The present disclosure relates to a continuous glucose monitoring device, in which a body attachment unit is manufactured so as to be assembled in an applicator, thereby minimizing additional work for a user in attaching the body attachment unit to a body, and allowing attachment of the body attachment unit to the body simply by operation of the applicator. In particular, a wireless communication chip is provided in the body attachment unit to enable communication with an external terminal, thereby enabling simple and convenient use without additional work of connecting a separate transmitter, and allowing easier maintenance. In addition, the continuous glucose monitoring device is activated by a user's operation after the body attachment unit is attached to the body, such that an activation start time can be adjusted to a time appropriate to the user's needs, and the continuous glucose monitoring device can be activated in a stabilized state, and thereby can monitor blood glucose more accurately.
The present invention relates to a continuous blood glucose measurement apparatus which, by manufacturing a body-attachable unit in an assembled state inside an applicator, minimizes the additional work by a user for attaching the body-attachable unit to the body and thus enables the body-attachable unit to be attached to the body simply by means of operating the applicator, and, by providing a wireless communication chip on the body-attachable unit and enabling communication with an external terminal, can be used in a simple and convenient manner without the additional work of connecting a separate transmitter and enables easier maintenance and management, and, by having the operation of the body-attachable unit initiated by means of the user's manipulation after being attached to the body, enables the operation initiation point to be adjusted to an appropriate point as necessary by the user, enables an operation initiation in a stabilized state and thus enables more accurate blood glucose measurement.
The present invention relates to a method for generating an alarm pertaining to continuous biometric data and, more specifically, to an alarm generation method in which, if an alarm condition is satisfied, an alarm is output to a user while maintaining the alarm in an activated state during a set alarm period, and changing the alarm type selected by the user during the alarm period, thereby enabling the user to be prompted to input information or take an action in response to the alarm without ignoring the alarm, while not causing inconvenience to the user due to frequent alarms; and when the alarm condition is satisfied, an operating mode of a receiver is determined and the alarm type, which has been set in accordance with the alarm condition, is changed to an alarm type corresponding to the operating mode of the receiver, thereby making it possible to prevent an alarm from being generated against the user's wishes.
SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (Republic of Korea)
Inventor
Shin, Hyunseo
Moon, Bongjin
Kwon, Hoejun
Abstract
The present invention relates to a polypentafluorophenyl ester-based polymer used in the manufacturing of an electrochemical sensor, wherein the polymer has high reactivity with an amine functional group, causes less hydrolysis, retains good solubility, for general purposes, in organic solvents, and has low steric hindrance and toxicity or side effects compared with polymers having a similar structure, and thus is useful in an insertion-type device, especially a continuous glucose monitoring system, a part of which is inserted into the human body.
The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present invention relates to a body-attachable device attached to the body to continuously measure biometric data and, more particularly, to a body-attachable device capable of: accurately providing an alarm to a user by deciding upon an alarm mode on the basis of the state of communication establishment between a receiver and the body-attachable device and providing the alarm to the user; and protecting the health of the user or accurately measuring biometric data in an emergency by providing an alarm in an alarm mode which the user can promptly become aware of in accordance with the state of communication establishment with the receiver or the importance of the alarm.
The present invention relates to a method for generating an alarm pertaining to continuous biometric data and, more specifically, to an alarm generation method in which, if an alarm condition is satisfied, an alarm is output to a user while maintaining the alarm in an activated state during a set alarm period, and changing the alarm type selected by the user during the alarm period, thereby enabling the user to be prompted to input information or take an action in response to the alarm without ignoring the alarm, while not causing inconvenience to the user due to frequent alarms; and when the alarm condition is satisfied, an operating mode of a receiver is determined and the alarm type, which has been set in accordance with the alarm condition, is changed to an alarm type corresponding to the operating mode of the receiver, thereby making it possible to prevent an alarm from being generated against the user's wishes.
The present invention relates to a method for detecting a leakage current during use of a biometric data measuring device, and more particularly, a method is provided whereby it is possible to detect whether there is a leakage in a current applied to a sensor in a state of measuring biometric data while a part of the sensor is inserted into the user's skin, by comparing the difference in magnitude between an applied current applied via one terminal of the sensor, which is comprised in the biometric data measuring device, and an output current output via the other terminal of the sensor.
The present disclosure relates to a method for transmitting and receiving non-received biometric information, and more specifically, to a method for transmitting and receiving biometric information, wherein, when there is biometric information that a communication terminal has not received from a sensor transmitter, the reception of the non-received biometric information is controlled differently by determining, from received adjacent biometric information, whether the domain to which the non-received biometric information belongs is a dangerous domain or a normal domain.
The present disclosure relates to a biometric information management method based on location information of a user, and more specifically, to a biometric information management method in which a restaurant where a user is located is determined on the basis of location information of the user, and calorie intake of the user is determined on the basis of the calories of each food menu provided at the restaurant, and thus the calorie intake of the user may be accurately determined, and changes in biometric information may be accurately determined on the basis of the calorie intake.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
12.
METHOD FOR PROVIDING GUIDANCE ON USE PERIOD OF SENSOR
The present disclosure relates to a method for providing guidance on a use period of a sensor and, more specifically, to a method for providing guidance on a use period of a sensor, which accurately provides guidance to a user about a use period of a sensor by calculating the number of sensors possessed by the user and the total use period from the use period of each sensor so as to determine whether the remaining use period has arrived at an order guidance period or to determine whether the remaining use period of the last sensor has arrived at the order guidance period, on the basis of a sensor usage history of the user, and enable the user to order sensors on the basis of the guidance.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
13.
PIPETTE TIP AND PIPETTE SYSTEM FOR CAPILLARY BLOOD COLLECTION
The capillary blood pipette tip system of the present invention includes a pipette tip for collecting capillary blood including a sampling unit having a capillary tube having a first diameter so as to sample a capillary blood; a sample storage unit having a first extension end formed from a distal end of the capillary tube of the sampling unit so as to have a larger area than the sampling unit; a sealing unit closely adhered to a distal opening of the sample storage unit and broken by a quantitative syringe introduced from the outside; a shielding wall surrounding the sealing unit to prevent the sample from splashing from the sample storage unit to the outside when the sealing unit is broken by the quantitative syringe; and a handle unit which is held by a user to sample using the sampling unit; an immunoassay cartridge having at least one pipette tip mounting well having a plunger that presses a sample of a sampling unit of the pipette tip from the bottom to the top when the pipette tip is coupled to the top; and a quantitative syringe for quantitatively sampling the capillary blood collected in the upper part thereof by approaching through the upper part of the pipette tip, when the capillary blood from the sampling unit is collected in the upper part by the pressurization of the plunger during the coupling of the pipette tip to the immunoassay cartridge.
FUNCTIONALIZED THERMOPLASTIC POLYURETHANE, METHOD FOR PRODUCING SAME, METHOD FOR PRODUCING HIGHLY FUNCTIONAL MEDICAL COMPOSITE MATERIAL USING SAME, AND MEDICAL DEVICE INCLUDING SAME
The present invention pertains to: a functionalized thermoplastic polyurethane containing a novel chain extender having functionality capable of chemically bonding to a prepolymer polymerized by reacting a polyol (P) with a diisocyanate (R); a functional composite material containing one or more monomers or polymers selected from the group consisting of an anionic functional group, an amphoteric functional group, a perfluorinated compound, a hydrogel, and a silicone polymer; a method for producing same; and an article including same.
