distribution (S140), so as to obtain distribution parameters reflecting data distribution characteristics; and calculating a distance between a distribution corresponding to the reference data set and a distribution corresponding to the target data set (S150), so as to evaluate the generalization of the super-resolution model. According to the present invention, on the basis of deep statistical characteristics in a network, image content and degradation are decoupled, and a non-parametric and non-learning generalization evaluation index having high interpretability is provided.

Classes IPC  ?

• G06T 3/40 - Changement d'échelle d'une image entière ou d'une partie d'image
• G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”

Abrégé

The present application belongs to the technical field of ionomer synthesis, and particularly relates to a sulfonated benzene polyphenyl ionomer and a method for preparing same, and a proton exchange membrane. The main chain of a precursor polymer adopted by the method for preparing the sulfonated benzene polyphenyl ionomer described herein contains the structural unit of benzil or diphenylacetone, providing conditions for a reaction of the precursor polymer with a first monomer and a reaction of the precursor polymer with a second monomer, and the method features simple synthesis, low cost, and easy regulation and control.

Classes IPC  ?

• C08G 61/10 - Composés macromoléculaires contenant uniquement des atomes de carbone dans la chaîne principale de la molécule, p.ex. polyxylylènes uniquement des atomes de carbone aromatiques, p.ex. polyphénylènes
• H01M 8/1023 - Matériaux d’électrolyte polymère caractérisés par la structure chimique de la chaîne principale du polymère conducteur ionique comprenant uniquement du carbone, p.ex. des polyarylènes, des polystyrènes ou des polybutadiène-styrènes
• H01M 8/1072 - Matériaux d’électrolyte polymère caractérisés par le procédé de fabrication par des réactions chimiques, p.ex. polymérisation in situ ou réticulation in situ

Abrégé

The present application relates to the technical field of batteries, and in particular to a carbon/Berlin blue-like composite material and a preparation method therefor and use thereof. The preparation method comprises the following steps: preparing a carbon material, a chelating agent and a transition metal salt into a first mixture dispersion liquid, and carrying out a first hydrothermal reaction to obtain a carbon-transition metal composite precursor; and preparing alkali metal-ferrocyanide and the carbon-transition metal composite precursor into a second mixture dispersion liquid, carrying out a second hydrothermal reaction, and carrying out post-treatment to obtain the carbon/Berlin blue-like composite material. According to the preparation method, by means of a hydrothermal method, a solid-phase precursor is firstly synthesized. The rate of the carbon-transition metal composite precursor in the conversion process is relatively low, facilitating the slow formation of Berlin blue-like crystal lattices, and reducing the structural defects of ferrocyanide vacancy and crystal water easily occurring in the Berlin blue-like synthesis process. Meanwhile, the carbon material is provided for uniform compounding, so that the electrical conductivity is improved, the cycle performance and the stability are improved, and the method is suitable for large-scale production.

Classes IPC  ?

• C01C 3/12 - Cyanures de fer simples ou complexes
• C01B 32/184 - Préparation
• C01B 32/00 - Carbone; Ses composés
• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p.ex. phosphates, silicates ou borates
• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p.ex. liants, charges
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p.ex. au magnésium ou à l'aluminium

Abrégé

The present application is suitable for the field of biological medicine. Provided are an active peptide fragment generating method, apparatus and device and a storage medium. The active peptide fragment generating method comprises: acquiring a peptide fragment generating model corresponding to a specific activity, the peptide fragment generating model being obtained by training an LSTM network by using a universal peptide data set and a preset active peptide data set corresponding to the specific activity, the universal peptide data set comprising a plurality of universal peptide fragments; and, by using the peptide fragment generating model, generating a plurality of peptide fragments having the specific activity. In the solution, the peptide fragment generating model is obtained by training the LSTM network by using the universal peptide data set and the preset active peptide data set corresponding to the specific activity, and, during the training process, the model can learn potential features of the universal peptide fragments and potential activity rules of known active peptide fragments. Therefore, during a process of actually using the peptide fragment generating model, peptide fragments having different specific activities and rich diversity can be generated according to different specific activity requirements.

Classes IPC  ?

• G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients

Abrégé

The present application discloses a generation method and generation apparatus for a tumor radiotherapy region. The generation method for a tumor radiotherapy region comprises: acquiring a first CT image actually obtained during a treatment process of a target object and a second CT image initially obtained before the treatment; in response to an external input instruction, marking the position of a first control region on the second CT image to generate a third CT image; obtaining a first translation parameter and a first rotation parameter by means of inputting the first CT image and the third CT image into a dense network model; transforming the first CT image according to the first translation parameter and the first rotation parameter to generate a fourth CT image, wherein the fourth CT image is an image provided with a target control region for the radiotherapy of the target object.

