Additive manufacturing methods, additive manufacturing systems, and products thereof are provided. The method comprises depositing a bioink into a support material based on a first computer model of an object, thereby forming a first portion of an object in the support material. The bioink comprises cells. The method comprises depositing a structure material into the support material based on the first computer model of an object, thereby forming a first portion of a scaffold for the object. The structure material is different from the bioink and the structure material comprises a polymer. The method comprises repeating the depositing of the bioink and the structure material as necessary to additively form the object and the scaffold within the object.
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux
A method of synthesizing a polynucleotide composition includes performing a synthesis of the polynucleotide composition via phosphoramidite chemistry, solid-phase supported synthesis, to create polynucleotide chain. During at least one cycle of the synthesis, coupling an RDRP-phophoramidite reagent in a growing chain of the polynucleotide composition. The RDRP -phophoramidite reagent, includes a phosphoramidite compound conjugated to an RDRP initiator or a chain transfer agent for RDRP via a moiety comprising a protected hydroxyl group. A hydroxyl protecting group of the protected hydroxyl group is stable to polynucleotide synthesis conditions.
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p.ex. pour test de réaction en chaîne par polymérase [PCR]
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques avec le ribosyle comme radical saccharide
3.
POST-SYNTHETIC MODIFICATION OF POLYNUCLEOTIDES VIA ACYLATION REAGENTS
A method of modifying a polynucleotide includes reacting the polynucleotide with one or more molecules of an acylating reagent. The acylating reagent includes an acylating compound conjugated to (i) an initiator compound for reversible deactivation radical polymerization; (ii) a chain transfer agent for reversible deactivation radical polymerization or (iii) a compound comprising a polymerizable group to form a modified polynucleotide.
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques avec le ribosyle comme radical saccharide
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
Disclosed herein is a system and method implementing a processing and detection pipeline to detect spreading depolarization waves in a brain occurring after a traumatic brain injury. The method relies solely on EEG data collected by a standard EEG machine.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 30/00 - TIC spécialement adaptées au maniement ou au traitement d’images médicales
5.
SIMULATING DYNAMIC SOLAR HARVESTING WITH MODELLING OF DIFFUSE SHADOWS
Disclosed herein is a novel method for modelling and simulating urban solar harvesting by modeling the components of solar radiation using a modelling framework with modules related to view factors, transmittance, beam and diffuse shadow modeling, heat transfer equilibrium, and a virtual environment that emulates urban infrastructure and receives weather and radiation data as inputs. Also disclosed herein are various approaches for modelling diffuse shadows, which are a component of the integrated modelling framework. The various modules are integrated and optimized to compose several versions of modeling and simulation tools, which can estimate the temperature, power, and energy output of dense groups of freely-defined dynamic solar harvesting surfaces in urban and other intricate scenarios characterized by high three-dimensionality.
Disclosed herein is a co-designed compiler and CGRA architecture that achieves both high programmability and extreme energy efficiency. The architecture includes a rich set of control-flow operators that support arbitrary control flow and memory access on the CGRA fabric. The architecture is able to realize both energy and area savings over prior art implementations by offloading most control operations into a programmable on-chip network where they can re-use existing network switches.
Disclosed herein is a high-density storage system comprising a plurality of layers, each layer comprising a plurality of rows for storing a plurality of coupled totes and one or more carriers located on opposite ends of each layer, each carrier being multiple rows wide, each carrier capable of retrieving totes from a row in the layer, depositing a tote into a row or oral in a layer and shifting totes from one row to another within the layer.
B65G 1/06 - Dispositifs d'emmagasinage mécaniques avec des moyens pour que les objets se présentent à l'enlèvement dans des positions ou à des niveaux prédéterminés
B65G 1/137 - Dispositifs d'emmagasinage mécaniques avec des aménagements ou des moyens de commande automatique pour choisir les objets qui doivent être enlevés
B65G 41/00 - Châssis ou bases de support pour transporteurs dans leur ensemble, p.ex. châssis transportables
B65D 21/028 - Réceptacles de forme spéciale ou pourvus de garnitures ou de pièces de fixation, pour faciliter l'emboîtement, le gerbage ou l'assemblage pour empiler des réceptacles placés sur le côté, ou pour réunir des réceptacles côte à côte, par des moyens situés latéralement quand les réceptacles sont orientés normalement avec des moyens de liaison faisant partie intégrante des réceptacles, p.ex. queues-d'aronde, encliquetages ou crochets
B65G 1/00 - Emmagasinage d'objets, individuellement ou avec une certaine ordonnance, dans des entrepôts ou des magasins
B65G 1/16 - Disposition particulière des objets dans les aires de stockage
B65G 47/90 - Dispositifs pour saisir et déposer les articles ou les matériaux
8.
BIODEGRADABLE HYDROGEL ACTUATOR WITH SHAPE MORPHING CAPABILITY FOR SOFT ROBOTICS AND METHODS OF FABRICATION
A morphing, biologically-derived actuator can be used with soft robotics in a marine environment. The actuator is fabricated using a modified hydrogel additive manufacturing printing process, where the printed structure is exposed to various concentrations of crosslinking initiator to ensure a water-tight seal between adjacent printed layers. The actuator fabricated using the disclosed process is suitable for marine use and is safe for marine animals and is biodegradable.
C08J 3/02 - Production de solutions, dispersions, latex ou gel par d'autres procédés que ceux utilisant les techniques de polymérisation en solution, en émulsion ou en suspension
B25J 19/00 - Accessoires adaptés aux manipulateurs, p.ex. pour contrôler, pour observer; Dispositifs de sécurité combinés avec les manipulateurs ou spécialement conçus pour être utilisés en association avec ces manipulateurs
B32B 27/28 - Produits stratifiés composés essentiellement de résine synthétique comprenant des copolymères de résines synthétiques non complètement couverts par les sous-groupes suivants
B32B 27/08 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique d'une résine synthétique d'une sorte différente
9.
METHOD FOR PRODUCTION OF VIRUS-LIKE PARTICLES FOR GENE DELIVERY
Methods for production of gene-delivery vectors suitable for animal models and humans using a bacteria/mammalian dual-expression plasmid, wherein the virus-like particles may be massively produced via heterologous expression in bacteria. Also provided are methods of increasing virus-like particle transduction efficiency and methods of directed evolution.
A capacitive sensor system is adapted for use as a wearable sensor and is capable of measuring the muscle activity of a user. The sensor system monitors the change in distance between an electrode and the user's skin, where the change is caused by the changing muscle cross-sectional area or muscle bulging. A musculoskeletal model is used to validate the capacitance measurement with the muscle cross-sectional area from gold-standard marker-based motion capture along with gold-standard measurements of muscle excitation, and muscle contraction force. The sensor can be used in real-world settings to assist with gait rehabilitation, among other uses.
A clinical decision support system and method for patients with pulmonary arterial hypertension is disclosed herein. The system may comprise a processor to process instructions to execute one or more pulmonary arterial hypertension risk algorithms configured to generate a risk score value associated with a patient surviving within a given time period. The system may comprise a means for input and output, wherein input variable data may be received and a set of risk score values may be displayed. A method for operating the clinical decision support system is also disclosed.
G06N 20/20 - Techniques d’ensemble en apprentissage automatique
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
12.
METHOD AND SYSTEM TO IDENTIFY NATURAL PRODUCTS FROM MASS SPECTROMETRY AND GENOMICS DATA
A method and system is for receiving data representing gene clusters, the gene clusters including one or more genes configured to encode one or more polypeptides or other small molecules; accessing a machine learning model, the machine learning model being trained with a training dataset that associates the gene clusters to structures of one or more small molecules represented in the data; applying the machine learning model to the data representing the gene clusters; identifying, based on applying the machine learning model, one or more monomers associated with at least one gene cluster represented in the data; and determining a structure for a natural product including the one or more monomers.