C08G 81/02 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
C07C 43/178 - Unsaturated ethers containing hydroxy or O-metal groups
C07C 323/12 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
C07C 217/08 - Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
15.
SENSOR APPLICATOR ASSEMBLY FOR CONTINUOUS GLUCOSE MONITORING SYSTEM
The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, Which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present disclosure relates to a body-attachable apparatus for measuring biometric information and, more particularly, to an apparatus for measuring biometric information, which can accurately measure biometric information by connecting an additional impedance to a sensor to reduce the magnitude of noise generated during deformation or movement of the sensor, and accurately measure the biometric information by removing noise affecting a response signal during the deformation or movement of the sensor, via the additional impedance.
SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (Republic of Korea)
Inventor
Shin, Hyunseo
Kang, Young Jea
Lee, Seok-Won
Moon, Bongjin
Kim, Gwang Jin
Abstract
The present invention relates: to a novel transition metal complex having a C—N ligand, which can be used for various devices including an electrochemical sensor, to a device comprising same; and preferably, to an electrochemical sensor.
The present disclosure relates to a method for transmitting or receiving biometric information between a sensor transmitter and a communication terminal in a continuous blood glucose measurement system and, more specifically, to a method for transmitting or receiving biometric information, wherein: it is not determined at every regular communication period whether biometric information has been successfully transmitted or received between a sensor transmitter and a communication terminal; it is determined whether unreceived biometric information exists only at a unreceived communication period relatively larger than the regular communication period; if unreceived biometric information exists, the unreceived biometric information is received; and it is accordingly possible to reduce computing loads required to determine at every regular communication period whether unreceived biometric information exists, and the waste of energy required to receive unreceived biometric information at every regular communication period.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
20.
NOVEL ORGANIC ELECTRON TRANSFER MEDIATOR AND DEVICE COMPRISING SAME
SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (Republic of Korea)
Inventor
Shin, Hyunseo
Kang, Young Jea
Lee, Seok-Won
Moon, Bongjin
Jeong, Myeonghwa
Yoon, Sangeun
Abstract
The present invention relates to a novel organic electron-transfer mediator showing an excellent oxidation-reduction potential and a device such as an electrochemical biosensor having improved performance comprising the same.
C07D 475/12 - Heterocyclic compounds containing pteridine ring systems containing pteridine ring systems condensed with carbocyclic rings or ring systems
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
21.
METHOD OF MANUFACTURING SENSOR TRANSMITTER FOR CONTINUOUS BLOOD GLUCOSE MEASUREMENT
The present disclosure relates to a manufacturing method for a sensor transmitter for continuous glucose monitoring and, more particularly, to a manufacturing method for a sensor transmitter, capable of generating quality control information in which production information of a sensor and production information of a transmitter that are used for the sensor transmitter during an assembly process of the sensor transmitter are mapped to each other, and storing and managing the generated quality control information in a server, so as to monitor a distribution channel or a sales channel of the sensor transmitter by using the quality control information, use for quality control of the sensor transmitter, or easily track a bad sensor transmitter.
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control (DNC), flexible manufacturing systems (FMS), integrated manufacturing systems (IMS), computer integrated manufacturing (CIM)
The present disclosure relates to a continuous glucose monitoring apparatus, and provides a continuous glucose monitoring apparatus of which a body-attachment unit starts operating, in a state in which the body-attachment unit is inside an applicator, by the supply of power to the body-attachment unit through a user operation, such as separation and removal of a protective cap, so that the operating start time point of the body-attachment unit is formed by means of the user operation immediately before the body-attachment unit is inserted into and attached to the human body, thereby enabling the body-attachment unit to start operating at an appropriate point in time, the body-attachment unit starts operating only by simply removing the protective cap even without performing separate additional work for starting operation of the body-attachment unit, thereby improving use convenience, and an operating method for a power supply switch means that supplies battery power to the body-attachment unit is formed as various methods that are linked with a separation and removal operation of the protective cap, and thus manufacturing and use convenience can be further improved.
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
METHOD FOR TRANSMITTING AND RECEIVING BIOMETRIC INFORMATION WITHOUT LOSS BASED ON TRANSMISSION PACKET IDENTIFIER IN CONTINUOUS BLOOD GLUCOSE MONITOR SYSTEM
The present disclosure relates to a method for transmitting/receiving biometric information in a continuous glucose monitoring system, and more specifically, to a method for transmitting/receiving biometric information, in which, in each communication cycle, first, an identifier of the last transmit packet received by a communication terminal is transmitted to a sensor transmitter, and the sensor transmitter transmits, to the communication terminal, a transmit packet generated after the last transmit packet, and thus biometric information generated by the sensor transmitter may be transmitted without loss to the communication terminal.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
H04L 1/16 - Arrangements for detecting or preventing errors in the information received by using return channel in which the return channel carries supervisory signals, e.g. repetition request signals
25.
SENSOR APPLICATOR ASSEMBLY FOR CONTINUOUS GLUCOSE MONITORING SYSTEM
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used disposables, thereby allowing accurate and safe use and convenient maintenance.
The present disclosure relates to a method for calculating the calibration sensitivity of a sensor for insertion into the body and, more particularly, to a method for calculating calibration sensitivity, wherein a biometric value of a user can be accurately calibrated by overcoming an error in a biometric value measured through a sensor for insertion into the body, or an error in a reference biometric value measured through a biometric information measurement device, by storing past sensitivities and using at least one of the past sensitivities and a currently calculated sensitivity to calculate a calibration sensitivity of the sensor for insertion into the body, and the calibration sensitivity of the sensor for insertion into the body can be accurately calculated, even if there is an error in the reference biometric value or the reference biometric value temporarily deviates from the range of normal biometric values of the user, by determining whether the reference biometric value used to calculate the calibration sensitivity is within an allowable range.
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present disclosure relates to a notification method of a continuous glucose monitoring system. A notification method of a continuous glucose monitoring system, according to one embodiment of the present invention, may comprise the steps of: performing a communication connection between a body attachment unit and a communication terminal for the communication terminal to receive blood glucose data measured from the body attachment unit which is attached to a human body and continuously measures blood glucose; transmitting information on the body attachment unit from the body attachment unit to the communication terminal and calculating a remaining use period of the body attachment unit; and generating, in the communication terminal, a notification on the remaining use period of the body attachment unit. According to the present disclosure, as the notification for the remaining period of the body attachment unit is generated in the communication terminal, there is an effect wherein a user can prepare in advance a body attachment unit to be replaced before the use period of the body attachment unit ends.
A paste for a reference electrode according to an embodiment of the present disclosure includes silver chloride powder and a carbon-based conductive material. The carbon-based conductive material may include at least one compound selected from the group consisting of carbon nanotubes, graphite, graphene, and carbon black. The reference electrode formed of the paste for a reference electrode according to an exemplary embodiment may provide improved mechanical properties and electrochemical properties.
H01B 1/22 - Conductive material dispersed in non-conductive organic material the conductive material comprising metals or alloys
A61B 5/259 - Means for maintaining electrode contact with the body using adhesive means, e.g. adhesive pads or tapes using conductive adhesive means, e.g. gels
G01N 27/30 - Electrodes, e.g. test electrodes; Half-cells
30.
METHOD FOR PROCESSING NOISE OF BIOMETRIC INFORMATION MEASUREMENT DATA
The present disclosure relates to a method for processing noise in biometric information measurement data, wherein the method for processing noise in biometric information measurement data, according to one embodiment of the present invention, may comprise the steps of: measuring biometric information by a sensor-transmitter which is placed on a part of a user's body and which measures biometric information of the user; transmitting data on the measured biometric information from the sensor-transmitter to a communication terminal; processing noise in the biometric information data transmitted to the communication terminal; and displaying the noise-processed biometric information data on the communication terminal. According to the present invention, it is possible to obtain accurate biometric information data by processing various types of noise included in biometric information data by using various algorithms to process steps for removing noise in a sequential manner.
The present disclosure relates to an insertion guide needle for a continuous glucose monitoring system. The insertion guide needle makes an incision in the skin by means of point-contact with the skin during a skin insertion process, and allows expanded incision of the skin continuously thereafter, thereby minimizing pain which may occur during the skin insertion process and thus relieving aversion or tension when the continuous glucose monitoring system is used. During a process of expanded incision of the skin, the insertion guide needle allows expanded incision continuously and gradually in the width direction and thickness direction, thereby reducing skin resistance during the expanded incision process and further reducing pain. In addition, during the expanded incision process, since the entire incision area is formed by an incision, the insertion guide needle is simply inserted along the incision area after a predetermined insertion section, such that almost no pain occurs during the insertion process.
A method of automatically distinguishing absorption or non-absorption of whole blood or blood plasma by using a reflective photosensor in an automatic immunoassay device including a round cartridge which may simultaneously perform the centrifugation and automatic analysis of a blood sample and a tip which may be moved up, down, left and right based on the round cartridge, the method includes: installing the reflective photosensor below the round cartridge; mounting the tip above the round cartridge, and continuously measuring blood non-absorption data in a range including a position where the blood is absorbed by using the reflective photosensor, collecting the measured data and storing the collected data while the tip is raised; continuously measuring blood absorption data by using the reflective photosensor while the tip is lowered and absorbs the blood present in the range including the position where the blood is absorbed from the round cartridge; and determining whether a type of the blood is whole blood or blood plasma, or whether the whole blood or the blood plasma is not absorbed by comparing the blood non-absorption data with the blood absorption data.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
The present invention relates to an amphiphilic polymer copolymer composed of a prepolymer polymerized by reacting polyol (P) and diisocyanate (R) and a chain-extender comprising one or more hydrophilic or hydrophobic functional groups (E1 or E2) and a method for preparing the same. Such a polymer is a biocompatible polymer as a thermoplastic polyurethane polymer, and it can be used as various medical polymers, and it has an advantage that a process can be simplified as it is easier to prepare and configure than the conventional blended medical polyurethane.
The present disclosure relates to a method for stabilizing a continuous glucose monitoring system. The method for stabilizing a continuous glucose monitoring system according to an embodiment of the present invention may comprise: a step of measuring biometric information by a sensor transmitter disposed in a part of a user's body so as to measure the user's biometric information; a step of transmitting, by the sensor transmitter, data on the measured biometric information (biometric information data) to a communication terminal; a stabilization step of stabilizing, by the communication terminal, the biometric information data received from the sensor transmitter; and a step of displaying, by the communication terminal, the biometric information data after the stabilizing step is completed, so as to allow the user to identify the biometric information data received from the sensor transmitter, wherein in the stabilization step, the communication terminal variably controls the time during which the biometric information data received from the sensor transmitter is stabilized. The present disclosure has an advantage in that the time during which data measured by a sensor transmitter is stabilized can be variably controlled according to sensor transmitters, and thus accurate biometric information data can be provided to a user.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
35.
METHOD FOR NEAR FIELD COMMUNICATION CONNECTION OF CONTINUOUS BLOOD GLUCOSE MONITORING SYSTEM
The present disclosure relates to a near field communication connection method of a continuous glucose monitoring system. A near field communication connection method of a continuous glucose monitoring system according to an embodiment of the present disclosure may include the steps of: acquiring connection information about a body attachment unit, which is attached to a human body and continuously monitors blood glucose, in order to connect communication between the body attachment unit and a communication terminal; using an identifier of the body attachment unit in the connection information to search for and select a body attachment unit matching the identifier of the body attachment unit from a device that can be communicatively connected to the communication terminal; and using an identification number of the body attachment unit in the connection information to connect communication between the selected body attachment unit and the communication terminal. According to the present invention, the body attachment unit of a continuous glucose monitor and a communication terminal are communicatively connected using the Bluetooth communication specification. Here, an image recognition code can be used to input the identification number of the body attachment unit to the communication terminal in order to establish the communicative connection, and thus the present invention has the effect of allowing the communicative connection between the body attachment unit and the communication terminal to be established more intuitively.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
36.
METHOD FOR TRANSMITTING AND RECEIVING BIOMETRIC INFORMATION WITHOUT LOSS IN CONTINUOUS BLOOD GLUCOSE MONITORING SYSTEM
The present disclosure relates to a method for transmitting or receiving biometric information in a continuous glucose monitoring system and, more specifically, to a method for transmitting or receiving biometric information, in which: when a sensor transmitter generates a transmission packet, the transmission packet is generated to include a generation identifier for identifying the transmission packet or biometric information according to a generation order of the transmission packet or the biometric information, and therefore the biometric information may be transmitted or received without a loss thereof via the generation identifier; and a transmission packet or biometric information, which a communication terminal has failed to receive, is correctly determined on the basis of a packet generation identifier or a total number of transmission packets, so that only biometric information or a transmission packet, which has failed to be received between the sensor transmitter and the communication terminal, may be transmitted or received in a distinguished manner.
The present disclosure relates to a continuous blood sugar measuring sensor member, wherein: since an electrode layer formed on one surface of a substrate is connected to a sensor contact point part on the other surface of the substrate through a via hole and thus two electrode layers may be formed on different opposite surfaces without having to be formed on the same surface of the substrate, the width of the substrate may be further reduced and an overall minimized and simplified structure may be ensured; since an electrode connection layer formed at the via hole is not formed in a shape of filling the via hole but is formed only on the inner circumferential surface, a filling defect occurring in a process of filling the via hole and a fault in electrical connection according thereto may be prevented and thus a more stable structure may be ensured; and since a plurality of via holes are formed, despite damage to or the occurrence of a defect in an electrode connection layer formed at one of the via holes, electrical connection is maintained by electrode connection layers formed at the remaining via holes, and thus more stable performance may be maintained.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
38.
COMMUNICATION CONNECTION METHOD FOR CONTINUOUS BLOOD GLUCOSE MONITORING SYSTEM
The present disclosure relates to a communication connection method for a continuous glucose monitoring system. A communication connection method for a continuous glucose monitoring system according to an embodiment of the present disclosure may comprise: a step in which, in order to connect communication between a communication terminal and a sensor transmitter attached to a human body so as to continuously monitor biometric information of the human body, the communication terminal receives information of the sensor transmitter from the sensor transmitter; a step of determining, on the basis of the received information, whether the sensor transmitter is a new sensor transmitter or an already used sensor transmitter; and a step in which, when the sensor transmitter is an already used transmitter, communication connection is controlled on the basis of use information of the already used sensor transmitter. The present disclosure is advantageous in that, if communication between a sensor transmitter inserted into a human body and a communication terminal for receiving glucose data from the sensor transmitter is disconnected, the communication between the existing sensor transmitter and the communication terminal can be quickly connected when the communication is reconnected.
The present disclosure relates to a sterilization packaging method for a body-attachable biometric monitoring device. Provided is a sterilization packaging method for a body-attachable biometric monitoring device, the method in which a sterilization packaging process can be performed in a convenient and simple manner, further contamination which can occur during a sterilization process is prevented, damages due to moisture and the like after the packaging is complete are also prevented and thus complete sterilization packaging can be performed, in order to separately perform a sterilization packaging step in two steps, primary packaging is performed for a sterilizable state and then sterilization is performed, secondary packaging is performed to maintain airtightness for a primary packaged article which has been sterilized and thus penetration by an external contaminant and the like during the sterilization and packaging processes is prevented to prevent damages to a biometric monitoring device, a separate adsorbent is positioned outside the primary packaged article and then the secondary packaging is performed and thus functional degradation of the adsorbent during the sterilization process is prevented to enable inner packaging of the adsorbent in an excellent functional state, and a moisture removal function can be performed stably to enable a complete sterilization packaging.
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
B65B 55/04 - Sterilising wrappers or receptacles prior to, or during, packaging
B65B 61/20 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for adding cards, coupons or other inserts to package contents
B65B 7/16 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
B65D 65/42 - Applications of coated or impregnated materials
40.
METHOD FOR MANUFACTURING INSERTION GUIDE NEEDLE FOR CONTINUOUS BLOOD GLUCOSE MONITORING DEVICE
The present disclosure relates to a method for manufacturing an insertion guide needle for a continuous blood glucose monitoring device. The present disclosure provides a method for manufacturing an insertion guide needle for a continuous blood glucose monitoring device, by which: an insertion guide needle can be manufactured through a cutting process and a bending process of a needle raw plate, so that a complicated manufacturing process is unnecessary, and can thus be easily manufactured through a simple process; an enlargement incision part for continuous enlargement and incision, etc. can be conveniently manufactured through such a simple processing process, so that a manufacturing cost thereof can be reduced and also the size accuracy of the insertion guide needle can be improved; and, particularly, in a process of inserting the insertion guide needle into skin, the insertion guide needle can be brought into point contact with the skin to cut the skin, and then can continuously cut the skin in an enlarged manner, so as to minimize pains which may occur in the process of inserting the insertion guide needle into the skin, thereby alleviating the sense of repulsion or tension at the time of using the continuous blood glucose monitoring device.
SOGANG UNIVERSITY PRESEARCH BUSINESS DEVELOPMENT FOUNDATION (Republic of Korea)
I-SENS, INC. (Republic of Korea)
Inventor
Shin, Woonsup
Quan, Yuzhong
Ha, Eunhyeon
Kim, Suk-Joon
Kang, Young Jea
Jeong, In Seok
Yang, Hyunhee
Kim, Minki
Abstract
The present invention provides an electrochemical biosensor comprising a carbon nanotube for measuring biosignals. The electrochemical biosensor for continuous glucose monitoring comprises an electrode to which a sensing film including an oxidoreductase, an electron transfer mediator, and a crosslinker is fixed, together with a carbon nanotube, wherein the oxidoreductase oxidizes a target substance and the electron thus generated in the oxidation process is transferred through the electron transfer mediator and the carbon nanotube, whereby the electrochemical biosensor can be used as a sensor having an excellent performance for continuous glucose monitoring.
The present disclosure relates to a body attachment device for continuous glucose monitoring and, more particularly, to a body attachment device for continuous glucose monitoring characterized in that as a user command for applying operating power of the body attachment device is inputted by an optical method or a touch method, operation of the body attachment device can be controlled by easily initiating application of battery power not only before the body attachment device is attached to the body but also after the body attachment device has been attached to the body. In addition, as the operation of the body attachment device is controlled by light or touch, it is possible to prevent erroneous operation of the body attachment device that occurs when a user touches, by mistake, a physical operation button formed in the body attachment device while using the body attachment device. Furthermore, the operating power can be stably provided.
The present disclosure relates to a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device is produced in a state in which a body attachment unit has been assembled inside an applicator, so as to minimize a user's additional work of attaching the body attachment unit to the body, thereby enabling the body attachment unit to be attached to the body only by simply activating the applicator. Particularly, the present invention provides a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device: includes a wireless communication chip in a body attachment unit so as to enable communication with an external terminal, thereby enabling simple and convenient use thereof, without additional work for connecting a separate transmitter, and easier maintenance; and is activated by a user's operation after the body attachment unit is attached to the body, so as to enable the operation start time to be adjusted to an appropriate time according to user's needs, and to enable the operation to start in a stabilized state so that blood glucose can be measured more accurately.
The present disclosure relates to a method for calibrating a blood glucose value in a continuous blood glucose measurement system. More particularly, blood glucose values can be accurately calibrated according to a calibration mode by differently selecting calibration modes for calibrating blood glucose values on the basis of whether the difference between a blood glucose value measured by a continuous blood glucose measurement system and a reference blood glucose value measured by a separate blood glucose meter is outside a set range. In addition, the blood glucose value of a user can be accurately calibrated by activating, to be scrolled on an input window, only the ranges of the blood glucose value and a reference blood glucose value calculated on the basis of a preset critical range, or by forcibly or automatically calibrating the blood glucose value by a second calibration mode which uses multiple reference blood glucose values, when a reference blood glucose value outside the reference blood glucose value range is input.
The present disclosure relates to a method of displaying biological information. More specifically, the method allows sequential biological information to be easily displayed and checked using a small area by having the biological information sequentially displayed while rotating over a passage of time corresponding to measurement times of the biological information, and furthermore, by having biological information measured at a most recent measurement time displayed at a reference line, or by allowing biological information at a desired measurement time to be moved to the reference line by a clockwise or counterclockwise rotation, or by having measurement times displayed in a radial fashion in a single circle for each unit period so as to enable a user to select a desired unit period in a left direction or a right direction, the method allows for a user to easily change and check the biological information at the desired measurement time or unit period.
The present disclosure relates to a composition for a crosslinking agent for the preparation of a sensing layer or a diffusion control layer of an electrochemical biosensor comprising genipin or a derivative thereof, in which due to the properties of genipin that can be extracted and used from plants, not only it has high biocompatibility compared to conventional crosslinking agents with high toxicity, but also it can easily confirm the progress of the reaction by measuring UV or measuring the amount of amine groups present when reacting with a compound having an amine group, for example, an electron transport medium, and additionally, it has the advantage of suppressing a rapid decrease in sensor life due to high concentration of glucose while maintaining an appropriate sensitivity to glucose.
C07D 311/94 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
47.
POLY(ALLYL GLYCIDYL ETHER)-BASED REDOX POLYMER AND ELECTROCHEMICAL BIOSENSOR USING SAME
The present disclosure relates to an oxidation-reduction polymer which can be used in an electrochemical sensor, and particularly, in a polymer backbone of an electron transfer medium of the electrochemical sensor. More specifically, the present disclosure relates to: an oxidation-reduction polymer which can be used in a poly (allyl glycidyl ether)-based electrochemical sensor including a repeating unit derived from allyl glycidyl ether; and an electron transfer medium and an electrochemical sensor including same, wherein the oxidation-reduction polymer is advantageous in confirming the completion of reaction during manufacture, has high immobilization efficiency of the transition metal complex, has low possibility of having problems of toxicity and side effects, and can add various functions.
C08G 65/334 - Polymers modified by chemical after-treatment with organic compounds containing sulfur
C08G 65/338 - Polymers modified by chemical after-treatment with inorganic and organic compounds
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
A cartridge capable of a centrifugation and an automatic analysis according to an embodiment of the present invention includes: at least two or more sample wells, a centrifugation well, a measuring well, and a tip receiving well, in which a container is formed into a lower portion along a circumference of a circular plate with a predetermined interval, wherein the centrifugation well is sealed with one lid paper along with at least two or more of the sample wells, a blood injection unit is further formed inside of a radius direction for the centrifugation well, the blood injection unit has an outer blood injection hole formed to be spaced inside the centrifugation well in the radius direction, an inclined passage that communicates with the centrifugation well from the outer blood injection hole, and a cover integrally attached to the outer blood injection hole to open and close the blood injection hole.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
49.
BODY ATTACHABLE UNIT FOR CONTINUOUS BLOOD GLUCOSE MEASUREMENT
The present disclosure relates to a body-attachable unit for continuously measuring blood glucose. As the body-attachable unit is manufactured to be assembled in an applicator, additional effort is minimized such that the body-attachable unit can be attached to the body by simply operating the applicator. In particular, since the body-attachable unit is provided with a wireless communication chip such that communication with an external terminal is possible, the body-attachable unit can be used simply and conveniently without additional work of connecting a separate transmitter, and thus can be maintained more easily. In addition, since the body-attachable unit is operated by an operation of a user after being attached to the body, the start time of the operation can be adjusted to an appropriate time according to the needs of the user. Accordingly, the body-attachable unit can be operated in a stabilized state, thereby allowing for more accurate blood glucose measurement.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
50.
POLYMER BLEND FOR CONTROLLING BLOOD GLUCOSE INFLUX, AND CONTINUOUS GLUCOSE MONITORING BIOSENSOR COMPRISING SAME
The present disclosure relates to a continuous glucose monitoring biosensor, and more specifically, to: a biosensor which controls the flow of blood glucose flowing into a body during implantation, thereby enabling continuous detection and quantification of the blood glucose with high sensitivity; and a continuous glucose monitoring device and method using same. When a polymer blend composition including a hydrophilic polymer and a hydrophobic polymer according to the present disclosure, a diffusion control membrane formed therefrom and a continuous glucose monitoring biosensor including the same are used, they have the advantage capable of controlling an excessive influx of blood glucose due to an increase in the rate of diffusion in the sensor, thus enabling manufacture of a sensor having excellent accuracy and durability.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
51.
OXIDATION-REDUCTION POLYMER INCLUDING TRANSITION METAL COMPLEX, AND ELECTROCHEMICAL BIOSENSOR USING SAME
The present disclosure relates to an oxidation-reduction polymer including a transition metal complex, which has a unique structure, and so can be prepared in a simpler step compared to a conventional method, and can increase the immobilization rate of the transition metal complex and facilitates the introduction of a functional group or a linker, a method for preparing the same and an electrochemical biosensor comprising the oxidation-reduction polymer.
C08F 226/06 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
C12Q 1/32 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present disclosure relates to a continuous glucose monitoring device. The present disclosure provides a continuous glucose monitoring device wherein: a body attachment unit is manufactured in the state in which the body attachment unit is assembled in an applicator, and thus a user's additional work for attaching the body attachment unit to the body is minimized and the body attachment unit can be attached to the body by simply operating the applicator; in particular, a wireless communication chip is disposed in the body attachment unit so as to communicate with an external terminal, and thus simple and convenient use can be achieved without any additional work for connection of a separate transmitter and maintenance and management can also be easily performed; and the monitoring operation is started by the user's manipulation after the body attachment unit is attached to the body, and thus the user can adjust the operation start time to an appropriate point as necessary and the operation can be started in a stabilized state so as to enable more accurate glucose monitoring.
The present invention relates to a continuous blood glucose measurement device which is produced with an assembled body attachment unit inside an applicator so as to minimize a user's additional work of attaching the body attachment unit to the body, thereby enabling the body attachment unit to be attached to the body by simply activating the applicator, and, particularly, the present invention provides a continuous blood glucose measurement device which: is provided with a wireless communication chip in a body attachment unit so as to enable communication with an external terminal, thereby enabling simple and convenient use, without additional work of connecting a separate transmitter, and easier maintenance; and is activated by the user after the body attachment unit is attached to the body so as to enable the operation start time to be adjusted to an appropriate time according to user's needs, and to enable the operation to start in a stabilized state so that blood glucose can be measured more accurately.
The present invention relates to a body attachment unit for continuous blood glucose monitoring, in which a body attachment unit is manufactured so as to be assembled in an applicator, thereby minimizing additional work and allowing attachment of the body attachment unit to a body simply by operation of the applicator. In particular, a wireless communication chip is provided in the body attachment unit to enable communication with an external terminal, thereby enabling simple and convenient use without additional work of connecting a separate transmitter, and allowing easier maintenance. In addition, activation occurs by a user's operation after the body attachment unit is attached to the body, such that an activation start time can be adjusted to a time appropriate to the user's needs, and activation occurs in a stabilized state, thereby allowing more accurate blood glucose monitoring.
The present invention relates to a body attachment unit for continuous blood glucose monitoring, in which a body attachment unit is manufactured so as to be assembled in an applicator, thereby minimizing additional work and allowing attachment of the body attachment unit to a body simply by operation of the applicator. In particular, a wireless communication chip is provided in the body attachment unit to enable communication with an external terminal, thereby enabling simple and convenient use without additional work of connecting a separate transmitter, and allowing easier maintenance. In addition, activation occurs by a user's operation after the body attachment unit is attached to the body, such that an activation start time can be adjusted to a time appropriate to the user's needs, and activation can occur in a stabilized state, and thereby allowing more accurate blood glucose monitoring.
The present invention relates to a continuous blood glucose measurement apparatus which, by manufacturing a body-attachable unit in an assembled state inside an applicator, minimizes the additional work by a user for attaching the body-attachable unit to the body and thus enables the body-attachable unit to be attached to the body simply by means of operating the applicator, and, by providing a wireless communication chip on the body-attachable unit and enabling communication with an external terminal, can be used in a simple and convenient manner without the additional work of connecting a separate transmitter and enables easier maintenance and management, and, by having the operation of the body-attachable unit initiated by means of the user's manipulation after being attached to the body, enables the operation initiation point to be adjusted to an appropriate point as necessary by the user, enables an operation initiation in a stabilized state and thus enables more accurate blood glucose measurement.
An apparatus for controlling operations of a continuous glucose monitoring system. When a continuous glucose monitoring system is located within a certain distance from a user terminal, power of a battery is supplied to the continuous glucose monitoring system through a power switch switched on by an enable signal generated by a near field communication module, thereby operating the continuous glucose monitoring system without user intervention. The near field communication module provides connection information to the user terminal, thereby automatically performing a pairing connection with the user terminal using the near field communication module and a bluetooth communication module. When the pairing connection with the user terminal is completed, an enable signal generated by the bluetooth communication module is provided to the power switch, thereby maintaining the pairing connection with the user terminal even when the user terminal is outside of range for near field communication.
The present disclosure relates to a continuous blood sugar measuring device, and provides a continuous blood sugar measuring device which is capable of minimizing additional work of a user in order to attach a body attachment unit, by manufacturing the body attachment unit to be assembled inside an applicator so that the body attachment unit can be attached to the body simply by operating the applicator and, particularly: communicating with an external terminal by providing a wireless communication chip in the body attachment unit so that simple and convenient use is possible and maintenance can easily be performed without the additional work of connecting a separate transmitter; initiating operation by a manipulation of the user, after attaching the body attachment unit to the body, so that an operation initiation time can be adjusted to a suitable time according to the need of the user; and initiating operation in a stabilized state to enable a more accurate measurement of blood sugar.
The present invention has been made in an effort to provide an analyte concentration measurement method using artificial intelligence deep learning, capable of extracting useful features that are not known in advance by humans through deep learning using artificial neural networks by imaging input signals obtained during the measurement time from samples with information (labels) to construct a data set and estimating a result value by applying an algorithm obtained through learning in this way, compared with conventional measurement techniques that are applied by devising formulas or methods that directly extract features for a long time by experts in related fields in order to extract effective features.
The present disclosure relates to a continuous glucose monitoring device, in which a body attachment unit is manufactured so as to be assembled in an applicator, thereby minimizing additional work for a user in attaching the body attachment unit to a body, and allowing attachment of the body attachment unit to the body simply by operation of the applicator. In particular, a wireless communication chip is provided in the body attachment unit to enable communication with an external terminal, thereby enabling simple and convenient use without additional work of connecting a separate transmitter, and allowing easier maintenance. In addition, the continuous glucose monitoring device is activated by a user's operation after the body attachment unit is attached to the body, such that an activation start time can be adjusted to a time appropriate to the user's needs, and the continuous glucose monitoring device can be activated in a stabilized state, and thereby can monitor blood glucose more accurately.
The present disclosure relates to a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device is produced in a state in which a body attachment unit has been assembled inside an applicator, so as to minimize a user's additional work of attaching the body attachment unit to the body, thereby enabling the body attachment unit to be attached to the body only by simply activating the applicator. Particularly, the present invention provides a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device: includes a wireless communication chip in a body attachment unit so as to enable communication with an external terminal, thereby enabling simple and convenient use thereof, without additional work for connecting a separate transmitter, and easier maintenance; and is activated by a user's operation after the body attachment unit is attached to the body, so as to enable the operation start time to be adjusted to an appropriate time according to user's needs, and to enable the operation to start in a stabilized state so that blood glucose can be measured more accurately.
The present disclosure relates to a body attachment unit for continuous blood glucose measurement, in which the body attachment unit is manufactured so as to be assembled in an applicator, thereby minimizing additional work and allowing attachment of the body attachment unit to a body simply by operation of the applicator. In particular, a wireless communication chip is provided in the body attachment unit to enable communication with an external terminal, thereby enabling simple and convenient use without performing additional work of connecting a separate transmitter, and allowing easier maintenance. In addition, activation occurs by a user's operation after the body attachment unit is attached to the body, such that an activation start point in time can be adjusted to an appropriate point in time according to the user's needs, and activation occurs in a stabilized state, thereby providing the body attachment unit allowing more accurate blood glucose measurement.
The present disclosure relates to a continuous blood glucose measurement body attachment unit, and provides a continuous blood glucose measurement body attachment unit, which is manufactured in an assembled state in an applicator so as to minimize separate additional operations, such that the body attachment unit can be attached to the body with only a simple operation of the applicator and, particularly, the body attachment unit has a wireless communication chip so as to be capable of communicating with an external terminal, thereby enabling simple and convenient usage without an additional operation in which a separate transmitter must be connected and enabling maintenance to be more easily performed, and after the body attachment unit is attached to the body, an operation starts by the control of a user, such that an operation start time point can be adjusted to an appropriate time point according to the needs of the user, and an operation can start in a stabilized state, such that blood glucose can be more accurately measured.
The present disclosure relates to a continuous blood glucose measurement body attachment unit, and provides a continuous blood glucose measurement body attachment unit, which is manufactured in an assembled state in an applicator so as to minimize separate additional operations, such that the body attachment unit can be attached to the body with only a simple operation of the applicator and, particularly, the body attachment unit has a wireless communication chip so as to be capable of communicating with an external terminal, thereby enabling simple and convenient usage without an additional operation in which a separate transmitter must be connected and enabling maintenance to be more easily performed, and after the body attachment unit is attached to the body, an operation starts by the control of a user, such that an operation start time point can be adjusted to an appropriate time point according to the needs of the user, and an operation can start in a stabilized state, such that blood glucose can be more accurately measured.
The present invention relates to a body attachment unit for continuous glucose monitoring. The present invention provides a body attachment unit for continuous glucose monitoring, wherein: the body attachment unit is manufactured in the state in which the body attachment unit is assembled in an applicator, and thus separate additional work is minimized and the body attachment unit can be attached to the body by simply operating the applicator; in particular, a wireless communication chip is disposed in the body attachment unit so as to communicate with an external terminal, and thus simple and convenient use can be achieved without any additional work for connection of a separate transmitter and maintenance and management can also be easily performed; and the monitoring operation is started by a user's manipulation after the body attachment unit is attached to the body, and thus the user can adjust the operation start time to an appropriate point as necessary and the operation can be started in a stabilized state so as to enable more accurate glucose monitoring.
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present invention relates to a method for managing biometric information and, more specifically, to a method for managing biometric information capable of preventing a use of a sensor module of which an expiration date has expired or a defective sensor module, by determining the validity of a sensor module of a continuous biometric information measuring device on the basis of the generation date of sensor usage information or production lot information received from the continuous biometric information measuring device, and preventing re-use or shared use of the sensor module on the basis of user information provided in a measurement message received from the continuous biometric information measuring device.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
71.
Sensor applicator assembly for continuous glucose monitoring system
The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
An artificial neural network deep learning-based analyte analysis system utilizing a system is provided. The system includes a biometric information measurer, and a biometric information analysis artificial intelligence-based deep learning server that includes: a signal acquiring portion acquiring a signal through an electrochemical reaction, which occurs due to injection of blood collected by the biometric information measurer into a strip that includes a pair of electrodes; a signal processor pre-processing the signal acquired by the signal acquiring portion as a signal for artificial intelligence deep learning; a biometric information measurement algorithm generator that automatically extracts features by using an artificial neural network deep learning-based method for a biometric information measurement algorithm optimized using the signal having been processed through the signal processor; and an optimized algorithm result providing portion that provides the optimized biometric information measurement algorithm to the biometric information measurement apparatus.
The purpose of the present invention is to provide a fungus-derived FADGDH that has a direct electron transfer ability. Provided is a fusion protein comprising a fungus-derived FADGDH or a mutant thereof and a cytochrome molecule connected to the N-terminus of the FADGDH or variant thereof.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used aspsposables, thereby allowing accurate and safe use and convenient maintenance.
An apparatus for measuring a concentration of an analyte in a bio-sample using an electrochemical bio-sensor, includes a connector with a sample cell in which an oxidation/reduction enzyme and an electron transfer mediator are fixed and a working electrode and an counter electrode are provided; a digital-to-analog converter circuit configured to apply a constant DC voltage to start the oxidation/reduction reaction of the analyte, proceed with an electron transfer reaction, and apply a Λ-step ladder-type perturbation potential for fluctuating a potential of the sample cell after applying the constant DC voltage; and a microcontroller configured to control the digital-to-analog converter circuit and directly obtain a concentration value of the analyte from a calibration equation using the Λ-step ladder-type perturbation potential. The apparatus can improve measurement accuracy by effectively minimizing a matrix interference effect of a background material in a bio-sample, particularly an inaccuracy caused by a change in hematocrit.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 33/487 - Physical analysis of biological material of liquid biological material
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
A61B 5/1495 - Calibrating or testing in vivo probes
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01N 27/48 - Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage
G01N 27/42 - Measuring deposition or liberation of materials from an electrolyte; Coulometry, i.e. measuring coulomb-equivalent of material in an electrolyte
76.
Sensor applicator assembly for continuous glucose monitoring system
The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
The present invention relates to a kit for quantitative analysis of glycated hemoglobin (HbA1c), and the kit for quantitative analysis of HbA1c according to the present invention has excellent long-term stability of an enzyme reagent and thus has an effect of easily overcoming the disadvantages of the conventional reagents used in enzyme assays (e.g., storage, accuracy, portability, convenience of use, etc.).