Classes IPC  ?

• G06T 7/30 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images

Abrégé

A spiking neural network-based data enhancement method and apparatus. The method is applied to implantable brain-computer interface data, and can extract information distribution characteristics under a condition of limited neural information data; on the basis of biological attributes of a spiking neural network, the method is suitable for learning the distribution characteristics of neural information, so that a neural signal conforming to the information distribution characteristics is generated, and the neural signal serves as brain information data enhancement; the method considers cluster activity characteristics of biological neurons, and uses the cluster activity characteristics as a data enhancement basis, and the spiking neural network has biological properties, and is suitable for directly generating neural information, so that brain-computer interface information is enhanced, and the method has a great significance for research and application of brain-computer interfaces.

Classes IPC  ?

• G06N 3/063 - Réalisation physique, c. à d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques

Abrégé

The present application relates to the technical field of image processing, and provides an image segmentation method and apparatus, a terminal device, and a storage medium. The image segmentation method comprises: obtaining an image to be processed; inputting said image into a trained image segmentation model for processing, and outputting a segmented image, wherein the image segmentation model is of an encoder-decoder structure, a group integration module is arranged between an encoder and a decoder corresponding to each other, the group integration module is used for extracting m pieces of compensation information of different scales from input features of the encoder and inputting the m pieces of compensation information of different scales into the decoder, and m is greater than or equal to 2. According to the image segmentation method and apparatus, the terminal device and the storage medium provided by the present application, the problem that image segmentation results of the existing image segmentation methods are inaccurate can be solved to a certain extent.

Classes IPC  ?

• G06V 10/26 - Segmentation de formes dans le champ d’image; Découpage ou fusion d’éléments d’image visant à établir la région de motif, p.ex. techniques de regroupement; Détection d’occlusion
• G06N 3/04 - Architecture, p.ex. topologie d'interconnexion

Abrégé

A shimming joint simulation method and apparatus, an electronic device, and a storage medium. The method comprises: obtaining initial simulation data generated by simulation software executing an electromagnetic simulation operation on the basis of initial configuration data, performing shimming analysis on the initial simulation data to obtain target amplitude-phase data, and sending the target amplitude-phase data to the simulation software; obtaining power loss density distribution data corresponding to the target amplitude-phase data determined by the simulation software, and determining specific absorption rate data corresponding to the power loss density distribution data; and in response to the specific absorption rate data being greater than or equal to a preset threshold, generating current amplitude-phase data on the basis of a preset iteration interval by taking the target amplitude-phase data as a starting point, controlling the simulation software to execute the electromagnetic simulation operation again on the basis of the current amplitude-phase data to obtain current initial simulation data, and returning to the step of performing shimming analysis on the initial simulation data.

Classes IPC  ?

• G06F 30/20 - Optimisation, vérification ou simulation de l’objet conçu

Abrégé

Disclosed in the present application is a video super resolution method. The method comprises: acquiring an original video frame sequence containing at least two original video frames; and performing video super resolution operation on the original video frame sequence by means of a pre-trained target multi-scale video super resolution model, and outputting a target video frame sequence containing a target video frame, the target multi-scale video super resolution model comprising a multi-scale feature interaction network and an image reconstruction network.

Classes IPC  ?

• G06T 3/40 - Changement d'échelle d'une image entière ou d'une partie d'image

Abrégé

Disclosed are a method for predicting an interaction relationship of a drug pair, and a device and a medium, which are applicable to the technical field of biomedicine. The method comprises: acquiring a target text, the target text comprising a plurality of drugs, and each drug appearing at least once in the target text (S201); respectively determining a comprehensive entity representation corresponding to each drug, the comprehensive entity representation being used for describing semantic information of the corresponding drug at each position in the target text (S202); with regard to any drug pair among the plurality of drugs, determining a fusion entity representation of the drug pair according to the comprehensive entity representation of two drugs in the drug pair (S203); and according to the fusion entity representation of the drug pair, predicting the interaction relationship of the drug pair (S204). By means of the method, the accuracy of predicting the interaction relationship of each drug pair in a document can be improved.

Classes IPC  ?