A needle for mass spectrometry having a solid shaft and a first end with a tip having a radius of curvature of less than 1500 nm, wherein the tip is distal from a second end of the needle, wherein the second end is configured to accept an electrical potential, and wherein the tip provides an ionization region when the electrical potential is applied. Methods of manufacturing a needle having a radius of curvature of less than 1500 nm. Methods and systems including at least one needle of the present disclosure for qualitative and/or quantitative analysis.
Disclosed herein is a nanostructured composite thermal interface and a method for fabricating the interface. The interface consists of a metal foil having arrays of metal nanowires disposed on either side thereof. An adhesive polymer is interspersed within the nanowires in each array and serves as a binder to adhere the interface to the surfaces of target objects, for example, a CPU and a heat sink.
Disclosed herein is a method for fabricating a nanowire array on an uneven or curved surface. A pliable, porous scaffold is used to hold a liquid electrolyte, creating s semi-solid electrolyte that is used to transfer pressure to a template disposed on the target surface to cause the template to conform to and bond with the target surface to substantially eliminate the gap therebetween, such that a robust and controllable growth of the nanowire array can be realized.
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p.ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p.ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p.ex. PEG, PPG, PEO ou polyglycérol
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p.ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénal
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
An oxygenation system producing oxygen for therapeutic cells housed in an implanted or external device, the oxygenation system comprising a first electrode comprising a first material layer stack and a catalyst film of a high surface area or catalyst particles on which at least one catalyst for electrocatalytic oxygen evolution reaction is disposed; and a second electrode comprising a second material stack.
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
C25B 11/073 - PROCÉDÉS ÉLECTROLYTIQUES OU ÉLECTROPHORÉTIQUES POUR LA PRODUCTION DE COMPOSÉS ORGANIQUES OU MINÉRAUX, OU DE NON-MÉTAUX; APPAREILLAGES À CET EFFET Électrodes; Leur fabrication non prévue ailleurs caractérisées par le matériau Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique
C25B 9/73 - Assemblages comprenant plusieurs cellules du type filtre-presse
C25B 15/08 - Alimentation ou vidange des réactifs ou des électrolytes; Régénération des électrolytes
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
18.
METHOD FOR FOCUSED TRANSCRANIAL ELECTRICAL CURRENT STIMULATION
Disclosed herein is a method for optimizing electrode placement that directly exploits the thresholding phenomenon of neurons. The method employs a loss function which only becomes non-zero when the electric field is above a user- specified threshold in the cancel region, thereby allowing for fields which can have significant non-zero current in the cancel region, but still provide more focused neural activation.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio
A61B 5/25 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet
A61B 5/369 - Modalités, c. à d. méthodes diagnostiques spécifiques Électroencéphalographie [EEG]
Provided is a system and method for holographic light curtains. A system includes a holographic projector configured to project a holographic image, a rolling-shutter camera arranged to receive light from the holographic image, and at least one processor in communication with the rolling-shutter camera, the at least one processor programmed or configured to: determine an intensity of the light received from the holographic image; and detect a disturbance in a space of the holographic image based on a change in the intensity.
G03H 1/04 - Procédés ou appareils pour produire des hologrammes
G01S 17/04 - Systèmes de détermination de la présence d'une cible
G03H 1/00 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une image; Leurs détails spécifiques
G03H 1/02 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une image; Leurs détails spécifiques - Détails
H04N 23/68 - Commande des caméras ou des modules de caméras pour une prise de vue stable de la scène, p. ex. en compensant les vibrations du boîtier de l'appareil photo
H04N 23/80 - Chaînes de traitement de la caméra; Leurs composants
G02B 27/09 - Mise en forme du faisceau, p.ex. changement de la section transversale, non prévue ailleurs
G03H 1/22 - Procédés ou appareils pour obtenir une image optique à partir d'un hologramme
Disclosed herein are devices comprising stretchable interdigitated electrode arrays and methods for fabricating the devices. The devices are capable of acting as elongation sensors by sensing a change in the capacitance of the device as the distance between the interdigitated fingers changes when the device is elongated or compressed. The device may be coupled to other devices such as to be able to sense elongation or compression of the coupled device. The interdigitated fingers of the device are supported by a substrate and may be fabricated using traditional microfabrication techniques.
G01B 7/16 - Dispositions pour la mesure caractérisées par l'utilisation de techniques électriques ou magnétiques pour mesurer les déformations dans un solide, p.ex. au moyen d'une jauge de contrainte à résistance
G01B 1/00 - Instruments de mesure caractérisés par l'usage d'un matériau spécifique
Disclosed herein is a novel design of an instrumented cochlear implant, wherein the electrode array portion of the implant is provided with a microfabricated thin-film sensing array comprising one or more sensors to detect various features of the electrode array during insertion and to provide feedback to the surgeon during implantation. The sensing array collects intraoperative information on the state of the electrode array during insertion.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
22.
SYSTEM AND METHOD FOR WEAPON DETECTION WITH POSE ESTIMATION
Disclosed herein is an artificial intelligence-based system and method for detecting possible danger in a scene contain one or more people. Individual people are detected and it is determined if one of the person's limbs is in a threatening position and if the hand of the person is holding a weapon. The system uses neural networks to detect people and weapons and classifiers to determine a probability of danger, based on the evaluation of the position and state of the limbs of the person.
Disclosed herein is a system for analyzing data extracted from an instrumented cochlear implant, wherein the electrode array portion of the implant is provided with a microfabricated thin-film sensing array comprising one or more sensors to detect various features of the electrode array during insertion and to provide feedback to the surgeon during implantation. Preferred embodiments of the system utilize one or more trained machine learning models to extract features from the raw data received from the sensing array and can perform a pose estimation of the electrode array and recommend next surgical actions to increase the probability of a positive clinical outcome.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
24.
TRAINING SYSTEM FOR SIMULATING COCHLEAR IMPLANT PROCEDURES
Disclosed herein is a cochlear implant surgery simulator and training system. The system comprises a 3D model of a scala tympani upon which a surgeon performs practice insertions an the electrode array of a cochlear implant, wherein the electrode array is instrumented with one or more thin-film sensors disposed along a length of the electrode array, enabling real-time collection of force and position data. The system further comprises a feedback system for analyzing data collected from the instrumented electrode array and deriving scoring metrics regarding the surgeon's insertion technique.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
Disclosed herein is a system and method for implementing object detection and identification, regardless of the orientation of the object. The product detection and recognition method and system disclosed herein comprises capturing views of each object from different angles from a plurality of cameras and fusing the result of a matching process to identify the object as one of a plurality of objects enrolled in an object database.
A method of detecting bacteria. An example aspect is configured to: provide at least one peptide comprising the amino acid sequence as set forth in any one of SEQ ID NOS: 1-46; attach a label to the at least one peptide to form a labeled peptide; add the labeled peptide to an aqueous sample; and detect a qualitative or quantitative signal in the aqueous sample, the signal indicating a presence of at least one gram-positive or at least one gram-negative bacteria. A peptide capable of binding to at least one cell wall carbohydrate ligand on a cell wall surface of at least one bacteria, the peptide having an amino acid sequence as set forth in any one of SEQ ID NOS: 1-46.
G01N 33/58 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des substances marquées
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
27.
SYSTEM AND METHOD FOR ON-DEMAND SEPARATED I/O CHANNELS
Disclosed herein is a system and method to provide secured I/O channels for multiple types of I/O devices to isolated applications, on-demand. The invention enables composition of different I/O kernels and, as such, eliminates developer effort required to re-implement and re-verify new I/O kernels to protect multiple types of I/O devices.
G06F 21/44 - Authentification de programme ou de dispositif
G06F 9/455 - Dispositions pour exécuter des programmes spécifiques Émulation; Interprétation; Simulation de logiciel, p.ex. virtualisation ou émulation des moteurs d’exécution d’applications ou de systèmes d’exploitation
G06F 21/53 - Contrôle des usagers, programmes ou dispositifs de préservation de l’intégrité des plates-formes, p.ex. des processeurs, des micrologiciels ou des systèmes d’exploitation au stade de l’exécution du programme, p.ex. intégrité de la pile, débordement de tampon ou prévention d'effacement involontaire de données par exécution dans un environnement restreint, p.ex. "boîte à sable" ou machine virtuelle sécurisée
G06F 21/57 - Certification ou préservation de plates-formes informatiques fiables, p.ex. démarrages ou arrêts sécurisés, suivis de version, contrôles de logiciel système, mises à jour sécurisées ou évaluation de vulnérabilité
28.
SCALABLE FABRICATION OF MICRODEVICES FROM METALS, CERAMICS, AND POLYMERS
A method for manufacturing a structure having at least one microscale feature includes mixing a powdered material with a binder to yield a slurry, shaping the slurry to yield a green device, and sintering the green device to yield the structure.
B22F 3/00 - Fabrication de pièces ou d'objets à partir de poudres métalliques, caractérisée par le mode de compactage ou de frittage; Appareils spécialement adaptés à cet effet
C04B 35/00 - Produits céramiques mis en forme, caractérisés par leur composition; Compositions céramiques; Traitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques
C04B 35/622 - Procédés de mise en forme; Traitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques
C04B 35/626 - Préparation ou traitement des poudres individuellement ou par fournées
B29C 33/38 - Moules ou noyaux; Leurs détails ou accessoires caractérisés par la matière ou le procédé de fabrication
B29C 33/42 - Moules ou noyaux; Leurs détails ou accessoires caractérisés par la forme de la surface de moulage, p.ex. par des nervures ou des rainures
B81C 1/00 - Fabrication ou traitement de dispositifs ou de systèmes dans ou sur un substrat
29.
SYSTEM FOR ROBOTIC CHARACTERIZATION OF IMPACTED SITES
A mobile testing and evaluation vehicle can include a body and a mobility feature disposed on the body, where the mobility feature is configured to move the body with respect to a zone of interest. The mobile testing and evaluation vehicle can also include a sensor device configured to obtain a measurement of a parameter associated with a sample in the zone of interest. The mobile testing and evaluation vehicle can further include a controller that is configured to receive the measurement, evaluate the sample based on the measurement, and evaluate the zone of interest based on evaluating the sample.
G05D 1/02 - Commande de la position ou du cap par référence à un système à deux dimensions
G01N 1/08 - Dispositifs pour prélever des échantillons à l'état solide, p.ex. par coupe à l'outil impliquant un outil d'extraction, p.ex. mèche cylindrique creuse ou trépan
A method, system, and computer program product for designing reconfigurable kinematic devices. An example aspect is configured to: model two rigid stages of the device, assign at least one degree of freedom to at least one kinematic mode of the device; design at least one flexural rod; place at least one tunable flexure; assign a thickness to the at least one flexural rod; add mechanical details; and modularize the device for printing. A kinematic device configured to provide haptic feedback or motion control having at least two rigid stages, at least one kinematic mode, at least one flexural rod, and at least one tunable flexure.
G06F 30/15 - Conception de véhicules, d’aéronefs ou d’embarcations
G06F 30/17 - Conception mécanique paramétrique ou variationnelle
G06F 30/12 - CAO géométrique caractérisée par des moyens d’entrée spécialement adaptés à la CAO, p.ex. interfaces utilisateur graphiques [UIG] spécialement adaptées à la CAO
G06F 30/20 - Optimisation, vérification ou simulation de l’objet conçu
31.
SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR GENERATING MODIFIED LIGHT EMISSIONS
Provided are systems, methods, and computer program products for generating modified light emissions. The system includes at least one signal receiver arranged on a vehicle, at least one sensor arranged on the vehicle, at least one lighting system arranged on the vehicle, and at least one processor in communication with the at least one signal receiver, the at least one sensor, and the at least one lighting system, the at least one processor configured to: receive a first signal with the at least one signal receiver; receive sensor data from the at least one sensor; determine lighting data based on the first signal; generate a modified light emission by geometrically transforming the lighting pattern based on the sensor data; and control the at least one lighting system to output the modified light emission.
B60Q 1/14 - Agencement des dispositifs de signalisation optique ou d'éclairage, leur montage, leur support ou les circuits à cet effet les dispositifs étant principalement destinés à éclairer la route en avant du véhicule ou d'autres zones de la route ou des environs les dispositifs étant des phares comportant un dispositif d'atténuation de la lumière
B60Q 1/46 - Agencement des dispositifs de signalisation optique ou d'éclairage, leur montage, leur support ou les circuits à cet effet les dispositifs ayant principalement pour objet d'indiquer le contour du véhicule ou de certaines de ses parties, ou pour engendrer des signaux au bénéfice d'autres véhicules pour engendrer des signaux à éclats durant la marche, autres que pour signaler le changement de direction, p.ex. appels de phares
B60R 11/04 - Montage des caméras pour fonctionner pendant la marche; Disposition de leur commande par rapport au véhicule
32.
MEDICAL PATCH FOR CONTROLLED DELIVERY OF WOUND HEALING FACTORS AND THERAPIES
The present disclosure is directed a medical device applied as patch to a wound to promote healing. Engineered cells are disposed in the device that can secrete wound healing factors in response to light utilizing optogenetics. Biomaterials can be formed as needles into which cells can be loaded. Biosensors can also be included to facilitate multi-point mapping of the wound healing process. Another feature is an electrical stimulator to enhance cell proliferation and differentiation, further enhancing wound repair.
A61M 37/00 - Autres appareils pour introduire des agents dans le corps; Percutanisation, c. à d. introduction de médicaments dans le corps par diffusion à travers la peau
Stretchable and flexible thermoelectric devices may generally include a substrate having an array of semiconductors in electrical communication via a plurality of liquid metal interconnects, and coated on at least a portion thereof with opposing liquid crystal elastomer layers. The liquid crystal elastomer layers may be reaction products of a reaction mixture of a mesogenic group, a spacer, a crosslinker, and a photoinitiator. The liquid crystal elastomer layers may alternately heat and cool to achieve cyclical bending actuation when voltage is applied to the thermoelectric device. Methods of making and using the thermoelectric devices are also described.
H10N 10/856 - Matériaux actifs thermoélectriques comprenant des compositions organiques
H10N 10/13 - Dispositifs thermoélectriques comportant une jonction de matériaux différents, c. à d. dispositifs présentant l'effet Seebeck ou l'effet Peltier fonctionnant exclusivement par les effets Peltier ou Seebeck caractérisés par les moyens d'échange de chaleur à la jonction
F03G 7/06 - Mécanismes produisant une puissance mécanique, non prévus ailleurs ou utilisant une source d'énergie non prévue ailleurs utilisant la dilatation ou la contraction des corps produites par le chauffage, le refroidissement, l'humidification, le séchage ou par des phénomènes similaires
H01L 25/00 - Ensembles consistant en une pluralité de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide
Methods of controlling a computing system based on wiggling and/or other types of continuous multidirectional gesturing. In some embodiments, the methods monitor user gesturing for the occurrence of a recognizable item-action gesture that a user has made without having provided any other input to the computing system and then take one or more actions in response to recognizing the item-action gesture. In some embodiments, the actions include identifying one or more on-display item underlying the item-action gesture, duplicating the identified item(s) to one or more target locations, and adding one or more visual indicia to the identified on-display item(s), among other things. In some embodiments, a user can append an item-action gesture with one or more action extensions that each cause the computing system to take one or more additional actions concerning the identified on-display item(s). Software for performing one or more of the disclosed methodologies is also disclosed.
G06F 3/0488 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] utilisant des caractéristiques spécifiques fournies par le périphérique d’entrée, p.ex. des fonctions commandées par la rotation d’une souris à deux capteurs, ou par la nature du périphérique d’entrée, p.ex. des gestes en fonction de la pression exer utilisant un écran tactile ou une tablette numérique, p.ex. entrée de commandes par des tracés gestuels
G06F 3/0484 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p.ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs
G06F 3/14 - Sortie numérique vers un dispositif de visualisation
35.
SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR OPTICAL VIBRATION SENSING
Provided are systems, methods, and computer program products for optical vibration sensing. The system includes a first visual sensor, a second visual sensor, and at least one processor in communication with the first visual sensor and the second visual sensor, the at least one processor configured to: capture at least one first image comprising at least one light on at least one object with the first visual sensor, capture at least one second image comprising the at least one light on the at least one object with the second visual sensor, and determine a vibration of the at least one object based on the at least one light captured in the at least one first image and the at least one second image.
G01H 9/00 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores en utilisant des moyens sensibles aux radiations, p.ex. des moyens optiques
Provided herein are methods, nucleic acids, transformed yeast cells, and kits useful for rapid and effective multiplexed identification of nanobody binding to a target protein domain.
C40B 30/04 - Procédés de criblage des bibliothèques en mesurant l'aptitude spécifique à se lier à une molécule cible, p.ex. liaison anticorps-antigène, liaison récepteur-ligand
G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
Provided herein is a method of detecting or quantifying a microbe, such as a virion or bacteria cell, in a biological sample by agglutination with a yeast cell expressing on its surface a fusion protein including an anchor, a nanobody peptide, and a fluorogen-activating peptide. Also provided herein are yeast cells comprising a gene for expressing the fusion protein and a kit comprising the yeast cells.
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet
C12Q 1/6804 - Analyse d’acides nucléiques utilisant des immunogènes
Disclosed herein is a system and method for generating complex, concave polygonal bonding boxes which tightly cover the most representative faces of retail products having arbitrary poses. The polygonal bounding boxes do not include unnecessary background information or miss parts of the objects, as would the axis-aligned or rotated bounding boxes produced by prior art detectors. A simple projection transformation can correct the pose of products for downstream tasks.
G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p.ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersections; Analyse de connectivité, p.ex. de composantes connectées
39.
3D-PRINTED MICRO-SUPERCAPACITORS AND METHODS FOR FABRICATING THE SAME
Three-dimensional micro-supercapacitors and methods for fabrication of micro- supercapacitors are provided. A micro-supercapacitor embodiment includes a three- dimensional electrode with self-supporting layers of two-dimensional nanomaterial. A method embodiment includes using non-contact 3D printing to generate a micro- supercapacitor, including a three-dimensional electrode having self-supporting two- dimensional nanomaterial.
H01G 11/24 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrodes caractérisées par les propriétés structurelles des poudres ou particules utilisées à cet effet
H01G 11/26 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrodes caractérisées par leur structure, p.ex. multicouches, selon la porosité ou les caractéristiques de surface
H01G 11/36 - Nanostructures, p.ex. nanofibres, nanotubes ou fullerènes
B33Y 80/00 - Produits obtenus par fabrication additive
H01G 11/84 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants
H01G 11/86 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants spécialement adaptés pour les électrodes
Systems, apparatuses and methods for automated perineal care are provided. A system embodiment includes a user support element, a sensor configured to measure a cleanliness state of a user, a cleaning element configured to clean a user perineal area, and a controller configured to command operation of the cleaning element based on the sensor. An apparatus embodiment includes a containment structure, a sensor, a cleaning element assembly including a drive, actuator and a nozzle, and a controller configured to control the cleaning element assembly based on the sensor. A method embodiment includes positioning a user into a perineal cleaning position, scanning the user with a sensor, determining a cleanliness status, and activating a cleaning element based on the cleanliness status.
A system, method, and computer program product for predicting properties of electrolytes in a liquid electrolyte mixture independent of empirical fitting from experimentally measured properties. An example aspect is configured to: validate at least one molecular force field, prepare a liquid electrolyte mixture corresponding to the at least one molecular force field, perform molecular dynamic simulations of the electrolyte mixture, obtain simulated molecular dynamic trajectories from the molecular dynamic simulations, and perform molecular structure analysis to predict ionic conductivity, ion pairing properties, solubility properties, and/or other thermodynamic properties of the liquid electrolyte mixture.
G16C 10/00 - Chimie théorique computationnelle, c. à d. TIC spécialement adaptées aux aspects théoriques de la chimie quantique, de la mécanique moléculaire, de la dynamique moléculaire ou similaires
G16C 60/00 - Science informatique des matériaux, c. à d. TIC spécialement adaptées à la recherche des propriétés physiques ou chimiques de matériaux ou de phénomènes associés à leur conception, synthèse, traitement, caractérisation ou utilisation
G06F 3/00 - Dispositions d'entrée pour le transfert de données destinées à être traitées sous une forme maniable par le calculateur; Dispositions de sortie pour le transfert de données de l'unité de traitement à l'unité de sortie, p.ex. dispositions d'interface
42.
SYSTEMS AND METHODS FOR VERIFYING TRAIN CONTROLLERS
Disclosed herein is a system and method for formally verifying the safety of the Federal Railroad Administration freight train kinematics model with all its relevant forces and parameters, including track slope and curvature, airbrake propagation, and resistive forces as computed by the Davis equation.
G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p.ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
G06F 11/14 - Détection ou correction d'erreur dans les données par redondance dans les opérations, p.ex. en utilisant différentes séquences d'opérations aboutissant au même résultat
B61C 17/12 - Organes de commande; Dispositions pour la commande des locomotives à partir de points éloignés à bord du train ou lorsque des éléments de traction multiples sont utilisés
G06F 11/34 - Enregistrement ou évaluation statistique de l'activité du calculateur, p.ex. des interruptions ou des opérations d'entrée–sortie
43.
INTERACTIVE SYSTEM USING SPEECH RECOGNITION AND DIGITAL MEDIA
A system for interactive system using speech recognition and digital media is described. The system uses automated speech recognition and recognizes interactions from users to execute digital media items. The interactions are based on behavior of the user. The user is given a prompt. If the student responds to a prompt correctly, the student is rewarded with an animation. Otherwise the user experience continues without a reward. The system recognizes natural language responses for interactions of the user. The media item is dynamically generated as the user interacts with the digital media item.
The present disclosure is directed to simple, scalable methods of forming colloidal MXene dispersions in nonpolar organic solvents with long term stability.
A hybrid graphene material includes a functional group to expand the use of graphene in various applications. The hybrid material may include a substrate, such as silicon nanowires, where the graphene is fabricated on the surface of the substrate with an out-of-plane topography. Functional groups can be added to the graphene and affect the electrical, chemical, or photo characteristics of the hybrid material.
Provided herein are engineered lipid-bound vesicles for cytosolic delivery of an exogenous secreted, cell surface receptor-binding signaling molecule. Also provided herein are methods of making and using the engineered lipid-bound vesicles, and devices comprising the lipid-bound vesicles.
A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p.ex. rachitisme, maladie de Paget
B22F 12/00 - Appareils ou dispositifs spécialement adaptés à la fabrication additive; Moyens auxiliaires pour la fabrication additive; Combinaisons d’appareils ou de dispositifs pour la fabrication additive avec d’autres appareils ou dispositifs de traitement ou de fabrication
B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p.ex. génie protéique ou administration de médicaments
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
47.
SYSTEM AND METHOD FOR MATERIAL MODELLING AND DESIGN USING DIFFERENTIABLE MODELS
Disclosed herein is a framework for the modeling and design of materials based on differentiable programming, where the models can be trained by gradient-based optimization. Within this framework, all the components are differentiable and can be seamlessly integrated and unified with deep learning. The framework can design and optimize materials for a variety of applications.
G16C 60/00 - Science informatique des matériaux, c. à d. TIC spécialement adaptées à la recherche des propriétés physiques ou chimiques de matériaux ou de phénomènes associés à leur conception, synthèse, traitement, caractérisation ou utilisation
G16C 20/30 - Prévision des propriétés des composés, des compositions ou des mélanges chimiques
G16C 20/70 - Apprentissage automatique, exploration de données ou chimiométrie
G06N 7/00 - Agencements informatiques fondés sur des modèles mathématiques spécifiques
48.
FREEFORM FABRICATION OF THREE-DIMENSIONAL STRUCTURES USING A DROPLET-ON-DEMAND PROCESS WITH CONTINUOUS AND FREQUENCY MODULATED MATERIAL DEPOSITION
A method of forming a three-dimensional structure using droplet-based freeform printing is provided. The method includes depositing a structural material through one or more nozzles onto a surface of a substrate by droplet-based freeform printing, such as inkjet printing, to form one or more three-dimensional structures comprising a smooth surface and one or more cross-sectional dimensions. The structural material undergoes a liquid-to-solid transition after deposition of the structural material, and the one or more cross-sectional dimensions are controlled by a droplet ejection frequency. A method of fabricating a matrix including a three-dimensional structure including forming a negative three-dimensional template using droplet-based freeform printing, depositing, such as casting, a matrix material over the negative three-dimensional template and at least a portion of the surface of the substrate and solidifying the matrix material to form a matrix comprising the one or more three-dimensional structures of the negative template is also provided.
B29C 33/52 - Moules ou noyaux; Leurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p.ex. des objets à contre-dépouille solubles ou fusibles
B29C 39/02 - Moulage par coulée, c. à d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulage; Appareils à cet effet pour la fabrication d'objets de longueur définie, c. à d. d'objets séparés
B33Y 80/00 - Produits obtenus par fabrication additive
Disclosed herein is a method for defining a model of a trusted loT security gateway architecture based on a microhypervisor, wherein evaluation of the model provides a guarantee that the correct security protections are applied to each loT device's network traffic at all times, including when under attack. The models defined in accordance with the method disclosed herein are used to verify security gateway architectures that provide robust trust properties to a broad range of legacy hardware platforms utilizing existing software with a reasonable performance overhead.
G06F 9/455 - Dispositions pour exécuter des programmes spécifiques Émulation; Interprétation; Simulation de logiciel, p.ex. virtualisation ou émulation des moteurs d’exécution d’applications ou de systèmes d’exploitation
G06F 9/50 - Allocation de ressources, p.ex. de l'unité centrale de traitement [UCT]
H04L 67/10 - Protocoles dans lesquels une application est distribuée parmi les nœuds du réseau
Disclosed herein is a system and method for the automatic detection of persons engaged in the open carry of firearms at a venue. The system and method comprise strategically placed cameras at the venue which are connected to edge devices which extract frames from video generated by the cameras. The video frames are sent to a server for analysis by an AI/ML model trained to detect firearms and, specifically, to detect persons carrying firearms. If a person wielding a firearm is detected in any image, an alert is raised and local authorities are automatically contacted. The system is designed to run continuously such as to be able to quickly detect a person in a venue carrying a firearm.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
A tactile interaction device uses a plurality of shape-changing tactile elements that are driven by electro-osmotic flow of a fluid. An electric filed applied to a pumping membrane by two electrodes is responsible for inducing a flow of the liquid. Multiple tactile elements can be used on the device to permit localized tactile feedback to a user. The device is adapted to be in contact with the user's skin, such as a finger or hand.
The present disclosure relates to structures and methods of use of textiles for protection, and more particularly, relates to single layer knitted structures that can be worn as garments to block mosquito bites. The knit structures of the present embodiments can include single layer structures having a unique geometric combination of yarn properties and textiles to block mosquito bites in a single, comfortable layer of fabric. The knit structures can include one or more controllable parameters that can be adjusted to increase and/or decrease the bite blocking ability of the knit structure.
A01M 29/34 - CAPTURE OU PIÉGEAGE DES ANIMAUX OU ÉPOUVANTAILS; APPAREILS DE DESTRUCTION D'ANIMAUX OU DE PLANTES NUISIBLES Épouvantails ou dispositifs répulsifs, p.ex. pour oiseaux empêchant l'accès ou obstruant le passage, p.ex. au moyen de barrières, de pics, de cordons, d'obstacles ou d'aspersion d'eau spécialement adaptés aux insectes
A01M 29/30 - CAPTURE OU PIÉGEAGE DES ANIMAUX OU ÉPOUVANTAILS; APPAREILS DE DESTRUCTION D'ANIMAUX OU DE PLANTES NUISIBLES Épouvantails ou dispositifs répulsifs, p.ex. pour oiseaux empêchant l'accès ou obstruant le passage, p.ex. au moyen de barrières, de pics, de cordons, d'obstacles ou d'aspersion d'eau
D04B 1/00 - Procédés de tricotage trame pour la production de tricots ou d'articles ne dépendant pas de l'emploi de machines spéciales; Tricots ou articles définis par de tels procédés
D04B 1/24 - Procédés de tricotage trame pour la production de tricots ou d'articles ne dépendant pas de l'emploi de machines spéciales; Tricots ou articles définis par de tels procédés spécialement conçus pour le tricotage d'articles de configuration particulière articles vestimentaires
D04B 1/14 - Autres tricots ou articles caractérisés principalement par l'emploi de matières spéciales pour le fil
53.
SCALABLE MANUFACTURING OF MICRONEEDLE ARRAYS USING AUTOMATED HIGH-THROUGHPUT MANUFACTURING SYSTEMS AND HIGH-CAPACITY MOLDING
A manufacturing method for making a plurality of microneedle arrays (MNAs) includes: dispensing a polymer resin into a plurality of wells of at least one mold by an automated dispenser comprising at least one dispensing nozzle; centrifuging the at least one mold to distribute the dispensed polymer resin within the plurality of wells of the at least one mold; curing, solidifying, and/or drying the polymer resin within the plurality of wells of the at least one mold; and removing individual molded MNA parts from the at least one mold with at least one electromechanical mover controlled by at least one computer processor. A mold for making a plurality of the MNAs and a high-throughput manufacturing system for making the MNAs using the mold are also provided.
A61M 37/00 - Autres appareils pour introduire des agents dans le corps; Percutanisation, c. à d. introduction de médicaments dans le corps par diffusion à travers la peau
A61B 5/15 - Dispositifs de prélèvement d'échantillons de sang
A61M 5/32 - Seringues - Parties constitutives - Parties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchon; Accessoires pour introduire l'aiguille dans le corps ou l'y maintenir; Dispositifs pour la protection des aiguilles
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
54.
METHODS FOR ENGINEERING AND USE OF CILIATED ORGANOIDS HAVING NATIVE-LIKE, APICAL-OUT POLARITY
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
55.
SYSTEMS AND METHODS FOR PERSONALIZED ULTRASOUND NEUROMODULATION
Disclosed herein is a system and method for implementing a personalized ultrasound neuromodulation system and methods with neural sensing of personalized electrophysiological data, guiding ultrasound targeting and dosage using such personalized data. Specific ultrasound transducer solutions are provided for various neural targets that enable the low-intensity focused ultrasound to modulate the central nervous system and peripheral nervous systems to treat a variety of neurological and mental disorders. A portable ultrasound console device, a wearable guiding apparatus and a compact solution for effectively and safely enabling point-of-care neuromodulation, e.g., home healthcare, are provided. Further methods for ultrasound waveform customization are also described to improve effectiveness of ultrasound neuromodulation.
Disclosed herein is a system and method implementing a trusted loT security gateway architecture, based on a microhypervisor, that provides a guarantee that the correct security protections are applied to each loT device's network traffic at all times, including when under attack. The disclosed architecture provides robust trust properties to a broad range of legacy hardware platforms utilizing existing software with a reasonable performance overhead.
G06F 21/57 - Certification ou préservation de plates-formes informatiques fiables, p.ex. démarrages ou arrêts sécurisés, suivis de version, contrôles de logiciel système, mises à jour sécurisées ou évaluation de vulnérabilité
G06F 21/71 - Protection de composants spécifiques internes ou périphériques, où la protection d'un composant mène à la protection de tout le calculateur pour assurer la sécurité du calcul ou du traitement de l’information
H04W 84/18 - Réseaux auto-organisés, p.ex. réseaux ad hoc ou réseaux de détection
57.
METHODS FOR FABRICATING AIRWAY ORGANOIDS WITH NATIVE-LIKE, APICAL-OUT POLARITY
A method of fabricating an apical-out airway organoid is accomplished by using a culture medium substantially free of an extracellular matrix material. Mature apical-out airway organoids containing exterior-facing cilia can be induced into rotation when surrounded by a matrix material, such as Matrigel®. A process for quantifying the apical-out airway organoid rotation can be used to measure cilia motility.
G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
58.
LIPID NANOPARTICLE FORMULATIONS FOR GASTROINTESTINAL DELIVERY
Lipid-containing particles and drug products containing the lipid-containing particles are provided. Methods of local and systemic delivery of therapeutic agents to, and through, mucosa, such as intestinal mucosa, are provided.
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
A61K 47/10 - Alcools; Phénols; Leurs sels, p.ex. glycérol; Polyéthylène glycols [PEG]; Poloxamères; Alkyléthers de PEG/POE
C08G 65/332 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant de l'oxygène contenant des groupes carboxyle, ou leurs halogénures ou esters
59.
SYSTEM AND METHOD IMPLEMENTING A BATTERY AVIONICS SYSTEM FOR ELECTRIC-POWERED AIRCRAFT
Disclosed herein is a system and method implementing a battery avionics system for integrating battery monitoring, control, and management functions with an avionics system of an aircraft. The system uses a model implementing a battery pack digital twin, which is a continuous simulation of the operation of the battery pack within the aircraft, receives data regarding the battery pack generated by the digital twin model and provides optimized parameters to the battery avionics system. The system enables high precision, cell-level resolution control of the battery pack. The system estimates the state of charge, state of health, state of safety, and state of function of the cells and the battery pack as a whole and uses this information to manage the battery pack, given a particular flight profile of the aircraft.
B64D 27/24 - Aéronefs caractérisés par le type ou la position des groupes moteurs utilisant la vapeur, l'électricité ou l'énergie de ressorts
B60L 58/21 - Procédés ou agencements de circuits pour surveiller ou commander des batteries ou des piles à combustible, spécialement adaptés pour des véhicules électriques pour la surveillance et la commande des batteries de plusieurs modules de batterie ayant la même tension nominale
60.
DIRECT DRIVE END-EFFECTORS WITH PARALLEL KINEMATICS
A gripper includes at least one movable finger. Each movable finger includes a first motor, a second motor, a first motor link having a first end coupled to a rotor of the first motor, a second motor link having a first end coupled to a rotor of the second motor, a finger link having a first end in pivotal connection with a second end of the second motor link and a gripper pad, and a connecting link having a first end in pivotal connection with a second end of the first motor link and a second end in pivotal connection with the finger link. The gripper further includes at least one controller programmed or configured to actuate the first motor and the second motor of each of the at least one movable finger.
invitro in vivo in vivo. Extracellular matrix materials, such as collagen, are functionalized with chemicals that are complimentary to ligands disposed on the surface of the extracellular vesicle. In one example embodiment, collagen is functionalized with dibenzocyclooctyne and the extracellular vesicle is functionalized with an azide tag. The extracellular vesicle is immobilized within the collagen through a click reaction involving the dibenzocyclooctyne and the azide tag.
Disclosed herein is a system and method for selecting a battery for a particular application, for example, batteries used in portable electronics, electric vehicles, satellites, etc. The method uses an end-to-end differentiable modeling approach that allows the selection of batteries directly from the parameters of the battery and a specification of the particular application for which the batteries are being selected.
G01R 31/36 - Dispositions pour le test, la mesure ou la surveillance de l’état électrique d’accumulateurs ou de batteries, p.ex. de la capacité ou de l’état de charge
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
63.
SYSTEM AND METHOD FOR DEEP LEARNING FOR TRACKING CORTICAL SPREADING DEPRESSION USING EEG
Disclosed herein is a system and method implementing an automated, generalizable model for tracking cortical spreading depressions using EEG. The model comprises convolutional neural networks and graph neural networks to leverage both the spatial and the temporal properties of CSDs in the detection. The trained model is generalizable to different head models such that it can be applied to new patients without re-training. Further, the model is scalable to different densities of EEG electrodes, even when trained on a specific electride density.
Lipid-containing particles and formulations containing the lipid-containing particles are provided. Methods of delivery of therapeutic agents to the pancreas using the lipid-containing particles are provided.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiques; Thérapie génique
65.
SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR EXTRACTING FEATURES FROM IMAGING BIOMARKERS WITH MACHINE-LEARNING MODELS
Provided are systems, methods, and computer program products for extracting features from imaging biomarkers with machine-learning models. The method includes training a first artificial intelligence (AI) model based on first training data including images labeled with imaging biomarkers, the first AI model trained to identify a plurality of imaging biomarker features in at least one image, training a second AI model based on second training data including sets of imaging biomarker features associated with task-specific labels, the second AI model trained to identify at least one task-specific feature based at least partially on a set of imaging biomarker features, processing at least one input image with the first AI model to generate a first AI model output, and processing the first AI model output with the second AI model to generate a second AI model output.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
Methods for assisting one or more users in organizing content-items, such as location information (e.g., URLs) for online information resources (e.g., webpages) and clips taken from information resources, accessed via content-access software, such as one or more web browsers, using a content item-bundle primitive that allows users to create, build, manipulate, and/or populate their own content-item bundles according to their information investigation and collection desires/needs. In some embodiments, the methods include automatically bundling content items into suggested content-item bundles based on learned relationships among various content items. In some embodiments, the methods can be implemented to provide bundle-based task managers that allow users to not only organize their content items but also define tasks and/or projects rooted in the content-item-bundle primitive. Further embodiments are disclosed, as is software for executing disclosed methods.
G06F 16/955 - Recherche dans le Web utilisant des identifiants d’information, p.ex. des localisateurs uniformisés de ressources [uniform resource locators - URL]
A method and apparatus for degrading a hypodermal tissue scaffold involves exposing the scaffold to a low-intensity focused ultrasonic beam such as to burst gas vesicles trapped in the silk fibroin from which scaffold is constructed. The rate of degradation van be controlled using ultrasonic beams of varying intensities. In one embodiment, the ultrasonic beams are administered trans-dermally to a hypodermal scaffold.
A61K 47/42 - Protéines; Polypeptides; Leurs produits de dégradation; Leurs dérivés p.ex. albumine, gélatine ou zéine
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
C07K 16/22 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des facteurs de croissance
A61L 27/60 - Matériaux utilisables pour la peau artificielle
Disclosed herein is a system providing a mixed reality combination system that pairs augmented reality technology and an inertial measurement unit sensor with 3D printed objects such that user motions tracked by the inertial measurement unit as the user interacts with the 3D printed object is reflected in a virtual environment display of dynamic 3D imagery and augmented reality imagery.
Disclosed herein is a system and method for augmenting data by generating a plurality of pose-altered images of an item from one or more 2D images of the item and using the augmented data to train a train a feature extractor. In other aspects of the invention, the trained feature extractor is used to enroll features extracted from images of new products in a library database of known products or to identify images of unknown products by matching features of an image of the unknown product with features stored in the library database.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
G06K 9/46 - Extraction d'éléments ou de caractéristiques de l'image
A method of manufacturing a porous part includes controlled freeze casting of a slurry. After freezing, a solvent in the slurry is removed by sublimation and the remaining material is sintered to form the porous part. Spatial and temporal control of thermal conditions at the boundary and inside of the mold can be controlled to create parts with controlled porosity, including size, distribution, and directionality of the pores. Porous parts with near-net-shape from ceramics, metals, polymers and other materials and their combinations can be created.
B22F 1/107 - Poudres métalliques contenant des agents lubrifiants ou liants; Poudres métalliques contenant des matières organiques contenant des matériaux organiques comportant des solvants, p.ex. pour la coulée en moule poreux ou absorbant
B22F 3/00 - Fabrication de pièces ou d'objets à partir de poudres métalliques, caractérisée par le mode de compactage ou de frittage; Appareils spécialement adaptés à cet effet
B22F 3/22 - Fabrication de pièces ou d'objets à partir de poudres métalliques, caractérisée par le mode de compactage ou de frittage; Appareils spécialement adaptés à cet effet pour la fabrication de pièces par coulée en moule poreux ou absorbant, c. à d. par coulée d'une suspension de poudre métallique dans un moule poreux, d'une façon analogue au coulage de la barbotine
B28B 1/00 - Fabrication d'objets façonnés à partir du matériau
B29C 39/00 - Moulage par coulée, c. à d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulage; Appareils à cet effet
Disclosed herein is a system and method for performing pose-correction on images containing objects within a scene, or the entire scene, to compensate for off- centered camera views. The system and method generates a more frontal view of the object or scene by applying planar homography by identifying corner endpoints of the object or the scene and repositioning the corner endpoints to provide a more frontal view. The pose-corrected scene may then be input to an object detector to determine a location of a bounding box of an object-of-interest which would be more accurate than a bounding box from the original off-centered image.
Disclosed herein is a system and method for generating quadrilateral bonding boxes which tightly cover the most representative faces of retail products having arbitrary poses. The quadrilateral boxes do not include unnecessary background information or miss parts of the objects, as would the axis-aligned bounding boxes produced by prior art detectors. A simple projection transformation can correct the pose of products for downstream tasks.
Disclosed herein is a system and method using an equivariant neural network for predicting quantum mechanical charge density. The equivariant neural network serves as a surrogate for the density-functional theory used to calculate a self- consistent field and predicts the central observable charge density, which, in addition to enabling force calculations, can also accelerate DFT itself and compute a full range of chemical properties.
Disclosed herein is a system and method for increasing the confidence of a match between the test image and an image stored in a library database. Features are extracted from the test image and compared to features stored in the image database and, if a match is determined, one or more transformations are performed on the test image to generate pose-altered images. Features are then extracted from the pose-altered images and matched with pose-altered images in the database. The scores for the subsequent matchings can be aggregated to determine an overall probability of a match between the test image in an image in the library database.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
G06K 9/46 - Extraction d'éléments ou de caractéristiques de l'image
G06K 9/64 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques utilisant des comparaisons ou corrélations simultanées de signaux images avec une pluralité de références, p.ex. matrice de résistances
75.
LASER-BASED FAST MICROMANUFACTURING OF TEST DEVICE FOR RAPID DETECTION OF PATHOGENS
A photonic crystal for detection of an analyte includes: a first layer including a first material with a first refractive index; a second layer over the first layer and including a second material with a second refractive index that is higher than the first refractive index; where the second layer includes a hole, the hole including: a first diameter from an outer surface of the second layer to a first hole depth; a second diameter from the first hole depth to a second hole depth; where the first diameter is larger than the second diameter; and a member of a binding pair with the analyte linked to a surface of the hole.
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c. à d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
G01N 21/25 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
G01N 21/31 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique
G01N 21/35 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge
76.
SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR SEGMENTING AN IMAGE
Provided are systems, methods, and computer program products for segmenting an image. A method includes segmenting each image in a sequence of images including a needle into a needle and at least one needle artifact based on processing each image with a first machine-learning model trained with a plurality of hard labels for a plurality of images, resulting in a plurality of hard-labeled images, transforming each hard-labeled image of the plurality of hard-labeled images into a soft-labeled image including pixel values corresponding to an effect of the at least one needle artifact, resulting in a plurality of soft-labeled images, and segmenting at least one image of the sequence of images based on processing the at least one image with a second machine-learning model trained at least partially with the plurality of soft-labeled images.
Provided are methods including the steps of receiving, with at least one computing device, an image of a portion of a subject, assigning; with the at least one computing device and based on a machine-learning model, a label to one or more pixels of the image to generate a diagnostically segmented image; and classifying, with the at least one computing device and based on a machine-learning model, the diagnostically segmented image and the one or more pixels into at least one class to generate a classified image, wherein the classified image includes a classification label indicating a clinical assessment of the portion of the subject and wherein the one or more pixels include a clinical label indicating a diagnosis of a portion of a subject contained within each pixel, based on the diagnostically segmented image having labels assigned to each pixel of the segmented image.
Provided is a system, method, and computer program product for training a machine-learning model. The method includes labeling each object of a plurality of objects with a probabilistic confidence label including a probability classification score for each class of at least two classes, resulting in a plurality of probabilistic confidence labels associated with the plurality of objects, and training, with at least one computing device, the machine-learning model based on the plurality of objects and the plurality of probabilistic confidence labels.
Provided is a system, method, and computer program product for tracking a needle. The method includes determining a visibility of the needle being inserted into a subject in an image of a sequence of images, in response to determining that the visibility satisfies a visibility threshold, detecting a location of the needle based on at least one first algorithm and a detected curvature of the needle, in response to determining that the visibility does not satisfy the visibility threshold, detecting the location of the needle being inserted based on at least one second algorithm, and tracking the location of the needle in the sequence of images based on locations detected with the at least one first algorithm and the at least one second algorithm.
Provided is a system, method, and computer program product for determining a needle injection site. The method includes segmenting, with at least one computing device, an image of a sequence of images into at least one object based on a machine-learning model configured to estimate its uncertainty for each segmentation, generating, with the at least one computing device, a 3D model of the at least one object, and determining, with the at least one computing device, an insertion location of the at least one object based at least partially on an output of the machine-learning model.
A61K 38/00 - Préparations médicinales contenant des peptides
C07H 21/00 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques
C07K 14/00 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés
82.
SYSTEM, METHOD, AND APPARATUS FOR SENSOR DRIFT COMPENSATION
A system includes an inertial sensing device having an inertial sensor and plurality of stress sensors configured to measure stress applied to the inertial sensing device, and at least one computing device configured to: receive sensor data from the inertial sensor and the plurality of stress sensors; and determine a drift compensation of the inertial sensor based on the sensor data. Other systems, methods, and devices are disclosed.
G08B 29/18 - Prévention ou correction d'erreurs de fonctionnement
B81B 7/02 - Systèmes à microstructure comportant des dispositifs électriques ou optiques distincts dont la fonction a une importance particulière, p.ex. systèmes micro-électromécaniques (SMEM, MEMS)
G01C 19/5776 - Traitement de signal non spécifique à l'un des dispositifs couverts par les groupes
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pression; Transmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
G01P 1/00 - MESURE DES VITESSES LINÉAIRES OU ANGULAIRES, DE L’ACCÉLÉRATION, DE LA DÉCÉLÉRATION OU DES CHOCS; INDICATION DE LA PRÉSENCE OU DE L’ABSENCE D’UN MOUVEMENT; INDICATION DE LA DIRECTION D’UN MOUVEMENT - Parties constitutives des instruments
G01P 15/02 - Mesure de l'accélération; Mesure de la décélération; Mesure des chocs, c. à d. d'une variation brusque de l'accélération en ayant recours aux forces d'inertie
83.
METHOD FOR COMPRESSING AN AI-BASED OBJECT DETECTION MODEL FOR DEPLOYMENT ON RESOURCE-LIMITED DEVICES
Disclosed herein is a method for efficiently reducing the computational footprint of any AI-based object detection model, so as to enable its real-time deployment on computing resource-limited (i.e., low-power, embedded) devices. The disclosed method provides a step-by-step framework using an optimized combination of compression techniques to effectively compress any given AI-based object detection model.
G06V 10/40 - Extraction de caractéristiques d’images ou de vidéos
G06V 10/77 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 10/80 - Fusion, c. à d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (USA)
Inventeur(s)
Galeotti, John, Michael
Stetten, George, Dewitt
Huang, Chun-Yin
Abrégé
Provided is a system, method, and computer program product for tracking an object based on skin images. A method includes capturing, with at least one computing device, a sequence of images with a stationary or movable camera unit arranged in a room, the sequence of images including the subject and an object moving relative to the subject, and determining, with at least one computing device, the pose of the object with respect to the subject in at least one image of the sequence of images based on computing or using a prior surface model of the subject, a surface model of the object, and an optical model of the stationary or movable camera unit.
Disclosed herein is a system and method for pooling local features for fine-grained image classification. The deep features learned by the deep network are augmented with low level local landmark features by learning a pooling strategy that pools landmark features from earlier layers of the deep network. These low level landmark features are combined with the deep features and sent to the classifier.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
Disclosed herein is a system and method for novel neural architecture search using a random graph network backbone to facilitate the creation of an efficient network structure. The method utilizes reinforcement learning algorithms to build a complex relationship between intra-connections (i.e., links between blocks in a random graph network) and extra-connections (i.e., links among blocks across the random graphs network) for discovering an efficient random neural architecture.
Provided is a method for locating an epilepsy seizure onset zone and prediction of seizure outcome including receiving interictal electroencephalographs from two or more points in a patient's cerebral cortex. The interictal electroencephalographs are used to determine directional information flow values which indicate dominant information flow from a non-seizure zone to a seizure onset zone. The directional informational flow values may be input into a classification model trained to predict whether the two or more points in the patient's cerebral cortex are a seizure onset zone and/or classify the patient's predicted post-treatment seizure outcome after epilepsy treatment based on the directional information flow values. An output from the classification model may indicate a location of seizure onset zone in the patient's cerebral cortex and/or the patient's predicted post-treatment seizure outcome after epilepsy treatment. Systems and computer program products are also provided.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/291 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électroencéphalographie [EEG]
A61B 5/369 - Modalités, c. à d. méthodes diagnostiques spécifiques Électroencéphalographie [EEG]
A61B 5/374 - Détection de la répartition de fréquence dans les signaux, p.ex. détection des ondes delta, thêta, alpha, bêta ou gamma
88.
SYSTEM AND METHOD FOR REDUCING FALSE POSITIVES IN OBJECT DETECTION FRAMEWORKS
Disclosed herein is a system and method for reducing false positives in object detection frameworks. A human form view of objects detected by the object detection framework and indicates the object is a false positive. When an indication of a false positive been received, a feature representation of displayed object stored in the gallery. During an inference or testing phase, the gallery is searched for a feature representation matching the feature representation of the detected objects, and, if a match is found, the detected object is deemed to be a false positive and is not displayed to the user.
Disclosed herein is a system and method for evolving a deep neural network model by searching for hidden sub-networks within the model. The model is evolved by adding convolutional layers to the model, then pruning the model to remove redundant filters. The model is exposed to training samples of increasing complexity each time the model is evolved, until a desired level of performance is achieved, at which time, the model is exposed to all available training data.
Disclosed herein is an improved method for identifying images containing objects-of-interest from a large set of images. The method comprises mixing two or more of the images to create a grouped image and exposing the grouped image to an object detector trained on grouped images to make an initial determination that the grouped image was formed from at least one image containing an object-of-interest. The images which formed the grouped image are then exposed to regular object detectors to determine a classification of the object-of-interest.
Disclosed herein is an improved few-shot detector which utilizes a dynamic semantic network which takes as input a language feature and generates trainable parameters for a visual network. The visual network takes a visual feature as input and generates a classification and localization of an object.
Disclosed herein is a methodology for refining novel-class features in a few-shot learning scenario by fine-tuning the feature extractor by reducing both class-agnostic biases and class-specific biases. A distribution calibration module is used to reduce the class-agnostic bias by normalizing the overall feature distribution for novel classes and further reshaping the feature manifold for fast adaptation during fine-tuning. Selected sampling is used to reduce class-specific bias by augmenting more data for better estimation.
Disclosed herein an effective detach strategy which suppresses the flow of gradients from context sub-networks through the detection backbone path to obtain a more discriminative context by forcing the representation of context sub-network to be dissimilar from the detection network. A sub-network is defined to generate the context information from early layers of the detection backbone. Because instance and context focus on perceptually different parts of an image, the representations from either of them should also be discrepant. In addition, a stacked complementary loss is generated to and backpropagated to the detection network.
Disclosed herein is a methodology implementing feature map-level data augmentation in a feature map. Two or more units in the feature map are selected and the values of locations in the two or more units are swapped among the two or more units. Value perturbations applied around local units in the feature map implicitly lead to an unused data augmentation at the image level.
Disclosed herein is a method to disentangle linear-encoded facial semantics from facial images without external supervision. The method uses linear regression and sparse representation learning concepts to make the disentangled latent representations easily interpreted and manipulated. Generated facial images are decomposed into multiple semantic features and latent representations are extracted to capture interpretable facial semantics. The semantic features may be manipulated to synthesize photorealistic facial images by sampling along vectors representing the semantic features, thereby changing the associate semantics.
Disclosed herein is a system and method for data augmentation for general object recognition which preserves the class identity of the augmented data. The system comprises an image recognition network an image generation network that take as input ground truth images and classes respectively and which generates a predicted class and an augmented image. A discriminator evaluates the predicted class and augmented image and provides feedback to the image recognition network and the image generation network.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
Disclosed herein is a method of soft anchor-point detection (SAPD), which implements a concise, single-stage anchor-point detector with both faster speed and higher accuracy. Also disclosed is a novel training strategy with two softened optimization techniques: soft-weighted anchor points and soft-selected pyramid levels.
Disclosed herein is a method providing a flexible way to transfer knowledge from base to novel classes in a few shot learning scenario. The invention introduces a partial transfer paradigm for the few-shot classification task in which a model is first trained on the base classes. Then, instead of transferring the learned representation by freezing the whole backbone network, an efficient evolutionary search method is used to automatically determine which layer or layers need to be frozen and which will be fine-tuned on the support set of the novel class.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
Disclosed herein is a method of reducing the complexity of a neural network using PRC-NPTN layers by applying a pruning technique to remove a subset of filters in the network based on the importance of individual filters to the accuracy of the network, which is determined by the frequency with which the response of the filter is activated.
Disclosed herein is a design for a 1-bit CNN that closes the performance gap between binary neural networks and real-valued networks on challenging large-scale datasets. The design starts with a high-performance baseline network. Blocks with identity shortcuts which bypass 1-bit generic convolutions are adopted to replace the convolutions in the baseline network. Reshaping and shifting of activation functions is introduced. Finally, a distributional loss to further is adopted enforce the binary network to learn similar output distributions as those of a real-valued network.