The present invention relates to a strip ejection apparatus for a blood glucose meter, wherein: an ejector block moving to eject a measurement strip is received in the space inside a housing, whereby it is possible to make the apparatus compact, thereby enhancing space efficiency of the blood glucose meter; components can be mounted on a PCB of the blood glucose meter in units of modules as they are, without any additional separate assembly for the components, whereby it is possible to enhance efficiency of a manufacturing process; a guide protrusion coupled with an ejection switch of the blood glucose meter is selectively formed on the upper or lower portion of the ejector block or formed on both the upper and lower portions thereof, whereby it is possible to enhance the degree of freedom in design of the mounting position of the ejection switch; and the strip ejection apparatus can be applied to various types of blood glucose meters so that it is possible to standardize the type of strip ejection apparatus, thereby reducing manufacturing cost, as well as facilitating component management.
The present disclosure relates to an electron transfer mediator comprising the osmium complex or a salt thereof, a reagent composition for an electrochemical biosensor, and an electrochemical biosensor, where the osmium compound or its salt maintains a stable oxidation-reduction form for an extended time period, a capacity to react with oxidoreductase being capable of performing the redox reaction of the target analytes, and no effect of oxygen partial pressure.
C12M 1/40 - Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
80.
Circular type cartridge enabling centrifugation and modular automatic analyzer using the same
A modular automatic analyzer using a circular type cartridge enabling centrifugation according to an exemplary embodiment of the present invention includes: a main body frame; an X-axis conveying unit which reciprocally moves in an X-axis direction with respect to the main body frame; a circular type cartridge accommodating housing which is installed with respect to the X-axis conveying unit so as to be reciprocally movable in the X-axis direction by the X-axis conveying unit, a single rotation drive unit which is installed in the circular type cartridge accommodating housing and is rotated step by step at a predetermined interval or rotated at a high speed for centrifugation, a circular type cartridge which is installed at an upper surface of the circular type cartridge accommodating housing so as to be rotatably connected to the rotation drive unit and has wells disposed to be spaced apart from each other at predetermined intervals in a circumferential direction of a disc-shaped main body, a tip lifting unit which picks up and moves a tip upward and downward, a measurement unit which measures a reaction in the well, a Z-axis drive unit which is provided with the tip lifting unit and the measurement unit and reciprocally operates in a Z-axis direction with respect to the main body frame, and a control unit C which controls an automatic immunity analyzer.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 35/04 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations - Details of the conveyor system
B04B 15/02 - Other accessories for centrifuges for cooling, heating, or heat insulating
B04B 5/04 - Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
A portable blood glucose measurement device is provided. The device includes, in an externally exposed way, a temperature measurement medium of which the temperature quickly changes according to outside temperature changes provided on one side surface of a case. The device further includes an infrared temperature sensor. The device measures the temperature of the temperature measurement medium with the infrared temperature sensor in a noncontact manner, and calculates a blood glucose measurement result by considering the measured temperature so as to accurately reflect the outside temperature of an actual blood glucose measuring environment. The temperature measurement medium can be configured to sensitively respond to the outside temperature independently from the case such that the temperature of the temperature measurement medium, in accordance with the change in outside temperature, quickly and accurately changes so as to measure the temperature in a more accurate manner.
A method for measuring a concentration of an analyte in a bio-sample using an electrochemical bio-sensor according to an exemplary embodiment of the present invention is characterized by a step of obtaining predetermined features from induced currents obtained by applying a DC voltage according to chronoamperometry in which, after a whole blood sample is injected to the electrochemical bio-sensor, a concentration of an analyte is obtained from an induced current obtained by applying a DC voltage for a certain time and from all induced currents obtained by further applying several step-ladder perturbation potentials for a short time subsequent to the DC voltage for the certain time, and is also characterized by minimization of a measurement error caused by a hindering material by forming a calibration equation by combining the at least one feature in a function and optimizing various conditions of the bio-sample through DeletedTextsmultivariable analysis. With this configuration, a perturbation potential application method added to a conventional measurement method can maintain a bio-sensor and a measuring apparatus already used, a line used in the measuring apparatus, and calibration of amperometry as they are, improve accuracy in measurement by effectively minimizing a matrix interference effect of a background material in a bio-sample, particularly an inaccuracy caused by a change in hematocrit, and also remarkably improve accuracy in measurement by simply upgrading a measurement program of a conventional measuring apparatus.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 33/487 - Physical analysis of biological material of liquid biological material
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
A61B 5/1495 - Calibrating or testing in vivo probes
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01N 27/48 - Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage
G01N 27/42 - Measuring deposition or liberation of materials from an electrolyte; Coulometry, i.e. measuring coulomb-equivalent of material in an electrolyte
83.
Method for producing nanofibers capable of storing and transferring nitric oxide and nanofibers capable of storing and transferring nitric oxide produced thereby
The present invention relates to a method for producing nanofibers storing and transferring nitric oxide, and nanofibers produced thereby. The present invention may include: a filling step for filling a first material with nitric oxide; a synthesis step for synthesizing a second material having a functional group capable of covalently bonding to the first material; a sol-gel reaction step for carrying out a sol-gel reaction of the first material filled with nitric oxide with the second material to produce a gel; and an electrospinning step for electrospinning the gel to produce a nanofiber.
D01F 6/36 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from copolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds comprising unsaturated carboxylic acids or unsaturated organic esters as the major constituent
D01D 5/00 - Formation of filaments, threads, or the like
D04H 1/728 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
D01F 6/88 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
D01F 9/08 - Man-made filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments of inorganic material
84.
Biochemical analysis cartridge having improved operability
The present invention relates to a biochemical analysis cartridge having improved operability. More particularly, the present invention provides a biochemical analysis cartridge including an insertion-type sample cartridge and a reaction cartridge receiving the insertion-type sample cartridge, in which, as the sample cartridge is inserted into the reaction cartridge, a reaction solution chamber moves toward a broken part of a covertape so as to automatically supply the reaction solution stored in the chamber. The biochemical analysis cartridge having improved operability according to the present invention can induce the mixing between a sample and a reaction solution by simply inserting them into the reaction cartridge and a reaction thereafter, thereby minimizing the process of a measurer to intervene in the assay, and subsequently improving user convenience and operability.
The present invention relates to a stabilizing composition useful for improving the stability of reagent for redox reaction, and a reagent composition for redox reaction having an improved stability. The reagent composition for redox reaction can be applied for a reagent for electrochemical biosensor.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
The present invention relates to an electrochemical biosensor with improved hematocrit measurement accuracy for measuring blood glucose. According to the present invention, an electrochemical biosensor including a first electrode part for correcting a measured hematocrit value and a second electrode part for measuring a glucose concentration is effective in improving accuracy of a measured hematocrit value and in more improving accuracy of a measured blood glucose concentration using the measured hematocrit values for correction, because an insulation cover is made thinner than a working electrode and an auxiliary electrode, so that areas of a first working electrode and a first auxiliary electrode of the first electrode part exposed to a blood sample become equal; a distance between the first working electrode and the second working electrode becomes constant; and electrode areas are maintained constantly by the insulation cover even when a positioning error occurs during printing.
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
87.
Sensor cartridge for detecting component of at least one sample
The present invention relates to a cartridge for sensor for detecting the concentrations of one or more components in a sample. The cartridge for sensor for detecting one or more components in a sample of the present invention not only enables quantitative measurement of one or more components in a sample by one time sample injection but also facilitates mass-production with low cost owing to the simple structure and easiness in preparation and carry. Therefore, the cartridge of the present invention can be effectively used as the biosensor cartridge for field measurement.
Disclosed is a hemolysis reagent composition for the quantitative analysis of glycated hemoglobin (HbAlc) via an enzymatic method. The hemolysis reagent compositions of the present invention containing a zwitterionic surfactant and a nitrous compound considerably accelerate hemolysis rate due to the presence of the zwitterionic surfactant, and also induce the N-terminal β-chain of hemoglobin released by hemolysis to be exposed to the outside of the hemoglobin molecule and assists the participation of a greater number of molecules in the reaction, thereby improving reaction sensitivity and reaction rate of the glycated hemoglobin, and the nitrous compound makes the protein structure of the hemoglobin flexibly modified so that the amino acid sequence of the N-terminal β-chain of hemoglobin can be readily cut off, thereby significantly reducing the entire time required for the measurement and improving the accuracy of the measurement.
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
C07C 309/14 - Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
G01N 33/72 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. hemoglobin, bilirubin
89.
Personal blood glucose meter and abnormal measurement detection method using same
A personal blood glucose meter and a method for sensing abnormal measurement using the same are disclosed. A personal blood glucose meter includes: a sensor strip for collecting and applying a blood sample, wherein the sensor strip includes a reagent; an electrode unit including a plurality of electrodes for receiving the blood sample from the sensor strip to generate electric current based on potential differences; an MCU for measuring currents value generated from the electrode unit to determine whether a glucose value of the blood sample is normal or abnormal; a potential supply unit for applying a predetermined potential to the electrode unit; and a display unit displaying resultant output from the MCU.
Provided are an amperometric sensor and device for electrochemically quantifying nitrosothiol (RSNO), which is associated with storage and delivery of nitric oxide (NO) in the human body. The amperometric sensor for measuring a concentration of RSNO includes an electrode configured to measure an electric current generated by an oxidation reaction of NO, and a means configured to start and stop photo-induced decomposition of RSNO. Here, the electric current is measured by the oxidation reaction of NO before and after the photo-induced decomposition of RSNO. The amperometric sensor may measure separate signals of RSNO and NO, which are present in the sample at the same time, using one electrode, thereby preventing an inhibition action caused by NO during the measurement of RSNO. Also, the amperometric sensor is simple in structure and easy to manufacture and may be applied to manufacture of a small electrode, and thus may be developed as a sensor for in vivo measurements.
A composition of redox-reagent containing metal-containing complex and thionine or its derivative as electron transfer mediator for use in an electrochemical biosensor, and a biosensor containing the same are provided. With the increase in reaction rate between redox enzyme-thionine (or its derivative)-metal-containing complex in the composition of redox-reagent containing metal-containing complex and thionine or its derivative, glucose detection efficiency markedly increases, and the composition is hardly influenced from high humidity and interfering substances. Accordingly, the composition of redox-reagent is useful in fabricating an electrochemical biosensor for detecting glucose in blood.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
I-SENS INC. (Democratic People's Republic of Korea)
Inventor
Planman, Jukka
Planman, Tuomas
Abstract
The present invention relates to a health monitoring device for measuring blood or tissue indicators and a strip cassette. The device comprises a body having first and second openings, a piercing means being connected to the body and having a piercing head, the piercing means being arranged to extend from the first opening and cockable and releasable for piercing the skin with the piercing head, and a space into which a number of sensor strips can be arranged so that the strips can be brought out from the body one at a time. The device further comprises a shutter that is functionally connected to the body and has a first position arranged to tightly close the first and second openings, and a second position for allowing one sensor strip to be pushed from the first opening into sampling position and for exposing the first and second openings.
A cartridge for an apparatus for analyzing blood chemistry includes an apparatus frame having a compartment; a cartridge that is inserted into the compartment of the apparatus frame and includes a sensor card, a solution valve unit, and a blood introducing unit; a controller that receives a signal generated from the sensor card and processes the signal; a lever for the blood introducing unit connected to the apparatus frame; a power transmitting unit that is provided to the apparatus frame and transmits power of the lever for the blood introducing unit to open/close the blood introducing unit of the cartridge; a solution transporting unit that is provided to the apparatus frame and transports the solutions; and a driving unit that actuates the solution valve unit of the cartridge by the controller and opens or closes the tubing flowing of the solutions.
A biosensor can be measured by a method that includes: determining malfunction of a production lot information sensing unit; alerting malfunction when the production lot information sensing unit malfunctions; encoding the production lot information through the production lot information sensing unit when the production lot information sensing unit does not malfunction; and detecting a component of a sample through a biosensor strip by using the encoded production lot information.
Disclosed is an electrochemical biosensor having a sample introduction channel in which an insulator is employed to introduce a small amount of a sample uniformly and accurately and to adjust an area of a working electrode, thereby guaranteeing the accurate quantitative analysis of a sample. Provided with a sample collection barrier at a sample entrance, the biosensor allows a sample to be introduced at higher accuracy and to be analyzed with higher reproducibility and reliability.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
The present invention provides a solution bag that is used for medical treatment and stores solution used for an apparatus for analyzing blood chemistry that measures and analyzes the concentrations of electrolytes, the partial pressures of gases, and the concentrations of metabolites or the volume ratio of red blood cells contained in blood. The solution bag for an apparatus for analyzing blood chemistry of the present invention includes: a receptacle that contains a solution; a valve body that is attached to the receptacle and has a through-hole longitudinally formed therein; a valve spool that is disposed in the through-hole of the valve body; and a solution leakage preventing unit that is disposed in the valve spool, in which the valve body has a flow channel and a solution discharging pipe spaced at a predetermined distance from each other.
Disclosed is an electrochemical biosensor measuring device which can be used together with an electrochemical biosensor. The biosensor measuring device comprises an electrical connection portion which is electrically connected with the electrodes of the biosensor upon the insertion of the biosensor there into, and a connector having a structure in which at least one light absorption or reflection path sequentially comprising a light emitter-production lot information identification portion-detector unit is provided to identify the production lot information recorded in the biosensor. The electrochemical biosensor measuring device can automatically identify the production lot information of the biosensor, encoded in the form of a hue or hole marks, upon the insertion of the electrochemical biosensor into the measuring device, thereby obviating the need to manually input the production lot information of the biosensor. Thus, inconvenience and the frequency of errors, which occur when a user personally inputs the production lot information, can be reduced, with the result that the measured values can be conveniently and accurately acquired.
An electrochemical biosensor and a biosensor measuring device. The electrochemical biosensor includes a plurality of electrodes, capillary sample cell portions, reaction reagent layers, electrode connection portions, and a production lot information identification portion. The production lot information identification portion is configured such that the production lot information is recorded thereon has one or more infrared absorption/reflection marks, which indicate information about differences between production lots through the printing and/or attachment of colored or colorless materials, having differences in absorbency or reflectivity of infrared rays, in conformity of a predetermined pattern or through the attachment of transparent films. The electrochemical biosensor measuring device includes a plurality of integrated photo-reflector sensing devices that emit and receive infrared rays to identify the production lot information recorded on the production lot information identification portion of the biosensor.
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
G06K 9/36 - Image preprocessing, i.e. processing the image information without deciding about the identity of the image
G03B 7/08 - Control effected solely on the basis of the response, to the intensity of the light received by the camera, of a built-in light-sensitive device
patents