• G16H 70/40 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des médicaments, p.ex. leurs effets secondaires ou leur usage prévu

Abrégé

Disclosed in the present invention are a feature selection method, a feature selection apparatus, and a storage medium. The method comprises: calculating the fitness of each sample in a current generation population; screening for some samples according to the fitness to form an operation sample group; replacing a sample having the fitness smaller than a first threshold in the operation sample group with a sample having the fitness greater than a second threshold to form a first sample group; collecting statistics about distribution probabilities of feature values, at each feature bit, of samples in the first sample group, and sampling according to the distribution probabilities to generate new feature values at each feature bit to form a second sample group; performing multiple crossover operations on the operation sample group to form a third sample group; performing a mutation operation on the operation sample group to obtain a fourth sample group; combining the sample groups to form a next generation population; and when an evolution termination condition is met, outputting features corresponding to the last generation population. More high-fitness new samples are generated by means of high-fitness samples, thereby facilitating search for a globally optimal feature subset.

Classes IPC  ?

• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06V 10/771 - Sélection de caractéristiques, p.ex. sélection des caractéristiques représentatives à partir d’un espace multidimensionnel de caractéristiques

Abrégé

3333 perovskite quantum dot. According to the preparation method of the present application, the organic carboxylic acid, i.e. oleic acid, and the organic amine, i.e. oleylamine, are used as synergistic passivation ligands to effectively reduce the surface defect concentration; in addition, the short-chain organic carboxylic acid is introduced to inhibit the crystal nucleation speed and inhibit the agglomeration between the quantum dots, thereby forming a ligand protection layer on the surfaces of the quantum dots, so that the stability and the light-emitting property of the perovskite quantum dots are improved.

Classes IPC  ?

• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension
• C09K 11/66 - Substances luminescentes, p.ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du germanium, de l'étain ou du plomb
• B82Y 20/00 - Nano-optique, p.ex. optique quantique ou cristaux photoniques
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• H01L 51/42 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement
• H01L 51/46 - Emploi de matériaux spécifiés

Abrégé

An epilepsy drug treatment outcome prediction method and apparatus. The method comprises: acquiring a plurality of modes of magnetic resonance images of TSC patients before performing anti-epileptic drug treatment (S1); randomly dividing the TSC patients into a training set and a test set according to a ratio (S2); performing regional segmentation on the each mode of magnetic resonance image on the basis of a U-net++ network to obtain regions of interest (S3); performing feature extraction on each region of interest to obtain high-dimensional radiomics features (S4); performing analysis and screening on the high-dimensional radiomics features to obtain target radiomics features (S5); using a machine learning algorithm to train a prediction model for the target radiomics features in the training set to construct an epilepsy drug treatment outcome prediction model and verifying said model in the test set (S6); and using the constructed epilepsy drug treatment outcome prediction model to predict a target radiomics feature of a patient to be treated to obtain a predicted epilepsy drug treatment outcome (S7). The method can rapidly and effectively predict a drug treatment outcome of an epilepsy patient, thus assisting a doctor in formulating a better treatment scheme.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus

Abrégé

A pupil mask for generating a thin and wide light sheet and an optimized design method therefor. A thin and wide light sheet is crucial to a light sheet microscope having a large field of view and near diffraction-limited resolution. A non-diffracting light sheet is very wide in span range, but generally has a strong side lobe or an increased thickness. The pupil mask is designed according to a numerical optimization method so as to generate the thin and wide light sheet, so that a contradiction among the thickness of the light sheet, a non-diffraction range, and a side lobe is relieved. A theory and an experiment show that an optimized mask expands the non-diffraction range of a static light sheet by 50%, and enables the side lobe thereof to be lower than 20%; and the generated static light sheet can perform larger field-of-view imaging on a sample without sacrificing axial resolution.

Classes IPC  ?

• G02B 27/00 - Systèmes ou appareils optiques non prévus dans aucun des groupes ,
• G02B 21/06 - Moyens pour éclairer un échantillon

Abrégé

A human body motion monitoring method based on multi-source information fusion. Different human physiological structure characteristics of individuals are considered, and multi-source information is collected, comprising human body metrology information, plantar pressure distribution data, and an actual inertial measurement unit attachment position and collected data, so that the human skeleton model for calculation better conforms to a real subject. By means of establishing an objective function and constraint for improving the precision of the inertial measurement unit and meeting the athletic physiological significance of a human body, and by means of performing minimum optimization calculation on the objective function, a joint motion parameter can be obtained. The human body motion monitoring method based on multi-source information fusion can reduce the problem and error of human body model uncertainty caused by factors such as a sensor error, mechanical joint hypothesis, skin deformation, and the like, and improve the monitoring precision of joint motion. Because a detection environment does not need to be arranged, high-precision human body motion monitoring with physiological significance in a daily motion environment can be conveniently achieved, comprising human body motion analysis under a pathological condition with a high-precision requirement.

Classes IPC  ?

• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux